Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Youan Liu"'
Autor:
Lisa Y. Q. Hong, Emily S. H. Yeung, Duc Tin Tran, Veera Ganesh Yerra, Harmandeep Kaur, M. D. Golam Kabir, Suzanne L. Advani, Youan Liu, Sri Nagarjun Batchu, Andrew Advani
Publikováno v:
Disease Models & Mechanisms, Vol 16, Iss 9 (2023)
Externí odkaz:
https://doaj.org/article/9ce26968793046ee9fdc8c7f8ae9040d
Autor:
Veera Ganesh Yerra, Sri Nagarjun Batchu, Harmandeep Kaur, MD Golam Kabir, Youan Liu, Suzanne L. Advani, Duc Tin Tran, Shadi Sadeghian, Phelopater Sedrak, Filio Billia, Uros Kuzmanov, Anthony O. Gramolini, Deema O. Qasrawi, Evgeniy V. Petrotchenko, Christoph H. Borchers, Kim A. Connelly, Andrew Advani
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 9 (2023)
Inflammation promotes adverse ventricular remodeling, a common antecedent of heart failure. Here, we set out to determine how inflammatory cells affect cardiomyocytes in the remodeling heart. Pathogenic cardiac macrophages induced an IFN response in
Externí odkaz:
https://doaj.org/article/0c5911e4a2bf433aac0c14bc3122354f
Autor:
Karina Thieme, Syamantak Majumder, Angela S. Brijmohan, Sri N. Batchu, Bridgit B. Bowskill, Tamadher A. Alghamdi, Suzanne L. Advani, M. Golam Kabir, Youan Liu, Andrew Advani
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract The therapeutic targeting of prostanoid subtype receptors may slow the development of chronic kidney disease (CKD) through mechanisms that are distinct from those of upstream COX inhibition. Here, employing multiple experimental models of CK
Externí odkaz:
https://doaj.org/article/3c7f7c6c5c3f478c808baefc6898c731
Autor:
Sri Nagarjun Batchu, Veera Ganesh Yerra, Youan Liu, Suzanne L. Advani, Thomas Klein, Andrew Advani
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 16, p 5756 (2020)
Despite a similar mechanism of action underlying their glucose-lowering effects in type 2 diabetes, dipeptidyl peptidase-4 (DPP-4) inhibitors have diverse molecular structures, raising the prospect of agent-specific, glucose-independent actions. To e
Externí odkaz:
https://doaj.org/article/a2b971b1fbab4948b79cd3a636332ce5
Autor:
Angela S. Brijmohan, Sri N. Batchu, Syamantak Majumder, Tamadher A. Alghamdi, Karina Thieme, Sarah McGaugh, Youan Liu, Suzanne L. Advani, Bridgit B. Bowskill, M. Golam Kabir, Laurette Geldenhuys, Ferhan S. Siddiqi, Andrew Advani
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
To contend with the deleterious effects of accumulating misfolded protein aggregates or damaged organelles cells rely on a system of quality control processes, among them the autophagy-lysosome pathway. This pathway is itself controlled by a master r
Externí odkaz:
https://doaj.org/article/c86c2dcce1284f3e9217269d289233bf
Autor:
Harmandeep Kaur, Veera Ganesh Yerra, Sri Nagarjun Batchu, Duc Tin Tran, M. D. Golam Kabir, Youan Liu, Suzanne L. Advani, Phelopater Sedrak, Laurette Geldenhuys, Karthik K. Tennankore, Penelope Poyah, Ferhan S. Siddiqi, Andrew Advani
Publikováno v:
British Journal of Pharmacology.
Autor:
Suzanne L. Advani, Youan Liu, Veera Ganesh Yerra, Ferhan S. Siddiqi, Sri N. Batchu, Andrew Advani, Golam Kabir, Kim A. Connelly
Publikováno v:
Cardiovascular Drugs and Therapy. 36:619-632
Although the cardioprotective benefits of sodium-glucose cotransporter 2 (SGLT2) inhibitors are now widely appreciated, the mechanisms underlying these benefits remain unresolved. Tumor necrosis factor receptor superfamily member 12a (Tnfrsf12a) is a
Autor:
Veera Ganesh Yerra, Youan Liu, Andrew Advani, M. Golam Kabir, Suzanne L. Advani, Harmandeep Kaur, Sri N. Batchu, Thomas Klein
Publikováno v:
Diabetes. 70:759-771
The causes of the increased risk of severe coronavirus disease 2019 (COVID-19) in people with diabetes are unclear. It has been speculated that renin-angiotensin system (RAS) blockers may promote COVID-19 by increasing ACE2, which severe acute respir
Autor:
Gedaliah Farber, Liyong Zhang, Youan Liu, Dana J. Philpott, Fayez Dawood, Yena Oh, Kyoung-Han Kim, Alan Valaperti, Benjamin H. Rotstein, Peter P. Liu, Guo Hua Li, David Smyth, Mark Moon, Georges N. Kanaan, Wenbin Liang, Han-Bin Lin, Mary-Ellen Harper, Kotaro Naito
Publikováno v:
Circulation
Background: Cardiac hypertrophy is a key biological response to injurious stresses such as pressure overload and, when excessive, can lead to heart failure. Innate immune activation by danger signals, through intracellular pattern recognition recepto
Autor:
Veera Ganesh, Yerra, Sri Nagarjun, Batchu, Golam, Kabir, Suzanne L, Advani, Youan, Liu, Ferhan S, Siddiqi, Kim A, Connelly, Andrew, Advani
Publikováno v:
Cardiovascular drugs and therapy. 36(4)
Although the cardioprotective benefits of sodium-glucose cotransporter 2 (SGLT2) inhibitors are now widely appreciated, the mechanisms underlying these benefits remain unresolved. Tumor necrosis factor receptor superfamily member 12a (Tnfrsf12a) is a