Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Yosuke Shimaki"'
Autor:
Tony S Cardno, Yosuke Shimaki, Brad E Sleebs, Kurt Lackovic, John P Parisot, Rebecca M Moss, Caillan Crowe-McAuliffe, Suneeth F Mathew, Christina D Edgar, Torsten Kleffmann, Warren P Tate
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0139036 (2015)
Frameshifting during translation of viral or in rare cases cellular mRNA results in the synthesis of proteins from two overlapping reading frames within the same mRNA. In HIV-1 the protease, reverse transcriptase, and integrase enzymes are in a secon
Externí odkaz:
https://doaj.org/article/20a5de53f7ec45b591411810ac7d69b1
Autor:
Gregory M. Cook, Lars J. C. Jeuken, Stephen P. Muench, Keith Ireton, Yoshio Nakatani, Debajyoti Dutta, Yosuke Shimaki
Publikováno v:
Journal of the American Chemical Society. 142(3)
Type II NADH:quinone oxidoreductase (NDH-2) plays a crucial role in the respiratory chains of many organisms. Its absence in mammalian cells makes NDH-2 an attractive new target for developing antimicrobials and antiprotozoal agents. We established a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e51cb0741f6ed01b0185ae72b78f191
https://pubmed.ncbi.nlm.nih.gov/31880924
https://pubmed.ncbi.nlm.nih.gov/31880924
Autor:
David Aragão, Hannah R. Bridges, Yosuke Shimaki, Gregory M. Cook, Emily J. Parker, Wanting Jiao, Yoshio Nakatani, Jessica Petri, Euan R. Russell
Publikováno v:
Biochimica et Biophysica Acta
Type II NADH:quinone oxidoreductase (NDH-2) is a proposed drug-target of major pathogenic microorganisms such as Mycobacterium tuberculosis and Plasmodium falciparum. Many NDH-2 inhibitors have been identified, but rational drug development is impede
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83df88655d28f92e8c752ef8e1b3f443
https://doi.org/10.1016/j.bbabio.2018.03.014
https://doi.org/10.1016/j.bbabio.2018.03.014
Autor:
Yosuke Shimaki, Gregory M. Cook, David Aragão, Wanting Jiao, Jessica Petri, Yoshio Nakatani, Emily J. Parker
Publikováno v:
Acta crystallographica. Section F, Structural biology communications. 73(Pt 10)
Type II NADH:quinone oxidoreductase (NDH-2) is a respiratory enzyme found in the electron-transport chain of many species, with the exception of mammals. It is a 40–70 kDa single-subunit monotopic membrane protein that catalyses the oxidation of NA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd987ca207e936eb7c9b6526be9b08d3
https://pubmed.ncbi.nlm.nih.gov/28994401
https://pubmed.ncbi.nlm.nih.gov/28994401
Autor:
Warren P. Tate, John P Parisot, Rebecca M Moss, Suneeth F. Mathew, Torsten Kleffmann, Tony S. Cardno, Brad E. Sleebs, Yosuke Shimaki, Caillan Crowe-McAuliffe, Kurt Lackovic, Christina D. Edgar
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 10, p e0139036 (2015)
PLoS ONE, Vol 10, Iss 10, p e0139036 (2015)
Frameshifting during translation of viral or in rare cases cellular mRNA results in the synthesis of proteins from two overlapping reading frames within the same mRNA. In HIV-1 the protease, reverse transcriptase, and integrase enzymes are in a secon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1307c68b2ad27c614da560754eed9eb
https://pubmed.ncbi.nlm.nih.gov/26447468
https://pubmed.ncbi.nlm.nih.gov/26447468