Zobrazeno 1 - 10
of 18
pro vyhledávání: '"You-Soub Lee"'
Autor:
Ja-Yeol Lee, Jung-Won Lee, Tae-Geun Park, Sang-Hyun Han, Seo-Yeong Yoo, Kyoung-Mi Jung, Da-Mi Kim, Ok-Jun Lee, Dohun Kim, Xin-Zi Chi, Eung-Gook Kim, You-Soub Lee, Suk-Chul Bae
Publikováno v:
Cells, Vol 12, Iss 20, p 2438 (2023)
Oncogenic K-RAS mutations occur in approximately 25% of human lung cancers and are most frequently found in codon 12 (G12C, G12V, and G12D). Mutated K-RAS inhibitors have shown beneficial results in many patients; however, the inhibitors specifically
Externí odkaz:
https://doaj.org/article/df8bb4e41999448592430ef0055d38bb
Publikováno v:
Cells, Vol 12, Iss 5, p 708 (2023)
A cell cycle is a series of events that takes place in a cell as it grows and divides. At the G1 phase of cell cycle, cells monitor their cumulative exposure to specific signals and make the critical decision to pass through the restriction (R)-point
Externí odkaz:
https://doaj.org/article/dd1719ce589445a88288d836a578d16d
Autor:
Jung-Won Lee, Da-Mi Kim, Ju-Won Jang, Tae-Geun Park, Soo-Hyun Song, You-Soub Lee, Xin-Zi Chi, Il Yeong Park, Jin-Won Hyun, Yoshiaki Ito, Suk-Chul Bae
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
The transcription factor RUNX3 plays a key role in the restriction point of cell cycle. Here the authors showed that RUNX3 binds and opens chromatin structure of restriction point associated genes, by sequential recruitment of chromatin remodeling co
Externí odkaz:
https://doaj.org/article/ce5cd98dd35b4a8b97f2416472079307
Publikováno v:
Cell Proliferation
Objectives Runx3, a member of the Runx family of transcription factors, has been studied as a tumour suppressor and key player of organ development. In a previous study, we reported differentiation failure and excessive angiogenesis in the liver of R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41bca3190c9b49215194830f88960c3e
https://doi.org/10.1111/cpr.13138
https://doi.org/10.1111/cpr.13138
Autor:
Da-Mi Kim, Ju-Won Jang, You-Soub Lee, Soo-Hyun Song, Suk-Chul Bae, Jung-Won Lee, Jin-Won Hyun, Yoshiaki Ito, Xin-Zi Chi, Tae-Geun Park, Il Yeong Park
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Nature Communications
Nature Communications
The cellular decision regarding whether to undergo proliferation or death is made at the restriction (R)-point, which is disrupted in nearly all tumors. The identity of the molecular mechanisms that govern the R-point decision is one of the fundament
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4462c90fa469e982ae8dd326d0d277f
https://doaj.org/article/ce5cd98dd35b4a8b97f2416472079307
https://doaj.org/article/ce5cd98dd35b4a8b97f2416472079307
Autor:
Il Yeong Park, Ju-Won Jang, Tae-Geun Park, Da-Mi Kim, Jung-Won Lee, Suk-Chul Bae, Jin-Won Hyun, Xin-Zi Chi, You-Soub Lee, Yoshiaki Ito
The cellular decision regarding whether to undergo proliferation or death is made at the restriction (R)-point, which is disrupted in nearly all tumors. The identity of the molecular mechanisms that govern the R-point decision is one of the fundament
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5742c55aa461158a0c706a93b9bda98
https://doi.org/10.1101/409227
https://doi.org/10.1101/409227
Autor:
Ju-Won Jang, Jung-Won Lee, Jang-Hyun Kim, Linda Shyue Huey Chuang, Eung-Gook Kim, Jin-Haeng Chung, Byeung-Sub Choi, Ok-Jun Lee, Ying-Hui Li, Suk-Chul Bae, Da-Mi Kim, Joo-Won Suh, You Mie Lee, Xin-Zi Chi, Yoshiaki Ito, You-Soub Lee, Min-Kyu Kim
Publikováno v:
Cancer Cell. 24:603-616
Summary Targeted inactivation of Runx3 in mouse lung induced mucinous and nonmucinous adenomas and markedly shortened latency of adenocarcinoma formation induced by oncogenic K-Ras. RUNX3 was frequently inactivated in K-RAS mutated human lung adenoca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7385f58372407bfd9d526ed7822afb87
https://doi.org/10.1016/j.ccr.2013.10.003
https://doi.org/10.1016/j.ccr.2013.10.003
Autor:
Halagowder Devaraj, Byung-Chul Oh, Suk-Chul Bae, Yun-Mi Goh, Ok-Jun Lee, Senthilkumar Cinghu, You-Soub Lee
Publikováno v:
Journal of Cellular Physiology. 227:1071-1080
As H. pylori infection progresses, intestinal metaplasia (IM), a key event in gastric carcinogenesis, develops in the stomach. The mechanism by which H. pylori infection causes the trans-differentiation of gastric cells to intestinal-type cells remai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e88f9dfc49f833e07404ebecbeb7e9c6
https://doi.org/10.1002/jcp.22820
https://doi.org/10.1002/jcp.22820
Autor:
Young-Won Yun, So-Young Ji, Ki-Wan Oh, Kyeong-Mi Choi, Youn-Sun Lee, So Yong Lee, Jin-Tae Hong, You-Soub Lee, Hwan-Soo Yoo, Dong-Mi Sin, Mi-Hwa Choi
Publikováno v:
Cell Proliferation. 44:320-329
Objectives: Melanoma is the most aggressive form of skin cancer, and it resists chemotherapy. Candidate drugs for effective anti-cancer treatment have been sought from natural resources. Here, we have investigated anti-proliferative activity of myrio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5e71853ec921484554bde7145290a08
https://doi.org/10.1111/j.1365-2184.2011.00761.x
https://doi.org/10.1111/j.1365-2184.2011.00761.x
Autor:
Jong Min Lee, You Soub Lee, Sung Won Cho, Hyun-Mo Ryoo, Akihiro Hosoya, Han Sung Jung, Kyoung Won Cho, Suk Chul Bae, Jeong Oh Shin
Publikováno v:
Differentiation. 81:261-268
The runt-domain transcription factor Runx3 plays crucial roles during development such as regulating gene expression. It has been shown that Runx3 is involved in neurogenesis, thymopoiesis and functions like a tumor suppressor. Runx3 null mouse die s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ec41bec5c709883acfd0b1e0ca1cf9e
https://doi.org/10.1016/j.diff.2011.02.001
https://doi.org/10.1016/j.diff.2011.02.001