Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Youjun Chu"'
Autor:
Changwen Wang, Meng Sun, Chunxuan Shao, Lisa Schlicker, Yue Zhuo, Yassin Harim, Tianping Peng, Weili Tian, Nadja Stöffler, Martin Schneider, Dominic Helm, Youjun Chu, Beibei Fu, Xiaoliang Jin, Jan-Philipp Mallm, Moritz Mall, Yonghe Wu, Almut Schulze, Hai-Kun Liu
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-21 (2024)
Abstract Recent advances in the genomics of glioblastoma (GBM) led to the introduction of molecular neuropathology but failed to translate into treatment improvement. This is largely attributed to the genetic and phenotypic heterogeneity of GBM, whic
Externí odkaz:
https://doaj.org/article/d63afc60087d40eba8fc806d9ff1af6b
Autor:
Liang Xu, Andrea Carrer, Francesco Zonta, Zhihu Qu, Peixiang Ma, Sheng Li, Federico Ceriani, Damiano Buratto, Giulia Crispino, Veronica Zorzi, Gaia Ziraldo, Francesca Bruno, Chiara Nardin, Chiara Peres, Flavia Mazzarda, Anna M. Salvatore, Marcello Raspa, Ferdinando Scavizzi, Youjun Chu, Sichun Xie, Xuemei Yang, Jun Liao, Xiao Liu, Wei Wang, Shanshan Wang, Guang Yang, Richard A. Lerner, Fabio Mammano
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 10 (2017)
Background: Mutations leading to changes in properties, regulation, or expression of connexin-made channels have been implicated in 28 distinct human hereditary diseases. Eight of these result from variants of connexin 26 (Cx26), a protein critically
Externí odkaz:
https://doaj.org/article/cc3dd804c27e4ae68e8efa44292bdd38
Autor:
Yu Li, Flavia Mazzarda, Lili Liu, Damiano Buratto, Francesco Zonta, Richard A. Lerner, Fabio Mammano, Marcello Raspa, Francesco Chiani, Youjun Chu, Gaia Ziraldo, Min Qiang, Ferdinando Scavizzi, Xiaojie Shi, Yaru Shi, Yuanyuan Kuang, Anna Maria Salvatore, Chiara Nardin, Guang Yang, Veronica Zorzi, Chiara Peres
Publikováno v:
EBioMedicine
Background Numerous currently incurable human diseases have been causally linked to mutations in connexin (Cx) genes. In several instances, pathological mutations generate abnormally active Cx hemichannels, referred to also as "leaky" hemichannels. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5a79dd8ad793aeabb5d22c5e0801622
http://hdl.handle.net/11577/3346805
http://hdl.handle.net/11577/3346805
Autor:
Xuebiao Yao, Qi Wang, Yun Zhao, Peng R Chen, Youjun Chu, Guowei Fang, Fei Mo, Wenwen Wang, Zhen Dou, Ruoying Yu, Ping Gui, Jun Cao, Shihao Du, Lingluo Chu, Mahboob Ali, Huihui Wu, Xinjiao Gao, Jianye Zang, Jianyu Wang, Tarsha Ward, Hazrat Ismail, F.M. Yang, Xing Liu, Mingliang Ye
Publikováno v:
Journal of Molecular Cell Biology
Faithful segregation of mitotic chromosomes requires bi-orientation of sister chromatids, which relies on the sensing of correct attachments between spindle microtubules and kinetochores. Although the mechanisms underlying PLK1 activation have been e
Autor:
Ying Han, Hongtao Yu, Xiaoai Lu, Wenshu Li, Fengxia Zhang, Jun Liao, Youjun Chu, Hongdan Yang, Piliang Hao, Jungseog Kang, Ching Jung Huang
Publikováno v:
Molecular Biology of the Cell
Accurate partitioning of chromosomes during mitosis is essential for genetic stability and requires the assembly of the dynamic mitotic spindle and proper kinetochore–microtubule attachment. The spindle assembly checkpoint (SAC) monitors the incomp
Autor:
Xinjiao Gao, Saima Akram, Xing Liu, Wei Peng, Ruijun Tian, Dong Wang, Xuebiao Yao, Chunli Wang, Ming Wang, Maomao Yan, Ping He, Hanfa Zou, Zhen Dou, Hadiyah-Nichole Green, Hequan Duan, Youjun Chu, Jiajia Zhou, Gregory Barrett, Fangjun Wang, Wenwen Wang
Publikováno v:
The Journal of biological chemistry. 291(40)
During cell division, accurate chromosome segregation is tightly regulated by Polo-like kinase 1 (PLK1) and opposing activities of Aurora B kinase and protein phosphatase 1 (PP1). However, the regulatory mechanisms underlying the aforementioned hiera
Autor:
Yuejia Huang, Xuebiao Yao, Liangyu Zhang, Yuwen Ke, Dongmei Wang, Phil Y. Yao, Wenwen Wang, Youjun Chu, Zhikai Wang, Xia Ding
Publikováno v:
Journal of Molecular Cell Biology. 3:260-267
During cell division, chromosome segregation is orchestrated by the interaction of spindle microtubules with the centromere. Accurate attachment of spindle microtubules to kinetochore requires the chromosomal passenger of Aurora B kinase complex with
Autor:
Xin Wang, Zhilei Zhou, Jianfei Zhao, Xiaomin Song, Youjun Chu, Yingying Jia, Lin Li, Zhubing Shi, Haofei Miao, Sichun Xie
Publikováno v:
The Journal of biological chemistry. 289(49)
Previously, we have identified Caprin-2 as a new regulator in canonical Wnt signaling through a mechanism of facilitating LRP5/6 phosphorylation; moreover, we found that its C-terminal C1q-related domain (Cap2_CRD) is required for this process. Here,
Autor:
Liangyu Zhang, Zhen Dou, Kai Yuan, Xuebiao Yao, Hengyi Shao, Minerva Garcia-Barrio, Xing Liu, Yuejia Huang, Youjun Chu, Changjiang Jin
Publikováno v:
Scientific Reports
Chromosome segregation in mitosis is orchestrated by the dynamic interactions between the kinetochore and spindle microtubules. The microtubule depolymerase mitotic centromere-associated kinesin (MCAK) is a key regulator for an accurate kinetochore-m
Autor:
Jianyu Wang, Huijuan Yu, Tarsha Ward, Donald L. Hill, Lifang Liu, Zhikai Wang, Peng Xia, Kai Jiang, Xuebiao Yao, Youjun Chu, Tongge Zhu, Xing Liu, Xiwei Wang, Yuejia Huang, Maomao Yan, Ming Wang
Publikováno v:
The Journal of biological chemistry. 288(22)
The microtubule cytoskeleton network orchestrates cellular dynamics and chromosome stability in mitosis. Although tubulin acetylation is essential for cellular plasticity, it has remained elusive how kinetochore microtubule plus-end dynamics are regu