Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Youli Jian"'
Autor:
Caitlin Morris, Olivia K Foster, Simran Handa, Kimberly Peloza, Laura Voss, Hannah Somhegyi, Youli Jian, My Van Vo, Marie Harp, Fiona M Rambo, Chonglin Yang, Greg J Hermann
Publikováno v:
PLoS Genetics, Vol 14, Iss 11, p e1007772 (2018)
Cell type-specific modifications of conventional endosomal trafficking pathways lead to the formation of lysosome-related organelles (LROs). C. elegans gut granules are intestinally restricted LROs that coexist with conventional degradative lysosomes
Externí odkaz:
https://doaj.org/article/5e310e972da646db91a3cc30366a59b0
Autor:
Didi Chen, Youli Jian, Xuezhao Liu, Yuanya Zhang, Jingjing Liang, Xiaying Qi, Hongwei Du, Wei Zou, Lianwan Chen, Yongping Chai, Guangshuo Ou, Long Miao, Yingchun Wang, Chonglin Yang
Publikováno v:
PLoS Genetics, Vol 9, Iss 5, p e1003517 (2013)
Clathrin and the multi-subunit adaptor protein complex AP2 are central players in clathrin-mediated endocytosis by which the cell selectively internalizes surface materials. Here, we report the essential role of clathrin and AP2 in phagocytosis of ap
Externí odkaz:
https://doaj.org/article/769d8d56efc2488e8f99b0c0c9e1bdde
Autor:
Yixuan Wang, Baotao Ma, Youli Jian, Shi-Ting Wu, Wong, Alex, Wong, Justin, Bonder, Edward M., Xiangjian Zheng
Publikováno v:
FEBS Journal; Mar2024, Vol. 291 Issue 5, p1008-1026, 19p
Publikováno v:
Journal of Cell Biology. 222
Lysosomal integrity is vital for cell homeostasis, but the underlying mechanisms are poorly understood. Here, we identify CLH-6, the C. elegans ortholog of the lysosomal Cl−/H+ antiporter ClC-7, as an important factor for protecting lysosomal integ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ead5c115b09d7116690cda2955fd8bd
https://doi.org/10.1083/jcb.202210063
https://doi.org/10.1083/jcb.202210063
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Loss to follow-up (LTFU) in tuberculosis (TB) management increases morbidity and mortality, challenging effective control strategies. This study aims to develop and evaluate machine learning models to predict loss to follow-up in TB patients
Externí odkaz:
https://doaj.org/article/3a75d19059b5428393d341e14b3069bc
Publikováno v:
Journal of Cell Biology. 221
Multivesicular bodies (MVBs) contain intralumenal vesicles that are delivered to lysosomes for degradation or released extracellularly for intercellular signaling. Here, we identified Caenorhabditis elegans filamin FLN-2 as a novel regulator of MVB b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d929666b6968fc747c5e90d36a2a079
https://doi.org/10.1083/jcb.202201020
https://doi.org/10.1083/jcb.202201020
Publikováno v:
J Neurosci
Mutations in theAminoadipate-Semialdehyde Synthase(AASS) gene encoding α-aminoadipic semialdehyde synthase lead to hyperlysinemia-I, a benign metabolic variant without clinical significance, and hyperlysinemia-II with developmental delay and intelle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0945622786a16ebee2a7859fa4bd9136
https://pubmed.ncbi.nlm.nih.gov/35135854
https://pubmed.ncbi.nlm.nih.gov/35135854
Autor:
Jinglin Li, Qiuyuan Yin, Yubing Liu, Nan Xuan, Qiwen Gan, Yudong Jing, Chonglin Yang, Qian Zhang, Xiaochen Wang, Xin Wang, Kai Liu, Youli Jian, Junxiang Zhou
Publikováno v:
The Journal of Cell Biology
How lysosomes reform following phagolysosomal digestion of apoptotic cells is poorly understood. Gan et al. reveal that the amino acid transporter SLC-36.1 cooperates with PtdIns3P 5-kinase to control phagocygtic lysosome reformation in Caenorhabditi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ba6c04427306e5a35e778802190bb9a
https://doi.org/10.1083/jcb.201901074
https://doi.org/10.1083/jcb.201901074
Publikováno v:
J Neurosci
Multiciliated ependymal cells line the ventricle wall and generate CSF flow through ciliary beating. Defects in ependymal cells cause hydrocephalus; however, there are still significant gaps in our understanding the molecular, cellular and developmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7470b7fc83ba4520fd0c3064ddb29158
https://pubmed.ncbi.nlm.nih.gov/34815315
https://pubmed.ncbi.nlm.nih.gov/34815315
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
IntroductionThe increasing incidence of stroke globally has led to dysphagia becoming one of the most common complications in stroke patients, with significant impacts on patient outcomes. Accurate early screening for dysphagia is crucial to avoid co
Externí odkaz:
https://doaj.org/article/918161fa744f4d35a446f027e06260dd