Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Yosuke, Toyoda"'
Autor:
Yosuke Toyoda, Angqi Zhu, Fang Kong, Sisi Shan, Jiawei Zhao, Nan Wang, Xiaoou Sun, Linqi Zhang, Chuangye Yan, Brian K. Kobilka, Xiangyu Liu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract The α1A-adrenergic receptor (α1AAR) belongs to the family of G protein-coupled receptors that respond to adrenaline and noradrenaline. α1AAR is involved in smooth muscle contraction and cognitive function. Here, we present three cryo-elec
Externí odkaz:
https://doaj.org/article/50bdf748659847fea35e92cceaacec7d
Publikováno v:
International Journal of Offshore and Polar Engineering. 29:467-473
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f144d45a61b1e7df7ba1fb5a5766ae28
https://doi.org/10.17736/ijope.2019.jc756
https://doi.org/10.17736/ijope.2019.jc756
Publikováno v:
Volume 8: CFD and FSI.
In this study, a numerical prediction model for vortex-induced motions (VIM) of 4-circular-column floater was developed from a database of hydrodynamic forces acquired from the forced oscillation tests. A set of combinations of oscillation frequencie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e92375480e5cb54f610774a55e9b356d
https://doi.org/10.1115/omae2020-18511
https://doi.org/10.1115/omae2020-18511
Publikováno v:
Journal of Japan Society of Civil Engineers, Ser. B2 (Coastal Engineering). 78:I_613-I_618
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8330db0964db3c8501993e4523c2fd82
https://doi.org/10.2208/kaigan.78.2_i_613
https://doi.org/10.2208/kaigan.78.2_i_613
Autor:
Dean Thumkeo, Ryota Shinohara, Keisuke Watanabe, Hirohide Takebayashi, Yosuke Toyoda, Kiyoshi Tohyama, Toshimasa Ishizaki, Tomoyuki Furuyashiki, Shuh Narumiya
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25465 (2011)
During development of the central nervous system, the apical-basal polarity of neuroepithelial cells is critical for homeostasis of proliferation and differentiation of neural stem cells. While adherens junctions at the apical surface of neuroepithel
Externí odkaz:
https://doaj.org/article/3c4d3feca4644eef8d6fb89968ac5bfa
Autor:
Yosuke, Toyoda, Kazushi, Morimoto, Ryoji, Suno, Shoichiro, Horita, Keitaro, Yamashita, Kunio, Hirata, Yusuke, Sekiguchi, Satoshi, Yasuda, Mitsunori, Shiroishi, Tomoko, Shimizu, Yuji, Urushibata, Yuta, Kajiwara, Tomoaki, Inazumi, Yunhon, Hotta, Hidetsugu, Asada, Takanori, Nakane, Yuki, Shiimura, Tomoya, Nakagita, Kyoshiro, Tsuge, Suguru, Yoshida, Tomoko, Kuribara, Takamitsu, Hosoya, Yukihiko, Sugimoto, Norimichi, Nomura, Miwa, Sato, Takatsugu, Hirokawa, Masahiro, Kinoshita, Takeshi, Murata, Kiyoshi, Takayama, Masaki, Yamamoto, Shuh, Narumiya, So, Iwata, Takuya, Kobayashi
Publikováno v:
Nature chemical biology. 15(1)
Prostaglandin E receptor EP4, a G-protein-coupled receptor, is involved in disorders such as cancer and autoimmune disease. Here, we report the crystal structure of human EP4 in complex with its antagonist ONO-AE3-208 and an inhibitory antibody at 3.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::825706acd6d2b9c5a166a78a9dfdb612
https://pubmed.ncbi.nlm.nih.gov/30510193
https://pubmed.ncbi.nlm.nih.gov/30510193
Autor:
Yosuke Toyoda, Mamoru Koketsu
Publikováno v:
Tetrahedron. 68:10496-10501
Selenium-containing heterocycles have been interested because of their unique reactivity and potential biological activity. Recently, several selenium-containing heterocycles bearing an exocyclic imine have been synthesized by isoselenocyanates. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a3b4aa18ab51347836a5f69040c7c70
https://doi.org/10.1016/j.tet.2012.07.083
https://doi.org/10.1016/j.tet.2012.07.083
Autor:
Satoshi Yasuda, Yuta Kajiwara, Takuya Kobayashi, Kazushi Morimoto, Masahiro Kinoshita, So Iwata, Takeshi Murata, Yosuke Toyoda, Ryoji Suno
Publikováno v:
ResearcherID
G protein-coupled receptors (GPCRs), which are indispensable to life and also implicated in a number of diseases, construct important drug targets. For the efficient structure-guided drug design, however, their structural stabilities must be enhanced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48dd652fbda90359c50e509a66c8cb97
https://doi.org/10.1016/j.bpj.2017.11.1309
https://doi.org/10.1016/j.bpj.2017.11.1309
Autor:
Hiroko Kubo, Yosuke Toyoda, Toshifumi Dohi, Tomofumi Nakae, Yasuyuki Kita, Daichi Koseki, Tohru Kamitanaka
Publikováno v:
ChemInform. 46
The highly reactive hypervalent iodine dimer [Ph(CF3COO)I]-O-[I(OCOCF3)Ph] is shown to promote the oxidative phenolic coupling with styrenes to afford different benzofuran derivatives.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2be8b9460a0b57dc90ecf42928c1d4d4
https://doi.org/10.1002/chin.201520040
https://doi.org/10.1002/chin.201520040