Výsledky vyhledávání - "Youko, Kubuki"

A Case of Cutaneous Type of Adult T-cell Leukemia/Lymphoma Treated with Multiple Modalities

Autor: Nagako Horikawa, Mitsuru Setoyama, Youko Kubuki, Kousuke Mochida, Masahiro Amano, Yukichika Ishii

Publikováno v: Nishi Nihon Hifuka. 73:362-367

54歳，女性。初診の3ヵ月前に体幹および四肢小結節を自覚，小結節は自然消退，新生を繰り返した。病理組織学的にはPautrier微小膿瘍を伴い，真皮上層に異型性を有するリンパ球様細胞�

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4e58e879d9ce69d28f5e13aa821106b9
https://doi.org/10.2336/nishinihonhifu.73.362

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Absence of gain-of-function JAK1 and JAK3 mutations in adult T cell leukemia/lymphoma

Autor: Kouichi Maeda, Tomonori Hidaka, Yasuhiro Taniguchi, Takuro Kameda, Kenji Nagata, Kotaro Shide, Haruko Shimoda, Keiko Katayose, Takuya Matsunaga, Masaaki Sekine, Kazuya Shimoda, A. Kamiunntenn, Youko Kubuki

Publikováno v: International Journal of Hematology. 92:320-325

Janus kinase 1 (JAK1) and JAK3 plays a critical role in lymphocyte proliferation and differentiation. Somatic JAK1 mutations are found in 18% of adult precursor T acute lymphoblastic leukemias and somatic JAK3 mutations are found in 3.3% of cutaneous

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f805ede9f5391f613d52a12d24b2891
https://doi.org/10.1007/s12185-010-0653-2

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The impact of cytogenetic abnormalities on the prognosis of primary myelofibrosis: a prospective survey of 202 cases in Japan

Autor: Katsuto Takenaka, Kenji Nagata, Takurou Kameda, Takashi Okamura, Koichi Akashi, Keiya Ozawa, Mine Harada, Kazuya Shimoda, Kotaro Shide, Yoshiyuki Niho, Keiko Toyama, Hideaki Mizoguchi, Tomonori Hidaka, Youko Kubuki, Mitsuhiro Omine, Haruko Shimoda, Keiko Katayose

Publikováno v: European Journal of Haematology. 83:328-333

Cytogenetic abnormalities were often observed in primary myelofibrosis patients. The presence of specific cytogenetic abnormalities, such as sole abnormalities of chromosome 13q-, 20q-, or -7/7q-, is reported to have the influence on the prognosis of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4719c0e92aba9883dc8d339fcba29070
https://doi.org/10.1111/j.1600-0609.2009.01298.x

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Development of ET, primary myelofibrosis and PV in mice expressing JAK2 V617F

Autor: Takashi Kumano, Takuro Kameda, Kotaro Shide, Satoru Hasuike, Kouichi Ohshima, Youko Kubuki, Hiroo Abe, Kazunori Kusumoto, Kenji Nagata, Tadashi Matsuda, Haruko Shimoda, Keiko Katayose, Kennosuke Karube, Kazuya Shimoda, Katsuto Takenaka, Yoshihiro Tahara, Seido Oku, Mine Harada

Publikováno v: Leukemia. 22:87-95

An acquired JAK2 V617F mutation is found in most patients with polycythemia vera (PV), and about half of patients with essential thrombocythemia (ET) or primary myelofibrosis (PMF). Mice transplanted with bone marrow cells in which JAK2 V617F was ret

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8cb7c14a0d690f6c933a2e10fdc5ed8
https://doi.org/10.1038/sj.leu.2405043

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A case of acute hepatitis A with marked hemophagocytosis in bone marrow

Autor: Hirohito Tsubouchi, Youko Kubuki, Masaaki Onaga, Tetsuya Nishimagi, Katsuhiro Hayashi, Hirohumi Uto, Kenji Nagata, Shuichi Hirono

Publikováno v: Hepatology Research. 17:205-211

A previously well 18-year-old female was referred to our hospital because of abnormalities of blood biochemistry and slight jaundice. Because serum aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels were elevated more than 600

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d63da0425329b719cb57426c66cb5eb7
https://doi.org/10.1016/s1386-6346(99)00076-5

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TET2 is essential for survival and hematopoietic stem cell homeostasis

Publikováno v: Leukemia. 26(10)

Ten-Eleven-Translocation 2 (TET2) is an enzyme that catalyzes the conversion of 5-methylcytosine into 5-hydroxymethylcytosine (5-hmC) and thereby alters the epigenetic state of DNA; somatic loss-of-function mutations of TET2 are frequently observed i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bae16cd997b833b373465c106efce031
https://pubmed.ncbi.nlm.nih.gov/22469782

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Clinical significance of CADM1/TSLC1/IgSF4 expression in adult T-cell leukemia/lymphoma

Autor: Shingo Nakahata, A Goto, Yusuke Saito, N Takamatsu, Toshiyuki Shiraga, Kouichi Maeda, Atae Utsunomiya, Youko Kubuki, Gene Kurosawa, Toshihiko Hidaka, Yujiro Asada, Kosuke Marutsuka, Kinta Hatakeyama, Kazuhiro Morishita, Yoshinori Ukai, Kazuya Shimoda, Akihiko Okayama

Publikováno v: Leukemia. 26(6)

Cell adhesion molecule 1 (CADM1/TSLC1) was recently identified as a novel cell surface marker for adult T-cell leukemia/lymphoma (ATLL). In this study, we developed various antibodies as diagnostic tools to identify CADM1-positive ATLL leukemia cells

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5105d635fb146cda7e825c2deff293b6
https://pubmed.ncbi.nlm.nih.gov/22289924

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[Infection control for the treatment of hematological malignancies: a survey of the Kyushu Hematology Organization for Treatment Study Group (K-HOT)]

Publikováno v: [Rinsho ketsueki] The Japanese journal of clinical hematology. 44(7)

The Kyushu Hematology Organization for Treatment Study Group (K-HOT) consisted of 22 institutions specializing in hematology in Kyushu. This study is aimed at reviewing the daily practice of infection control for the treatment of hematological malign

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6177a02052fc8e1cb4a82edb70ea5b36
https://pubmed.ncbi.nlm.nih.gov/12931571

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