Zobrazeno 1 - 6 of 6 pro vyhledávání: '"You-Tien Tsai"'
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Deep Learning-Assisted Repurposing of Plant Compounds for Treating Vascular Calcification: An In Silico Study with Experimental Validation
Autor: Chia-Ter Chao, You-Tien Tsai, Wen-Ting Lee, Hsiang-Yuan Yeh, Chih-Kang Chiang
Publikováno v: Oxidative Medicine and Cellular Longevity, Vol 2022 (2022)
Oxidative Medicine and Cellular Longevity
Background. Vascular calcification (VC) constitutes subclinical vascular burden and increases cardiovascular mortality. Effective therapeutics for VC remains to be procured. We aimed to use a deep learning-based strategy to screen and uncover plant c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::419905a76f53b633d12018ab9ab10b2c
https://doi.org/10.1155/2022/4378413
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3
Natural and non-natural antioxidative compounds: potential candidates for treatment of vascular calcification
Autor: Tzu-Hang Yuan, Hsiang-Yuan Yeh, Pei-Huan Chuang, Huei-Wen Chen, You-Tien Tsai, Chia-Ter Chao, Jenq-Wen Huang
Publikováno v: Cell Death Discovery, Vol 5, Iss 1, Pp 1-11 (2019)
Cell Death Discovery
Vascular calcification (VC) is highly prevalent in patients with advanced age, or those with chronic kidney disease and diabetes, accounting for substantial global cardiovascular burden. The pathophysiology of VC involves active mineral deposition by
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4535167bf94c9dada58b0023a30ae514
http://link.springer.com/article/10.1038/s41420-019-0225-z
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4
Superoxide Dismutase 2 (SOD2) in Vascular Calcification: A Focus on Vascular Smooth Muscle Cells, Calcification Pathogenesis, and Therapeutic Strategies
Autor: Chia-Ter Chao, Chih-Kang Chiang, You-Tien Tsai, Hsiang-Yuan Yeh
Publikováno v: Oxidative Medicine and Cellular Longevity, Vol 2021 (2021)
Oxidative Medicine and Cellular Longevity
Vascular calcification (VC) describes the pathophysiological phenotype of calcium apatite deposition within the vascular wall, leading to vascular stiffening and the loss of compliance. VC is never benign; the presence and severity of VC correlate cl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42313a16d5684fea8e64c44a8151a33c
https://doaj.org/article/560126cbbb984cc389625474dc74c286
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5
Astaxanthin Counteracts Vascular Calcification In Vitro Through an Early Up-Regulation of SOD2 Based on a Transcriptomic Approach
Autor: You-Tien Tsai, Huei-Wen Chen, Jenq-Wen Huang, Hsiang-Yuan Yeh, Min-Tser Liao, Tzu-Hang Yuan, Chia-Ter Chao
Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 8530, p 8530 (2020)
Volume 21
Issue 22
Vascular calcification (VC) is a critical contributor to the rising cardiovascular risk among at-risk populations such as those with diabetes or renal failure. The pathogenesis of VC involves an uprising of oxidative stress, for which antioxidants ca
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f9adc24bb9751608523bb7d5036724b
https://pubmed.ncbi.nlm.nih.gov/33198315
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6
A combined microRNA and target protein-based panel for predicting the probability and severity of uraemic vascular calcification: a translational study
Autor: You-Tien Tsai, Chia-Ter Chao, Chih-Kang Chiang, Hsiang-Yuan Yeh, Huei-Wen Chen
Publikováno v: Cardiovasc Res
Aims Vascular calcification (VC) increases the future risk of cardiovascular events in uraemic patients, but effective therapies are still unavailable. Accurate identification of those at risk of developing VC using pathogenesis-based biomarkers is o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe05e09ee0e97f009b2f0339fec117df
https://pubmed.ncbi.nlm.nih.gov/33751037
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