Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Yosuke Ochiai"'
Autor:
Hiroyuki Ozawa, Takahiro Yoshihama, Shogo Gishitomi, Natsuki Watanabe, Kotaro Ichikawa, Keiichi Sato, Kenta Watanabe, Katsuhiko Takano, Yosuke Ochiai, Hiroki Yamanaka, Atsushi Maruyama
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract DNA analysis of large herbivore feces samples collected from seagrass beds at two distant sites (Irabu Island in Miyako Islands and Kushi in Okinawa Island) in the Ryukyu Islands proved that some of these feces were from dugongs, which had b
Externí odkaz:
https://doaj.org/article/b058748b766c487b914d9e8d4ed6fa53
Autor:
Zhengyu Jiang, Quin T. Waterbury, Ermanno Malagola, Na Fu, Woosook Kim, Yosuke Ochiai, Feijing Wu, Chandan Guha, Carrie J. Shawber, Kelley S. Yan, Timothy C. Wang
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 17, Iss 3, Pp 321-346 (2024)
Background & Aims: The intestinal epithelium functions both in nutrient absorption and as a barrier, separating the luminal contents from a network of vascular, fibroblastic, and immune cells underneath. After injury to the intestine, multiple cell p
Externí odkaz:
https://doaj.org/article/55559053220146c28119bfea1537115d
Autor:
Feijing Wu, Zhengyu Jiang, Jin Qian, Hiroki Kobayashi, Quin T. Waterbury, Ruth A. White, Yosuke Ochiai, Xiaofei Zhi, Ruhong Tu, Biyun Zheng, Qiongyu Shi, Leah B. Zamechek, Timothy C. Wang
Publikováno v:
STAR Protocols, Vol 5, Iss 1, Pp 102836- (2024)
Summary: Here, we present a protocol for rapidly isolating single cells from the mouse pancreas, minimizing damage caused by digestive enzymes in exocrine cells. We guide you through steps to optimize the dissection sequence, enzyme composition, and
Externí odkaz:
https://doaj.org/article/c3193e334731495c8e251f2e78edfb50
Autor:
Na Fu, Feijing Wu, Zhengyu Jiang, Woosook Kim, Tuo Ruan, Ermanno Malagola, Yosuke Ochiai, Osmel Companioni Nápoles, Giovanni Valenti, Ruth A. White, Bryana R. Belin, Leah B. Zamechek, Jonathan S. LaBella, Timothy C. Wang
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 4, Pp 1119-1138 (2021)
Background & Aims: Histidine decarboxylase (HDC), the histamine-synthesizing enzyme, is expressed in a subset of myeloid cells but also marks quiescent myeloid-biased hematopoietic stem cells (MB-HSCs) that are activated upon myeloid demand injury. H
Externí odkaz:
https://doaj.org/article/3e92a611d5414af0b8d9dcf2161d2b1e
Autor:
Moritz Middelhoff, Giovanni Valenti, Lorenzo Tomassoni, Yosuke Ochiai, Bryana Belin, Ryota Takahashi, Ermanno Malagola, Henrik Nienhüser, Michael Finlayson, Yoku Hayakawa, Leah B. Zamechek, Bernhard W. Renz, C. Benedikt Westphalen, Michael Quante, Kara G. Margolis, Peter A. Sims, Pasquale Laise, Andrea Califano, Meenakshi Rao, Michael D. Gershon, Timothy C. Wang
Publikováno v:
Am J Physiol Gastrointest Liver Physiol
Intestinal ganglionic cells in the adult enteric nervous system (ENS) are continually exposed to stimuli from the surrounding microenvironment and need at times to respond to disturbed homeostasis following acute intestinal injury. The kinase DCLK1 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21a7d594d4c31afe5510faa72449f84e
https://pubmed.ncbi.nlm.nih.gov/35319286
https://pubmed.ncbi.nlm.nih.gov/35319286
Autor:
Xiaofei Zhi, Feijing Wu, Jin Qian, Yosuke Ochiai, Guodong Lian, Ermanno Malagola, Timothy C. Wang
Publikováno v:
Cancer Research. 83:1193-1193
Tumor innervation contributes directly to cancer progression, but there appears to be organ-specific variation in the type of innervation. While our previous studies showed cholinergic signaling promoted gastric cancer and vagal denervation inhibited
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::911dde78f181b32e4258e6c9d770e066
https://doi.org/10.1158/1538-7445.am2023-1193
https://doi.org/10.1158/1538-7445.am2023-1193
Autor:
Yosuke Ochiai, Junpei Yamaguchi, Toshio Kokuryo, Tomoki Ebata, Masato Nagino, Yukihiro Yokoyama
Publikováno v:
Oncogene. 40:2273-2284
Recent findings suggest that the dissemination of tumor cells occurs at the early stage of breast and pancreatic carcinogenesis, which is known as early dissemination. The evidence of early dissemination has been demonstrated predominantly in the blo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e721755cf0e78558ff7f2a3894511e5
https://doi.org/10.1038/s41388-021-01706-8
https://doi.org/10.1038/s41388-021-01706-8
Autor:
Woosook Kim, Feijing Wu, Leah B. Zamechek, Timothy C. Wang, Ruth A. White, Jonathan S. LaBella, Osmel Companioni Nápoles, Bryana R. Belin, Zhengyu Jiang, Giovanni Valenti, Tuo Ruan, Yosuke Ochiai, Na Fu, Ermanno Malagola
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 4, Pp 1119-1138 (2021)
Background & Aims Histidine decarboxylase (HDC), the histamine-synthesizing enzyme, is expressed in a subset of myeloid cells but also marks quiescent myeloid-biased hematopoietic stem cells (MB-HSCs) that are activated upon myeloid demand injury. Ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::224142ad564e2fbb041f98a79e786ec3
http://www.sciencedirect.com/science/article/pii/S2352345X20301867
http://www.sciencedirect.com/science/article/pii/S2352345X20301867
Autor:
Masato Nagino, Yukihiro Yokoyama, Tomoki Ebata, Yosuke Ochiai, Junpei Yamaguchi, Toshio Kokuryo
Publikováno v:
Hepatology. 72:503-517
Background and aims Recent studies have suggested that trefoil factor family 1 (TFF1) functions as a tumor suppressor in gastric and pancreatic carcinogenesis. Approach and results To investigate the role of TFF1 in hepatocarcinogenesis, we performed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa93f950711535759997cc521a6177e8
https://doi.org/10.1002/hep.31039
https://doi.org/10.1002/hep.31039
Autor:
Ruth A. White, Quin T. Waterbury, Yosuke Ochiai, Leah B. Zamechek, Susan E. Bates, Timothy C. Wang
Publikováno v:
Cancer Research. 82:PR020-PR020
Immunotherapy, which can produce durable responses in some cancers, has generally proven ineffective in PDAC, partially due to an immunosuppressive tumor immune microenvironment (TIME). Adjunctive therapies to sensitize PDAC to immunotherapy have the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::010fadb812737253121fb49dc7057fe9
https://doi.org/10.1158/1538-7445.panca22-pr020
https://doi.org/10.1158/1538-7445.panca22-pr020