Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Yosuke Nagata"'
Autor:
Masaki Tsuchiya, Yuji Hara, Masaki Okuda, Karin Itoh, Ryotaro Nishioka, Akifumi Shiomi, Kohjiro Nagao, Masayuki Mori, Yasuo Mori, Junichi Ikenouchi, Ryo Suzuki, Motomu Tanaka, Tomohiko Ohwada, Junken Aoki, Motoi Kanagawa, Tatsushi Toda, Yosuke Nagata, Ryoichi Matsuda, Yasunori Takayama, Makoto Tominaga, Masato Umeda
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Myotube formation by fusion of myoblasts is essential for skeletal muscle formation, but which molecules regulate this process remains elusive. Here authors identify the mechanosensitive PIEZO1 channel as a key element, whose activity is regulated by
Externí odkaz:
https://doaj.org/article/a4b94536489a4c5abfb6db09652f9498
Autor:
Sosuke, Miyasato, Kurumi, Iwata, Reika, Mura, Shou, Nakamura, Keisuke, Yanagida, Hideo, Shindou, Yosuke, Nagata, Masahiro, Kawahara, Satoshi, Yamaguchi, Junken, Aoki, Asuka, Inoue, Teruyuki, Nagamune, Takao, Shimizu, Motonao, Nakamura
Publikováno v:
The FASEB Journal. 37
The G protein-coupled receptors, GPR43 (free fatty acid receptor 2, FFA2) and GPR41 (free fatty acid receptor 3, FFA3), are activated by short-chain fatty acids produced under various conditions, including microbial fermentation of carbohydrates. Pre
Autor:
Junken Aoki, Makoto Tominaga, Tomohiko Ohwada, Masaki Tsuchiya, Ryoichi Matsuda, Motomu Tanaka, Akifumi Shiomi, Yasunori Takayama, Tatsushi Toda, Karin Itoh, Ryo Suzuki, Ryotaro Nishioka, Masayuki X. Mori, Motoi Kanagawa, Yasuo Mori, Masaki Okuda, Yuji Hara, Kohjiro Nagao, Masato Umeda, Junichi Ikenouchi, Yosuke Nagata
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Nature Communications
Nature Communications
Myotube formation by fusion of myoblasts and subsequent elongation of the syncytia is essential for skeletal muscle formation. However, molecules that regulate myotube formation remain elusive. Here we identify PIEZO1, a mechanosensitive Ca2+ channel
Autor:
Namiko Kikkawa, Ryoichi Matsuda, Tomohisa Ohno, Masataka Shiozuka, Yosuke Nagata, Toshihiro Kogure
Publikováno v:
Cell Structure and Function. 34:77-88
Ectopic calcification occurs in the skeletal muscle of mdx mice, a dystrophin-deficient animal model of Duchenne muscular dystrophy. The purpose of this study was to clarify the mechanism of the calcification. The calcified deposits were identified a
Publikováno v:
The Journal of Cell Biology
Adult skeletal muscle is able to repeatedly regenerate because of the presence of satellite cells, a population of stem cells resident beneath the basal lamina that surrounds each myofiber. Little is known, however, of the signaling pathways involved
Autor:
Peter S. Zammit, Riyoichi Matsuda, Masato Umeda, Hideshi Kobayashi, Seiichiro Kawashima, Yosuke Nagata, Naoshi Ohta
Publikováno v:
Journal of Histochemistry & Cytochemistry. 54:375-384
Satellite cells are responsible for postnatal growth, hypertrophy, and regeneration of skeletal muscle. They are normally quiescent, and must be activated to fulfill these functions, yet little is known of how this is regulated. As a first step in de
Publikováno v:
Experimental cell research. 333(2)
Skeletal muscle stem cells named muscle satellite cells are normally quiescent but are activated in response to various stimuli, such as injury and overload. Activated satellite cells enter the cell cycle and proliferate to produce a large number of
Autor:
Ichizo Nishino, Yoriko Kojima, Masataka Shiozuka, Yosuke Nagata, Mizuko Yoshida, Tetsuo Higashi, Munehiro Date, Ikuya Nonaka, Ryoichi Matsuda, Kazuya Ohashi, Eiji Wada
Publikováno v:
The American journal of pathology. 184(11)
Duchenne muscular dystrophy is a lethal X-linked disease with no effective treatment. Progressive muscle degeneration, increased macrophage infiltration, and ectopic calcification are characteristic features of the mdx mouse, a murine model of Duchen
Autor:
Yosuke Nagata, Yuki Yuasa, Yoshiaki Nonomura, Eiji Wada, Masataka Shiozuka, Kazuya Ohashi, Ryoichi Matsuda
Publikováno v:
Experimental cell research. 326(1)
Skeletal muscle can regenerate repeatedly due to the presence of resident stem cells, called satellite cells. Because satellite cells are usually quiescent, they must be activated before participating in muscle regeneration in response to stimuli suc
Autor:
Yosuke Nagata, Jonathan R. Beauchamp, Frédéric Relaix, Terence A. Partridge, Peter S. Zammit, Ana Pérez Ruiz, Charlotte A. Collins
Publikováno v:
Journal of cell science. 119(Pt 9)
Skeletal muscle growth and regeneration are attributed to satellite cells - muscle stem cells resident beneath the basal lamina that surrounds each myofibre. Quiescent satellite cells express the transcription factor Pax7 and when activated, coexpres