Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Youko Osawa"'
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Akademický článek
A palindromic CpG-containing phosphodiester oligodeoxynucleotide as a mucosal adjuvant stimulates plasmacytoid dendritic cell-mediated T(H)1 immunity.
Autor: Jun-ichi Maeyama, Hisakazu Takatsuka, Fumiko Suzuki, Ayumi Kubota, Satomi Horiguchi, Takako Komiya, Ichiroh Shimada, Eri Murata, Youko Osawa, Harukazu Kitagawa, Takasumi Matsuki, Masanori Isaka, Saburo Yamamoto, Sumiko Iho
Publikováno v: PLoS ONE, Vol 9, Iss 2, p e88846 (2014)
BACKGROUND: CpG oligodeoxynucleotides (ODNs), resembling bacterial DNA, are currently tested in clinical trials as vaccine adjuvants. They have the nuclease-resistant phosphorothioate bond; the immune responses elicited differ according to the CpG OD
Externí odkaz: https://doaj.org/article/c30f14877ee548c68c65610bec0eed1a
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3
Cytosine–phosphate–guanosine-DNA induces CD274 expression in human B cells and suppresses T helper type 2 cytokine production in pollen antigen-stimulated CD4-positive cells
Autor: Youko Osawa, Norihiko Narita, Yumi Ito, Takechiyo Yamada, Seita Kubo, Shigeharu Fujieda
Publikováno v: Clinical and Experimental Immunology. 169:1-9
Summary Co-stimulatory molecules are important for regulating T cell activation and immune response. CD274 [programmed death ligand 1 (PD-L1), B7-H1] has emerged as an important immune modulator that can block T cell receptor signalling. We have inve
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::836d8b14386dc2fe52ce155fd5c7ff19
https://doi.org/10.1111/j.1365-2249.2012.04585.x
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4
Cough reflex induced by capsaicin inhalation in patients with dysphagia
Autor: Akihiro Kojima, Youko Osawa, Hiroshi Sunaga, Yoshimasa Imoto, Shigeharu Fujieda
Publikováno v: Acta Oto-Laryngologica. 131:96-100
We conclude that the capsaicin inhalation test is useful to directly assess cough reflex and sensation around the larynx, while it indirectly reflects central nervous system function.To understand the state of the cough reflex before patients with dy
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7da5335ef54659527c45e0531bd13aa6
https://doi.org/10.3109/00016489.2010.516013
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5
Two Cases of Invasive Aspergillus Sinusitis Showing Orbital Apex Syndrome
Autor: Norihiko Narita, Shigeharu Fujieda, Yoshimasa Imoto, Youko Osawa, Toshihisa Ito, Akihiro Kojima, Hiroshi Sunaga
Publikováno v: Practica Oto-Rhino-Laryngologica. 103:439-446
Fungal sinusitis is fairly common and often incidentally diagnosed in X-ray or computed tomography imaging (CT). Most cases are largely asymptomatic and noninvasive. In invasive cases, subjects are frequently immunocompromised hosts suffering from di
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e0bd3f0b97ca9849c0eba9232ad7a20b
https://doi.org/10.5631/jibirin.103.439
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6
Association of serum interleukin-33 level and the interleukin-33 genetic variant with Japanese cedar pollinosis
Autor: Koubun Yasuda, Youko Osawa, M. Harada, Mayumi Tamari, Shigeharu Fujieda, Tomomitsu Hirota, Yusuke Nakamura, Tomohiro Yoshimoto, Kenji Nakanishi, Kimihiro Okubo, Masafumi Sakashita
Publikováno v: Clinical & Experimental Allergy. 38:1875-1881
Summary Background IL-33, an IL-1-like cytokine, is a ligand for IL1RL1, which is an important effector molecule of type 2 T helper responses. Although IL-33/IL1RL1 interaction has been suggested to be important in induction of allergic airway inflam
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd75a70b87b681756da47d6dfa658f4e
https://doi.org/10.1111/j.1365-2222.2008.03114.x
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7
Collaborative Action of NF-κB and p38 MAPK Is Involved in CpG DNA-Induced IFN-α and Chemokine Production in Human Plasmacytoid Dendritic Cells
Autor: Youko Osawa, Hisakazu Takatsuka, Saburo Yamamoto, Shigeharu Fujieda, Sumiko Iho, Takayuki Takahashi, Satomi Horiguchi, Yoshimasa Urasaki, Takasumi Matsuki, Rumiko Takauji
Publikováno v: The Journal of Immunology. 177:4841-4852
CpG DNA induces plasmacytoid dendritic cells (pDC) to produce type I IFN and chemokines. However, it has not been fully elucidated how the TLR9 signaling pathway is linked to these gene expressions. We examined the mechanisms involving the TLR9 and t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e4f7021e2da19d47da8bffa6496da6a
https://doi.org/10.4049/jimmunol.177.7.4841
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8
A palindromic CpG-containing phosphodiester oligodeoxynucleotide as a mucosal adjuvant stimulates plasmacytoid dendritic cell-mediated T(H)1 immunity
Autor: Ayumi Kubota, Ichiroh Shimada, Saburo Yamamoto, Takasumi Matsuki, Youko Osawa, Eri Murata, Satomi Horiguchi, Takako Komiya, Jun-ichi Maeyama, Fumiko Suzuki, Masanori Isaka, Hisakazu Takatsuka, Sumiko Iho, Harukazu Kitagawa
Publikováno v: PLoS ONE, Vol 9, Iss 2, p e88846 (2014)
PLoS ONE
Background CpG oligodeoxynucleotides (ODNs), resembling bacterial DNA, are currently tested in clinical trials as vaccine adjuvants. They have the nuclease-resistant phosphorothioate bond; the immune responses elicited differ according to the CpG ODN
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76413f9eb526434ee7570ce58ca34c0d
http://europepmc.org/articles/PMC3933336?pdf=render
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