Zobrazeno 1 - 10
of 32
pro vyhledávání: '"You Na Kang"'
Autor:
Jim Delproposto, Michael K. Gilson, Ginger Kubish, Stephen K. Burley, Symon Gathiaka, Michael Chiu, Jeanne A. Stuckey, W. Patrick Walters, Rommie E. Amaro, Victoria A. Feher, James B. Dunbar, You Na Kang, Shuai Liu, Heather A. Carlson, Huanwang Yang
Publikováno v:
Journal of computer-aided molecular design. 30(9)
The Drug Design Data Resource (D3R) ran Grand Challenge 2015 between September 2015 and February 2016. Two targets served as the framework to test community docking and scoring methods: (i) HSP90, donated by AbbVie and the Community Structure Activit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60a756366c63733a2351f46d733e770b
https://pubmed.ncbi.nlm.nih.gov/27696240
https://pubmed.ncbi.nlm.nih.gov/27696240
Publikováno v:
Crystal Growth & Design. 11:1294-1298
Obtaining single crystals for X-ray diffraction remains a major bottleneck in structural biology; when existing crystal growth methods fail to yield suitable crystals, often the target rather than the crystallization approach is reconsidered. Here we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd97e5f2173c3142e29eaf6294de1f70
https://doi.org/10.1021/cg101518f
https://doi.org/10.1021/cg101518f
Autor:
Paula W. Allan, Steven E. Ealick, You Na Kang, Jing Wen Ting, Yang Zhang, William B. Parker, Chi Yao Chang
Publikováno v:
Acta Crystallographica Section D Biological Crystallography. 66:155-162
Purine nucleoside phosphorylase (PNP) catalyzes the reversible phosphorolysis of purine ribonucleosides to the corresponding free bases and ribose 1-phosphate. The crystal structure of grouper iridovirus PNP (givPNP), corresponding to the first PNP g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2881063e3983d5e6611b89191c41de87
https://doi.org/10.1107/s0907444909048276
https://doi.org/10.1107/s0907444909048276
Publikováno v:
Biochemistry. 46:5050-5062
Inosine 5'-monophosphate (IMP) cyclohydrolase catalyzes the cyclization of 5-formaminoimidazole-4-carboxamide ribonucleotide (FAICAR) to IMP in the final step of de novo purine biosynthesis. Two major types of this enzyme have been discovered to date
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9acf9024a662168a2280c1c59531274
https://doi.org/10.1021/bi061637j
https://doi.org/10.1021/bi061637j
Publikováno v:
Biochemistry. 45:14609-14620
Pyridoxal 5'-phosphate (PLP) is the biologically active form of vitamin B6 and is an important cofactor for several of the enzymes involved in the metabolism of amine-containing natural products such as amino acids and amino sugars. The PLP synthase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9566f13ff5de42b2a28381caba76756f
https://doi.org/10.1021/bi061464y
https://doi.org/10.1021/bi061464y
Publikováno v:
Biochemistry. 44:5106-5116
Two different conformations of the inner loop (residues 340-346) have been found in the soybean beta-amylase structures. In the "product form", the Thr 342 residue creates hydrogen bonds with Glu 186 (catalytic acid) and with the glucose residues at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b101f9247552c94f690e6b045cff604e
https://doi.org/10.1021/bi0476580
https://doi.org/10.1021/bi0476580
Publikováno v:
Journal of Molecular Biology. 339:1129-1140
It has previously been suggested that the glutamic acid residues Glu186 and Glu380 of soybean beta-amylase play critical roles as a general acid and a general base catalyst, respectively. In order to confirm the roles of Glu186 and Glu380, each resid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ae04e3e2a1083fba02507f5bcd36c96
https://doi.org/10.1016/j.jmb.2004.04.029
https://doi.org/10.1016/j.jmb.2004.04.029
Publikováno v:
Acta Crystallographica Section A Foundations and Advances. 72:s40-s41
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1d681857edc622d1849c9f02133321f
https://doi.org/10.1107/s205327331609937x
https://doi.org/10.1107/s205327331609937x
Autor:
Jeanne A. Stuckey, Emilio Xavier Esposito, Ginger Kubish, You Na Kang, James Delproposto, Aqeel Ahmed, Krishnapriya Chinnaswamy, Heather A. Carlson, Kelly L. Damm-Ganamet, James B. Dunbar, Richard D. Smith, Jason E. Gestwicki
Publikováno v:
Journal of Chemical Information and Modeling
A major goal in drug design is the improvement of computational methods for docking and scoring. The Community Structure Activity Resource (CSAR) has collected several data sets from industry and added in-house data sets that may be used for this pur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23599878faedbb311c3405a414d8695e
https://pubmed.ncbi.nlm.nih.gov/23617227
https://pubmed.ncbi.nlm.nih.gov/23617227
Publikováno v:
Acta crystallographica. Section D, Biological crystallography. 67(Pt 9)
The crystallization and structural characterization of bovine liver catalase (BLC) has been intensively studied for decades. Forms I and II of BLC have previously been fully characterized using single-crystal X-ray diffraction. Form III has previousl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::820e592e76048197449370b9c73605a1
https://pubmed.ncbi.nlm.nih.gov/21904028
https://pubmed.ncbi.nlm.nih.gov/21904028