Zobrazeno 1 - 10
of 73
pro vyhledávání: '"You-Tzung Chen"'
Autor:
Shih-Yun Chen, Tse-En Wang, Wei-Yun Lee, Ya-Yi Yang, Hong-Chun Lai, Fuko Matsuda, Haruhiko Kosek, You-Tzung Chen, Sheng-Hsiang Li, Pei-Shiue Tsai
Publikováno v:
Journal of Ovarian Research, Vol 17, Iss 1, Pp 1-13 (2024)
Abstract Background Quiescin sulfhydryl oxidase 2 (QSOX2) is a flavin adenine dinucleotide-dependent sulfhydryl oxidase that is known to be involved in protein folding, cell growth regulation, and redox state modification through oxidative activities
Externí odkaz:
https://doaj.org/article/e97a3d438afd49a59d8b4328358b2c73
Autor:
Yen-Hui Chan, Cheng-Yu Tsai, Chang-Han Ho, Ying-Chang Lu, Pei-Hsuan Lin, Ta-Ching Chen, You-Tzung Chen, Cheng-Yen Huang, Tien-Chen Liu, Chuan-Jen Hsu, Chen-Chi Wu
Publikováno v:
Stem Cell Research, Vol 69, Iss , Pp 103068- (2023)
Pathogenic variants of the WFS1 gene can cause recessive-inherited Wolfram syndrome or dominant-inherited Wolfram-like syndrome with optic atrophy and hearing impairment. Using the Sendai virus delivery system, we generated induced pluripotent stem c
Externí odkaz:
https://doaj.org/article/49e3de1a76214919a0162b874dcd28f8
Autor:
Kuo-Hsuan Chang, Cheng-Yen Huang, Chih-Hsin Ou-Yang, Chang-Han Ho, Han-Yi Lin, Chia-Lang Hsu, You-Tzung Chen, Yu-Chi Chou, Yi-Jing Chen, Ying Chen, Jia-Li Lin, Ji-Kuan Wang, Pei-Wen Lin, Ying-Ru Lin, Miao-Hsia Lin, Chi-Kang Tseng, Chin-Hsien Lin
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-18 (2021)
Abstract Background The c.G6055A (p.G2019S) mutation in leucine-rich repeat kinase 2 (LRRK2) is the most prevalent genetic cause of Parkinson’s disease (PD). CRISPR/Cas9-mediated genome editing by homology-directed repair (HDR) has been applied to
Externí odkaz:
https://doaj.org/article/bc881b164425452fba2c024c95eb8485
Autor:
Yen-Hui Chan, Chang-Han Ho, Cheng-Yu Tsai, Ying-Chang Lu, Pei-Hsuan Lin, Ta-Ching Chen, You-Tzung Chen, Cheng-Yen Huang, Tien-Chen Liu, Chuan-Jen Hsu, Chen-Chi Wu
Publikováno v:
Stem Cell Research, Vol 64, Iss , Pp 102903- (2022)
Pathogenic variants of OPA1 have been associated with autosomal dominant optic atrophy (DOA), leading to optic, auditory, and other sensorineural neuropathies and myopathies. Using the Sendai virus delivery system, we generated induced pluripotent st
Externí odkaz:
https://doaj.org/article/44d5b4e1264b482692fd96e5abebf0b1
Autor:
Yen-Hui Chan, Yen-Fu Cheng, You-Tzung Chen, Cheng-Yen Huang, Chin-Hsien Lin, Chin-Ju Hu, Ying-Chang Lu, Chen-Chi Wu, Chuan-Jen Hsu
Publikováno v:
Stem Cell Research, Vol 33, Iss , Pp 51-55 (2018)
Recessive mutations in the GJB2 gene are the most common genetic cause of hearing loss in humans. By using the Sendai-virus delivery system, we generated induced pluripotent stem cells (iPSCs) from the peripheral blood mononuclear cells of a female p
Externí odkaz:
https://doaj.org/article/368e9d8d3b314b279a6e044737d791c6
Publikováno v:
Data in Brief, Vol 15, Iss , Pp 545-561 (2017)
Tumor satellite formation is an indicator of cancer invasiveness and correlates with recurrence, metastasis, and poorer prognosis. By analyzing pathological specimens, tumor satellites formed at the tumor-host interface reflect the phenomena of epith
Externí odkaz:
https://doaj.org/article/49475910b0e043feae796e4dd1936633
Autor:
Chun-Yu Chen, I-Shing Yu, Chen-Hsueh Pai, Chien-Yu Lin, Shu-Rung Lin, You-Tzung Chen, Shu-Wha Lin
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0219221 (2019)
Cul4b-null (Cul4bΔ/Y) mice undergo growth arrest and degeneration during the early embryonic stages and die at E9.5. The pathogenic causes of this lethality remain incompletely characterized. However, it has been hypothesized that the loss of Cul4b
Externí odkaz:
https://doaj.org/article/66a7ee17e4874d8db8400b9c31f6f194
Autor:
Ming-Shian Tsai, Meng-Larn Lee, Chun-Yun Chang, Hsiang-Hsuan Fan, I-Shing Yu, You-Tzung Chen, Jhih-Yi You, Chun-Yu Chen, Fang-Chia Chang, Jane H. Hsiao, Olga Khorkova, Horng-Huei Liou, Yuchio Yanagawa, Li-Jen Lee, Shu-Wha Lin
Publikováno v:
Neurobiology of Disease, Vol 77, Iss , Pp 35-48 (2015)
Dravet syndrome (DS) is characterized by severe infant-onset myoclonic epilepsy along with delayed psychomotor development and heightened premature mortality. A primary monogenic cause is mutation of the SCN1A gene, which encodes the voltage-gated so
Externí odkaz:
https://doaj.org/article/1c02147f797648a2b604654ad1313ea0
Autor:
Jin-Bon Hong, Fu-Ju Chou, Amy T Ku, Hsiang-Hsuan Fan, Tung-Lung Lee, Yung-Hsin Huang, Tsung-Lin Yang, I-Chang Su, I-Shing Yu, Shu-Wha Lin, Chung-Liang Chien, Hong-Nerng Ho, You-Tzung Chen
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89396 (2014)
PiggyBac is a prevalent transposon system used to deliver transgenes and functionally explore the mammalian untouched genomic territory. The important features of piggyBac transposon are the relatively low insertion site preference and the ability of
Externí odkaz:
https://doaj.org/article/d8a43facd1b545b5a5f3faa0377d988e
Autor:
You-Tzung Chen, Ming-Shian Tsai, Tsung-Lin Yang, Amy Tsu Ku, Ke-Han Huang, Cheng-Yen Huang, Fu-Ju Chou, Hsiang-Hsuan Fan, Jin-Bon Hong, Shuo-Ting Yen, Wei-Le Wang, Chang-Ching Lin, Yu-Chen Hsu, Kang-Yi Su, I-Chang Su, Chuan-Wei Jang, Richard R Behringer, Rebecca Favaro, Silvia K Nicolis, Chung-Liang Chien, Shu-Wha Lin, I-Shing Yu
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e46171 (2012)
Green fluorescent protein (GFP) and its derivatives are the most widely used molecular reporters for live cell imagining. The development of organelle-specific fusion fluorescent proteins improves the labeling resolution to a higher level. Here we ge
Externí odkaz:
https://doaj.org/article/a20ca3faae154d9386b89f5a97aa8e52