Zobrazeno 1 - 7
of 7
pro vyhledávání: '"You-You Yan"'
Publikováno v:
Chinese Medical Journal, Vol 129, Iss 22, Pp 2676-2682 (2016)
Background:β-adrenoceptors play a crucial regulatory role in blood vessel endothelial cells. Isoprenaline (ISO, a β-adrenergic agonist) has been reported to promote angiogenesis through upregulation of vascular endothelial growth factor (VEGF) expr
Externí odkaz:
https://doaj.org/article/2f459bd3efa34bf880acff70c3324975
Publikováno v:
Chinese Medical Journal, Vol 129, Iss 23, Pp 2786-2791 (2016)
Background: Percutaneous coronary intervention (PCI) causes endothelial damage, resulting in an inflammatory response with elevation of markers such as high-sensitive C-reactive protein (hs-CRP) and vascular cell adhesion molecule-1 (VCAM-1), which a
Externí odkaz:
https://doaj.org/article/7cb44155fd154c3c8d8fd24c6db08d0c
Publikováno v:
Acta Pharmacologica Sinica
Natural compound valepotriate exhibits inhibitory activity against a number of cancers, but the effect of valepotriate against pancreatic cancer is unclear, and the structure–activity relationship of valepotriate has not been characterized. In this
Autor:
Bo Zhang, You‐you Yan, Yang‐qin Gu, Fei Teng, Xu Lin, Xing‐lu Zhou, Jin‐xin Che, Xiao‐wu Dong, Li‐xin Zhou, Neng‐ming Lin
Publikováno v:
Journal of Cellular and Molecular Medicine
Pancreatic cancer is one of the most notorious diseases for being asymptomatic at early stage and high mortality rate thereafter. However, either chemotherapy or targeted therapy has rarely achieved success in recent clinical trials for pancreatic ca
Autor:
Gang Cheng, Xiao‐Bing Mei, You‐You Yan, Jing Chen, Bo Zhang, Jia Li, Xiao‐Wu Dong, Neng‐Ming Lin, Yu‐Bo Zhou
Publikováno v:
Archiv der Pharmazie. 352(7)
NF-κB inducing kinase (NIK) is a key regulator in the noncanonical nuclear factor κB cells (NF-κB) signaling pathway. Dysregulation of NIK is often related with autoimmune disorders and malignancies. However, the number of reported NIK inhibitors
Autor:
Dan, Zhang, Bo, Zhang, Li-Xin, Zhou, Jun, Zhao, You-You, Yan, Yang-Ling, Li, Jian-Mei, Zeng, Lin-Ling, Wang, Bo, Yang, Neng-Ming, Lin
Publikováno v:
Acta Pharmacologica Sinica
Aim: Deacetylisovaltratum (DI) is isolated from the traditional Chinese herbal medicine Patrinia heterophylla Bunge, which exhibits anti-cancer activity. Here, we investigated the effects of DI on human gastric carcinoma cell lines in vitro and eluci
Publikováno v:
Chinese Chemical Letters. 23:1165-1168
A new sesquiterpenoid, 1 β ,5 α -guaiane-4 β ,10 α -diol-6-one ( 1 ), was isolated from 70% EtOH extract of the rhizomes of Acorus calamus . The structure was determined on spectroscopic methods, especially 2D NMR techniques. The absolute configu