Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Youjia Tian"'
Autor:
Yi Zhu, Xin-Xin Chai, Yuanyuan Zhao, Qiao Feng, Rong Dong, Meng-Jie Shi, Jiang Zhou, Yurong Zhao, Junxuan Peng, Youjia Tian, Guangdi Chen, Chi Luo, Jinghao Sheng
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 259, Iss , Pp 115040- (2023)
Exposure to the toxic metal cadmium (Cd) is a well-established risk factor for hepatic inflammation, but it remains unclear how metabolic components, such as different fatty acids (FAs), interact with Cd to influence this process. Understanding these
Externí odkaz:
https://doaj.org/article/0e2347b530ff4d448489da83b96f055c
Autor:
Youjia Tian, Jiang Zhou, Xinxin Chai, Zejun Ping, Yurong Zhao, Xin Xu, Chi Luo, Jinghao Sheng
Publikováno v:
Cancers, Vol 15, Iss 18, p 4505 (2023)
As one of the most common malignant tumors, melanoma is a serious threat to human health. More than half of melanoma patients have a BRAF mutation, and 90% of them have a BRAF(V600E) mutation. There is a targeted therapy for patients using a BRAF(V60
Externí odkaz:
https://doaj.org/article/144c50a712334d1dbe0bf678f3e5bff4
Autor:
Yi Zhu, Yuanyuan Zhao, Xin-Xin Chai, Jiang Zhou, Meng-Jie Shi, Yurong Zhao, Youjia Tian, Xu-Meng Wang, Tian-Xing Ying, Qiao Feng, Jinghao Sheng, Chi Luo
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 233, Iss , Pp 113306- (2022)
Exposure to cadmium (Cd), a toxic metal, is epidemiologically linked to nonalcoholic steatohepatitis (NASH) in humans. However, the role of Cd in NASH remains to be fully elucidated. This study employed a novel murine NASH model to investigate the ef
Externí odkaz:
https://doaj.org/article/7ce43bd57c174c05a27a13002339532f
Autor:
Wanzhen Jiang, Mengliu Zeng, Zhenzhen Cao, Zhipei Liu, Jie Hao, Peipei Zhang, Youjia Tian, Peihua Zhang, Jihua Ma
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
Icariin, a flavonoid monomer from Herba Epimedii, has confirmed pharmacological and biological effects. However, its effects on arrhythmias and cardiac electrophysiology remain unclear. Here we investigate the effects of icariin on ion currents and a
Externí odkaz:
https://doaj.org/article/1e6164d925b14d5dad68a543d3a8dd67
Autor:
Ze-fu Zhang, Youjia Tian, Liangkun Hu, Peihua Zhang, Jihua Ma, Yan-Yan Yang, Shi-Han Li, Peipei Zhang
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 473:1315-1327
Cardiac alternans closely linked to calcium dysregulation is a crucial risk factor for fatal arrhythmia causing especially sudden death. Calcium overload is well-known to activate Ca2+-dependent protein kinase C (PKC); however, the effects of PKC on
Autor:
Yi Zhu, Yuanyuan Zhao, Xin-Xin Chai, Jiang Zhou, Meng-Jie Shi, Yurong Zhao, Youjia Tian, Xu-Meng Wang, Tian-Xing Ying, Qiao Feng, Jinghao Sheng, Chi Luo
Publikováno v:
Ecotoxicology and environmental safety. 233
Exposure to cadmium (Cd), a toxic metal, is epidemiologically linked to nonalcoholic steatohepatitis (NASH) in humans. However, the role of Cd in NASH remains to be fully elucidated. This study employed a novel murine NASH model to investigate the ef
Autor:
Zhenzhen Cao, Jihua Ma, Lv Song, Jie Hao, Peipei Zhang, Youjia Tian, Zhipei Liu, Peihua Zhang, Antao Luo
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Ginsenoside Rb1 exerts its pharmacological action by regulating sodium, potassium and calcium ion channels in the membranes of nerve cells. These ion channels are also present in cardiomyocytes, but no studies have been reported to date regarding the
Autor:
Zhenzhen Cao, Zhipei Liu, Peipei Zhang, Peihua Zhang, Yu-zhong Jia, Jihua Ma, Lv Song, Youjia Tian
Publikováno v:
Life sciences. 244
Aims Detect the antiarrhythmic effect of crotonoside (Cro). Main methods We used whole-cell patch-clamp techniques to detect the effects of Cro on action potentials (APs) and transmembrane ion currents in isolated rabbit left ventricular myocytes. We
Autor:
Zuchao Cai, Youjia Tian, Shue Wang, Yue Luo, Simon N. Powell, Guochao Liu, Xiaowei Wang, Gongshe Guo, Hui Wang, Zhujun Tian, Zhihui Feng, Fengmei Zhang
Publikováno v:
DNA Repair. 58:1-12
It was reported that valproic acid (VPA, a histone deacetylase inhibitor) can sensitize cancer cells to hydroxyurea (HU, a ribonucleotide reductase inhibitor) for chemotherapy, although the mechanism of VPA-induced HU sensitization is unclear. In thi
Autor:
Peipei Zhang, Quankui Zhou, Jie Hao, Liangkun Hu, Zhijing Song, Zhenzhen Cao, Zhipei Liu, Jihua Ma, Peihua Zhang, Youjia Tian
Publikováno v:
Pharmacology. 102(5-6)
Aim: Sodium houttuyfonate (SH), a chemical compound originating from Houttuynia cordata, has been reported to have anti-inflammatory, antibacterial, and antifungal effects, as well as cardioprotective effects. In this study, we investigated the effec