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Akademický článek

First-in-man histotripsy of hepatic tumors: the THERESA trial, a feasibility study

Autor: Joan Vidal-Jove, Xavier Serres, Eli Vlaisavljevich, Jon Cannata, Alex Duryea, Ryan Miller, Xavier Merino, Manuela Velat, Yossi Kam, Ryan Bolduan, Joseph Amaral, Timothy Hall, Zhen Xu, Fred T. Lee, Timothy J. Ziemlewicz

Publikováno v: International Journal of Hyperthermia, Vol 39, Iss 1, Pp 1115-1123 (2022)

Rationale Current hepatic locoregional therapies are limited in terms of effectiveness and toxicities. Given promising pre-clinical results, a first in-human trial was designed to assess the technical effectiveness and safety profile of histotripsy,

Externí odkaz: https://doaj.org/article/ce91c8ab6b4244dcb1db9a25e36031da

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Synthesis and characterization of near IR fluorescent albumin nanoparticles for optical detection of colon cancer

Autor: Enav Corem-Salkmon, Shlomo Margel, Igor Grinberg, Sarit Cohen, Yossi Kam, Michal Pellach, Abraham Rubinstein

Publikováno v: Materials Science and Engineering: C. 33:923-931

Near IR (NIR) fluorescent human serum albumin (HSA) nanoparticles hold great promise as contrast agents for tumor diagnosis. HSA nanoparticles are considered to be biocompatible, non-toxic and non-immunogenic. In addition, NIR fluorescence properties

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58095dd90c4e9c082d21dcda0faa1061
https://doi.org/10.1016/j.msec.2012.11.022

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Detection of Endogenous K-ras mRNA in Living Cells at a Single Base Resolution by a PNA Molecular Beacon

Autor: Aviram Nissan, Eylon Yavin, David Halle, Abraham Rubinstein, Yossi Kam

Publikováno v: Molecular Pharmaceutics. 9:685-693

Detection of mRNA alterations is a promising approach for identifying biomarkers as means of differentiating benign from malignant lesions. By choosing the KRAS oncogene as a target gene, two types of molecular beacons (MBs) based on either phosphoth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6864f731f45213924bd2a040f652903a
https://doi.org/10.1021/mp200505k

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Radio Frequency-Microchannels for Transdermal Delivery: Characterization of Skin Recovery and Delivery Window

Autor: Meir Stern, Hagit Sacks, Galit Levin, Yossi Kam, Keren Mevorat Kaplan

Publikováno v: Pharmacology & Pharmacy. :20-28

Transdermal delivery through Radio-Frequency-MicroChannels (RF-MCs) was proven to be a promising delivery method for hydrophilic drugs and macromolecules that must be injected. An important issue in assessing this technology is the life span of the m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4e2d8901bf467503928be68cfb9c52d4
https://doi.org/10.4236/pp.2012.31004

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Detection of a long non-coding RNA (CCAT1) in living cells and human adenocarcinoma of colon tissues using FIT–PNA molecular beacons

Autor: Eylon Yavin, Abraham Rubinstein, HongGuang Pan, Ali O. Gure, Ilana Ariel, Shankar Naik, Yossi Kam, Alexander Stojadinovic, David Halle, Victoria Tsivin, Aviram Nissan, Irena Djavsarov

Publikováno v: Cancer Letters

Although the function and mechanism of action of long non-coding RNAs (lncRNA) is still not completely known, studies have shown their potential role in the control of gene expression and regulation, in cellular proliferation and invasiveness at the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85553acf25b33e817b43b5340d7211cf
https://hdl.handle.net/11693/49186

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Phosphatidylserine containing omega-3 Fatty acids may improve memory abilities in nondemented elderly individuals with memory complaints: results from an open-label extension study

Autor: Veronika Vakhapova, Amos D. Korczyn, Yael Richter, Yael Herzog, Yossi Kam, Tzafra Cohen

Publikováno v: Dementia and geriatric cognitive disorders. 38(1-2)

Background: The present study is an open-label extension (OLE) aimed at evaluating the effect of 100 mg/day of phosphatidylserine enriched with docosahexaenoic acid (PS-DHA) on cognitive performance in nondemented elderly individuals with memory comp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::305e35d8269cb19075da37865b6fdcba
https://pubmed.ncbi.nlm.nih.gov/24577097

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The relative roles of charge and a recognition peptide in luminal targeting of colorectal cancer by fluorescent polyacrylamide

Autor: Aviram Nissan, Meital Bloch, Dorit Moradov, Eylon Yavin, Ilana Ariel, Abraham Rubinstein, Yossi Kam

Publikováno v: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 47(5)

Real time detection of biomarkers at the mucosal level is imperative for the prevention and efficient treatment of colorectal cancer. Cationized polyacrylamide (CPAA) with increasing charge densities was prepared by radical polymerization of acrylami

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58cf9fedb34529780216a61c030ab289
https://pubmed.ncbi.nlm.nih.gov/23022517

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