Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Youichi Aizawa"'
Autor:
Yuko Kuramochi, Youichi Aizawa, Takashi Kato, Hitomi Iemura, Nami Nogawa-Kosaka, Takehito Okui, Shun Maekawa, Hironori Nishikawa
Publikováno v:
Journal of Experimental Biology. 215:3087-3095
SUMMARYDiminished erythrocyte count and erythropoiesis have been reported during hypothermia in some ectothermic animals. In this study, the African clawed frog, Xenopus laevis, was used to investigate the cause of hypothermia-induced anemia. We deve
Autor:
Takashi Funatsu, Akihiko Sakamoto, Mai Yamagishi, Youichi Aizawa, Takashi Kato, Takafumi Watanabe
Publikováno v:
Journal of Bioscience and Bioengineering. 105:238-242
Fluorescence labeling of a cytokine at a specific site is required for observing cytokine-receptor interactions in living cells at the single-molecule level. Here, we demonstrated the C-terminus-specific fluorescence labeling of histidine-tagged thro
Autor:
Youichi Aizawa, Susumu Ishii
Publikováno v:
General and Comparative Endocrinology. 132:465-473
Reptilia is the only vertebrate class in which cDNA for the gonadotropin beta subunit precursor molecule has not been cloned. We have isolated the full-length cDNA clone encoding the LH beta subunit precursor molecule and a partial cDNA clone encodin
Autor:
Takehito Okui, Youichi Aizawa, Yuka Yonezuka, Yusuke Yamamoto, Takashi Kato, Kazumichi Nagasawa, Shun Maekawa
Publikováno v:
Cell and tissue research. 353(1)
Erythropoiesis occurs in the African clawed frog, Xenopus laevis and is mediated by erythropoietin (xlEPO), a primary regulator of this process. Previously, we have shown that the xlEPO receptor (xlEPOR), which is expressed by erythroid progenitors t
Autor:
Youichi Aizawa, Yuta Tanizaki, Mizue Meguro, Takashi Kato, Shun Maekawa, Tatsuhisa Sugai, Nami Nogawa-Kosaka, Kazumichi Nagasawa, Ryota Kuroki, Motoyasu Adachi
Publikováno v:
The Journal of experimental biology. 214(Pt 6)
Oxygen is essential for the survival of animals. Red blood cells in the circulation, i.e. peripheral erythrocytes, are responsible for transporting oxygen to tissues. The regulation of erythropoiesis in vertebrates other than mammals is yet to be elu
Autor:
Hiroshi Miyazaki, Takayuki Hirose, Youichi Aizawa, Nobuaki Uehara, Nobuyoshi Kosaka, Nami Nogawa-Kosaka, Norio Komatsu, Takashi Kato, Kazumichi Nagasawa
Publikováno v:
Experimental hematology. 38(5)
Objective Erythropoietin (EPO) and its receptor (EPOR) are key regulators of red blood cell production in mammals and fish. We aimed to investigate the structural and functional conservation of the EPO-EPOR system in amphibian erythropoiesis, using X
Autor:
Nami Nogawa, Yasutaka Maeda, Nobuyoshi Kosaka, Hiroshi Miyazaki, Youichi Aizawa, Takafumi Watanabe, Takashi Kato
Publikováno v:
Journal of biochemistry. 138(2)
The regulation of hematopoiesis in non-mammalian vertebrates is poorly understood. This is partly because the structures and effects of most hematopoietic regulators have not been identified. As a first step towards studies on the key mechanism of he
Publikováno v:
Blood. 114:4563-4563
Abstract 4563 Erythropoietin (EPO) and erythropoietin receptor (EPOR) are primary regulators of erythropoiesis in mammals. In human EPO (huEPO), for example, there are three well-conserved glycosylation sites for N-linked carbohydrates. It is reporte
Publikováno v:
Blood. 114:4577-4577
Abstract 4577 In mammalians, primitive hematopoiesis occurs in yolk sac at early embryonic, and alters to a liver and spleen turning to definitive hematopoiesis at fetal stage. And then, finally, bone marrow becomes a main hematopoietic organ in adul
Autor:
Hiroshi Miyazaki, Nami Nogawa-Kosaka, Youichi Aizawa, Nobuyoshi Kosaka, Hironori Nishikawa, Takashi Kato, Takehito Okui
Publikováno v:
Blood. 110:4057-4057
Recent studies on EPO-EPOR systems in non-mammalian vertebrate including frog and teleost fishes demonstrate extramedullary adult erythropoiesis instead of bone marrow. In adult Xenopus laevis (African clawed frog), an animal model of hepatic erythro