Zobrazeno 1 - 10
of 86
pro vyhledávání: '"You-You Zhang"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Although an increasing number of disease genes have been identified, the exact cellular mechanisms of retinitis pigmentosa (RP) remain largely unclear. Retinal organoids (ROs) derived from the induced pluripotent stem cells (iPSCs) of patients provid
Externí odkaz:
https://doaj.org/article/9a14ec491e974854968ce64c5b8737fc
Autor:
Chang-Jun Zhang, Yan-Ping Li, Kun-Chao Wu, Yaru Zhang, Hui Liu, Jianzhong Su, Zi-Qi Hua, Zi-Bing Jin, You-You Zhang, Yan Zhang, Fulong Yu
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance As a genetic malignancy, retinoblastoma (Rb) is caused by RB1 mutations; however, its developmental origin and drug agents for human Rb remain largely unexplored. Here we describe an innovative Rb organoid model derived from human embryo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b04d3372c8363ae66c32ab2a1698855
https://doi.org/10.1073/pnas.2011780117
https://doi.org/10.1073/pnas.2011780117
Publikováno v:
2021 IEEE 14th International Conference on ASIC (ASICON).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fca72baf86d0b0359d1eeda333cf244c
https://doi.org/10.1109/asicon52560.2021.9620529
https://doi.org/10.1109/asicon52560.2021.9620529
Autor:
Ji-Neng Lv, Jianzhong Su, Chong Chen, Zi-Bing Jin, Yan-Ping Li, You-You Zhang, Jia Qu, Fulong Yu, Fan Lu, Yan Zhang, Kun-Chao Wu, Fang Han, Si-Qian Jin, Chang-Jun Zhang, Hui Liu, Qiang Lin, Zi-Qi Hua
Publikováno v:
SSRN Electronic Journal.
Retinoblastoma (Rb) is the most prevalent intraocular malignant tumour in children with survival rate less than 30% globally. Its developmental origin and drug agents remain largely unexplored. Here, we developed the first organoid Rb model derived f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d69890e1d5310fed2d37e24f4d47216b
https://doi.org/10.2139/ssrn.3464655
https://doi.org/10.2139/ssrn.3464655
Autor:
Angelos Dassios, You You Zhang
Publikováno v:
Finance and Stochastics. 20:773-804
We study the joint law of Parisian time and hitting time of a drifted Brownian motion by using a three-state semi-Markov model, obtained through perturbation. We obtain a martingale, to which we can apply the optional sampling theorem and derive the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d12efcc5a042bc59b41bf26d6c4cb961
https://doi.org/10.1007/s00780-016-0302-6
https://doi.org/10.1007/s00780-016-0302-6
Autor:
Yang Zhang, Hao Zhu, Yan Jiang, Qi Qun Tang, Li Qi Xie, Pengyuan Yang, Hao Jie Lu, Xiaohui Liu, You You Zhang, Liang Guo
Publikováno v:
Journal of Proteome Research. 13:1307-1314
Mitotic clonal expansion (MCE) is one of the important events taking place at the early stage during 3T3-L1 adipocyte differentiation. To investigate the mechanism underlying this process, we carried out a temporal proteomic analysis to profile the d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31e3cf67232917d87d1a8c079db25571
https://doi.org/10.1021/pr401292p
https://doi.org/10.1021/pr401292p
Autor:
Yuan Liu, Zhi Chun Zhang, Qi Qun Tang, Shu Wen Qian, Hai Yan Huang, Liang Guo, Yan Tang, Xi Li, You You Zhang
Publikováno v:
Journal of Biological Chemistry. 288:8222-8230
BMP4 has been shown to induce C3H10T1/2 pluripotent stem cells to commit to adipocyte lineage. In addition to several proteins identified, microRNAs also play a critical role in the process. In this study, we identified microRNA-140 (miR-140) as a di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::744176b3e219c6620eace72c44f6eaf4
https://doi.org/10.1074/jbc.m112.426163
https://doi.org/10.1074/jbc.m112.426163
Publikováno v:
Advanced Materials Research. :1800-1803
Demand response (DR) has become an important part of smart grid, mainly for modulating load curve, emergency treatment, balancing the demand and supply of power system. The features of smart grid-self healing and interactive-give the new meaning to D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6dd09f56af00d890a8873927e5c207d6
https://doi.org/10.4028/www.scientific.net/amr.614-615.1800
https://doi.org/10.4028/www.scientific.net/amr.614-615.1800
Autor:
Qun He, Liang Guo, Chun Gu Ma, Yuan Liu, Shu Wen Qian, Xi Li, Hai Yan Huang, You You Zhang, Qi Qun Tang
Publikováno v:
Molecular Endocrinology. 26:798-808
Runx2, a runt-related transcriptional factor family member, is involved in the regulation of osteoblast differentiation. Interestingly, it is abundant in growth-arrested 3T3-L1 preadipocytes and was dramatically down-regulated during adipocyte differ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cafafdb8ee59cc0fdfd7ffd290ec0b46
https://doi.org/10.1210/me.2011-1287
https://doi.org/10.1210/me.2011-1287
Publikováno v:
Biochemical and Biophysical Research Communications. 419:550-555
CCAAT/enhancer-binding protein (C/EBP) β plays an important role in proliferation and differentiation of 3T3-L1 preadipocytes. C/EBPβ is sequentially phosphorylated during the 3T3-L1 adipocyte differentiation program, first by MAPK/Cyclin A/cdk2 on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2176fec6b7eea3366a47bb25643d741
https://doi.org/10.1016/j.bbrc.2012.02.058
https://doi.org/10.1016/j.bbrc.2012.02.058