Zobrazeno 1 - 10
of 15
pro vyhledávání: '"You Zhe Lin"'
Autor:
You-Zhe Lin, Shu-Hsuan Liu, Wan-Rong Wu, Yi-Chun Shen, Yuan-Liang Wang, Chien-Ching Liao, Pei-Le Lin, Han Chang, Liang-Chih Liu, Wei-Chung Cheng, Shao-Chun Wang
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 241-251 (2022)
Programmed cell death protein 1 (PD-1)/ programmed cell death protein ligand 1 (PD-L1) is the key immune checkpoint governing evasion of advanced cancer from immune surveillance. Immuno-oncology (IO) therapy targeting PD-1/PD-L1 with traditional anti
Externí odkaz:
https://doaj.org/article/423d23f17e274b99b22b9109a1cabf8b
Autor:
Yuan-Liang Wang, Chuan-Chun Lee, Yi-Chun Shen, Pei-Le Lin, Wan-Rong Wu, You-Zhe Lin, Wei-Chung Cheng, Han Chang, Yu Hung, Yi-Chun Cho, Liang-Chih Liu, Wei-Ya Xia, Jin-Huei Ji, Ji-An Liang, Shu-Fen Chiang, Chang-Gong Liu, Jun Yao, Mien-Chie Hung, Shao-Chun Wang
Publikováno v:
Cell Reports, Vol 36, Iss 8, Pp 109537- (2021)
Summary: Increased DNA replication and metastasis are hallmarks of cancer progression, while deregulated proliferation often triggers sustained replication stresses in cancer cells. How cancer cells overcome the growth stress and proceed to metastasi
Externí odkaz:
https://doaj.org/article/5a0b5d40f77148d2b98ba7f8fdd61fc7
Autor:
You-Zhe, Lin, Chuan-Chun, Lee, Der-Yang, Cho, Yuan-Liang, Wang, Chia-Yun, Chen, Ching-Yu, Weng, Shao-Chih, Chiu, Mien-Chie, Hung, Shao-Chun, Wang
Publikováno v:
Am J Cancer Res
Anti-estrogens as hormone therapy are the mainstay treatment for estrogen receptor (ER)-positive breast cancer. ER inhibitors through modulating the transcriptional function of ER have been the frontline anti-estrogens to which refractory phenotype o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::55cbefa050365f7bb5c71ce05a005af5
https://europepmc.org/articles/PMC8493389/
https://europepmc.org/articles/PMC8493389/
Publikováno v:
Biochemical and Biophysical Research Communications. 510:42-47
Epidermal growth factor receptor (EGFR) plays a significant role in promoting breast cancer progression. However, targeting EGFR as a single treatment only resulted in moderate efficacy to the disease. The underlying mechanism of low responsiveness t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc7c226a9f7cbab892e4cb0a63b6c29e
https://doi.org/10.1016/j.bbrc.2018.12.187
https://doi.org/10.1016/j.bbrc.2018.12.187
Autor:
Wan Rong Wu, You Zhe Lin, Chen Yuan Lin, Shao Chun Wang, Yi Chun Shen, Yuan-Liang Wang, Mien Chie Hung, Wei Jan Wang
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 13
International Journal of Molecular Sciences, Vol 22, Iss 6938, p 6938 (2021)
Volume 22
Issue 13
International Journal of Molecular Sciences, Vol 22, Iss 6938, p 6938 (2021)
A group of clinically approved cancer therapeutic tyrosine kinase inhibitors was screened to test their effects on the expression of angiotensin-converting enzyme 2 (ACE2), the cell surface receptor for SARS-CoV-2. Here, we show that the receptor tyr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b618bbbb9533a71e3d82bb58ef0b046c
Autor:
Yuan-Liang Wang, Wan-Rong Wu, Pei-Le Lin, Yi-Chun Shen, You-Zhe Lin, Hong-Wei Li, Kai-Wen Hsu, Shao-Chun Wang
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 10; Pages: 5679
Invasion is the most prominent lethal feature of malignant cancer. However, how cell proliferation, another important feature of tumor development, is integrated with tumor invasion and the subsequent cell dissemination from primary tumors is not wel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ace5c218d51678080bce83ba8f89ede
https://doi.org/10.3390/ijms23105679
https://doi.org/10.3390/ijms23105679
Autor:
Chuan Chun Lee, Han Chang, Yuan-Liang Wang, Wan Rong Wu, Liang Chih Liu, Chang Gong Liu, Pei Le Lin, Shu-Fen Chiang, Mien Chie Hung, Yi Chun Shen, Yu Hung, Shao Chun Wang, Yi Chun Cho, You Zhe Lin, Jun Yao, Wei Ya Xia, Ji An Liang, Wei-Chung Cheng, Jin Huei Ji
Publikováno v:
Cell Reports, Vol 36, Iss 8, Pp 109537-(2021)
Summary: Increased DNA replication and metastasis are hallmarks of cancer progression, while deregulated proliferation often triggers sustained replication stresses in cancer cells. How cancer cells overcome the growth stress and proceed to metastasi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eaf25370a7afbc0db8ff469dfeb9d4b
https://pubmed.ncbi.nlm.nih.gov/34433039
https://pubmed.ncbi.nlm.nih.gov/34433039
Autor:
Liang Chih Liu, Yu Hung, Chih Jung Chen, Yuan-Liang Wang, Shao Chun Wang, Wan Rong Wu, You Zhe Lin
Publikováno v:
Breast (Edinburgh, Scotland). 46
Cancer cells are known to produce and secret extracellular vesicles for intercellular communication through the carried cargos. HOTAIR (HOX transcript antisense intergenic RNA), a well-studied long non-coding RNA (lncRNA), plays a critical role in ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87b1ce7d946ff0d0329faa90f7f17dcb
https://pubmed.ncbi.nlm.nih.gov/31100572
https://pubmed.ncbi.nlm.nih.gov/31100572
Autor:
Hui-Ting Hsu, You-Zhe Lin, Tzer-Min Kuo, Shun-Yuan Luo, Kun-Tu Yeh, Ying-Chin Ko, Srinivasan Nithiyanantham, Chi-Pin Lee
Publikováno v:
Journal of cellular physiology. 234(8)
Areca nut has been evaluated as a group I carcinogen to humans. However, the exact compounds of areca nut causing oral cancer remain unproven. Previous findings from our lab revealed that arecoline N-oxide (ANO), a metabolite of arecoline, exhibits a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fce66157c0e574cb1413e1f3ba0117ed
https://pubmed.ncbi.nlm.nih.gov/30624777
https://pubmed.ncbi.nlm.nih.gov/30624777
Autor:
Yuan-Chien Chen, Tzer-Min Kuo, You-Zhe Lin, Ying-Chin Ko, Pei-Ying Chang, Po-Ku Chen, Chun Hung Hua
Publikováno v:
Journal of agricultural and food chemistry. 65(47)
Areca nut is strongly associated with oral squamous cell carcinoma (OSCC) occurrence. Arecoline N-oxide (ANO), a metabolite of the areca alkaloid arecoline, exhibits an oral fibrotic effect in NOD/SCID mice. Caspase-8, a cysteine protease encoded by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08c1e852ee96b4b04ac94834eacb9a6e
https://pubmed.ncbi.nlm.nih.gov/29092399
https://pubmed.ncbi.nlm.nih.gov/29092399