Zobrazeno 1 - 10
of 49
pro vyhledávání: '"You Qing Cai"'
Autor:
Zhe Yu, Qi Fang, Xian Xiao, Yi-Zhi Wang, You-Qing Cai, Hui Cao, Gang Hu, Zhong Chen, Jian Fei, Neng Gong, Tian-Le Xu
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69883 (2013)
The mechanism underlying the pathogenesis of schizophrenia remains poorly understood. The hyper-dopamine and hypo-NMDA receptor hypotheses have been the most enduring ideas. Recently, emerging evidence implicates alterations of the major inhibitory s
Externí odkaz:
https://doaj.org/article/cd322431d8c14263808c8d711dfffa15
Publikováno v:
Neuroscience
Increasing evidence suggests that long-term opioids and pain induce similar adaptive changes in the brain’s reward circuits, however, how pain alters the addictive properties of opioids remains poorly understood. In this study using a rat model of
Recent years have seen a surging number of epigenetic studies and rapid progress in understanding of epigenetic mechanisms of gene regulation and their dysfunctions in the pathogenesis of neurological diseases such as chronic pain. As we gain increas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a315030d984c6e0cd492b3c1d9915a40
https://doi.org/10.1016/b978-0-12-814070-3.00006-5
https://doi.org/10.1016/b978-0-12-814070-3.00006-5
Autor:
You-Qing Cai1 youcai@mdanderson.org, Wei Wang1 wwangjn@gmail.com, Yuan-Yuan Hou1 YHou@mdanderson.org, Zhizhong Z Pan1 zzpan@mdanderson.org
Publikováno v:
Molecular Pain. 2014, Vol. 10 Issue 1, p1-20. 20p. 1 Color Photograph, 5 Graphs.
Publikováno v:
Molecular Pain
The amygdala is important in regulation of emotion-associated behavioral responses both to positive reinforcing stimuli such as addicting opioids and to negative aversive stimuli such as fear and pain. Glutamatergic neurotransmission in amygdala play
Autor:
Mohamed M. Kamal, Zhizhong Z. Pan, Bethany Veo, Joy Gumin, Mark E. Maynard, Dina H. Kassem, Anantha Marisetty, You Qing Cai, Matthew D. Cykowski, Pramod K. Dash, Gregory N. Fuller, Li Lu, Connie C. Weng, Kimberly N. Hood, Bin Liu, Sadhan Majumder
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Overexpression of REST has been implicated in brain tumors, ischemic insults, epilepsy, and movement disorders such as Huntington’s disease. However, owing to the lack of a conditional REST overexpression animal model, the mechanism of action of RE
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 38(28)
The amygdala is important for processing emotion, including negative emotion such as anxiety and depression induced by chronic pain. Although remarkable progress has been achieved in recent years on amygdala regulation of both negative (fear) and pos
Publikováno v:
Acta Biochimica et Biophysica Sinica. 45:578-585
Attention deficit/hyperactivity disorder (ADHD) is characterized by hyperactivity, impaired sustained attention, impulsivity, and is usually accompanied by varying degrees of learning difficulties and lack of motor coordination. However, the pathophy
Publikováno v:
The Journal of Neuroscience. 33:1577-1588
GluA1 subunits of AMPA glutamate receptors are implicated in the synaptic plasticity induced by drugs of abuse for behaviors of drug addiction, but GluA1 roles in emotional learning and memories of drug reward in the development of drug addiction rem
Publikováno v:
Neuropsychopharmacology. 37:2780-2788
The rewarding properties of opioids are essential driving force for compulsive drug-seeking and drug-taking behaviors in the development of opioid-mediated drug addiction. Prior drug use enhances sensitivity to the rewarding effects of subsequently u