Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Yosuke Ida"'
Autor:
Keisuke Endo, Tatsuya Sato, Araya Umetsu, Megumi Watanabe, Fumihito Hikage, Yosuke Ida, Hiroshi Ohguro, Masato Furuhashi
Publikováno v:
Heliyon, Vol 9, Iss 10, Pp e20713- (2023)
Adipose tissues are closely related to physiological functions and pathological conditions in most organs. Although differentiated 3T3-L1 preadipocytes have been used for in vitro adipose studies, the difference in cellular characteristics of adipoge
Externí odkaz:
https://doaj.org/article/ed1d2bccb0cc4b7ab1518e9c3b0e11ec
Autor:
Yuri Tsugeno, Masato Furuhashi, Tatsuya Sato, Megumi Watanabe, Araya Umetsu, Soma Suzuki, Yosuke Ida, Fumihito Hikage, Hiroshi Ohguro
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract The objective of the current study was to examine the effects of fibroblast growth factor-2 (FGF-2) on conjunctival fibrogenesis that was induced by the presence of transforming growth factor-β2 (TGF-β2). Two-dimension (2D) and three-dimen
Externí odkaz:
https://doaj.org/article/9e3ae7071bbb43888457f2eb19490c69
Autor:
Yosuke Ida, Araya Umetsu, Masato Furuhashi, Megumi Watanabe, Yuri Tsugeno, Soma Suzuki, Fumihito Hikage, Hiroshi Ohguro
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract The objective of the current study was to examine the roles of ROCK1 and 2 on the spatial architecture of human corneal stroma. We examined the effects of a pan-ROCK inhibitor (pan-ROCK-i), ripasudil, and a ROCK2 inhibitor (ROCK2-i), KD025 o
Externí odkaz:
https://doaj.org/article/bbbcf84cb01943108006513b6eb48188
Publikováno v:
FASEB BioAdvances, Vol 3, Iss 10, Pp 866-872 (2021)
Abstract To elucidate the pharmacological effects of Rho‐associated coiled‐coil containing protein kinase inhibitors (ROCK‐is), ripasudil (Rip), Y27632, and KD025, on human orbital fatty tissue, the human orbital fibroblasts (HOFs) were three
Externí odkaz:
https://doaj.org/article/80bb53e1f8194071bc5c8153d6f14b64
Autor:
Hiroyasu Katayama, Masato Furuhashi, Araya Umetsu, Fumihito Hikage, Megumi Watanabe, Hiroshi Ohguro, Yosuke Ida
Publikováno v:
Current Issues in Molecular Biology, Vol 43, Iss 3, Pp 1715-1725 (2021)
In the current study, to elucidate the pathological characteristics of myopic scleral stroma, three-dimensional (3D) cultures of human scleral stroma fibroblasts (HSSFs) with several axial lengths (AL, 22.80–30.63 mm) that were obtained from patien
Externí odkaz:
https://doaj.org/article/f6145c2df1914328bf91cb9ce6c40ab4
Publikováno v:
Biomedicines, Vol 11, Iss 9, p 2513 (2023)
To examine the epithelial–mesenchymal transition (EMT) that is induced on the human corneal stroma, two- and three-dimensional (2D and 3D) cultures of human corneal stroma fibroblasts (HCSFs) were used. In this study, HCSF 2D monolayers and 3D sphe
Externí odkaz:
https://doaj.org/article/fca08f0d2c934671b98e6b4dbf037163
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract To establish appropriate ex vivo models for a glaucomatous trabecular meshwork (TM), two-dimensional (2D) and three-dimensional (3D) cultures of human trabecular meshwork cells (HTM) were prepared in the presence of 250 nM dexamethasone (DEX
Externí odkaz:
https://doaj.org/article/a7ddc0f364e746eaaef259bff88b39bc
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract A pan-ROCK-inhibitor, ripasudil (Rip), and a ROCK2 inhibitor, KD025, were used To study the effects of Rho-associated coiled-coil containing protein kinase (ROCK)1 and 2 on two-dimensional (2D) and three-dimensional (3D) cultures of a TGFβ2
Externí odkaz:
https://doaj.org/article/da156467102a4b01aed4cc8bf8e6b77d
Autor:
Kaku Itoh, Masato Furuhashi, Yosuke Ida, Hiroshi Ohguro, Megumi Watanabe, Soma Suzuki, Fumihito Hikage
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract The fatty acid-binding protein4 (FABP4) and vascular endothelial growth factor A (VEGFA) play key roles in the metabolic and cardiovascular diseases, and proliferative diabetic retinopathy (PDR), respectively. To identify FABP4 in vitreous f
Externí odkaz:
https://doaj.org/article/26feea154246441f8f7b8d7fe773d6fd
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Previous our study reported that three-dimension (3D) cultures of human orbital fibroblasts (HOFs) replicated the etiology of deepening of the upper eyelid sulcus (DUES) caused by prostaglandin F2α analogues (PGF2α-ags). To examine this fu
Externí odkaz:
https://doaj.org/article/74b29f2fbaac40889ecda51ca5b4a797