Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Yossi Gottfried"'
Autor:
Sarit Larisch, Assaf Friedler, Gil Shalev, Marie-Jeanne Carp, Inbal Maniv, Dotan Zuri, Tali Lev, Yossi Gottfried, Tali-Haviv Reingewertz, Natalia Edison
PDF file - 2.2MB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29d158f29a0b3df07bd431ba879d77d2
https://doi.org/10.1158/1078-0432.22444232.v1
https://doi.org/10.1158/1078-0432.22444232.v1
Autor:
Sarit Larisch, Assaf Friedler, Gil Shalev, Marie-Jeanne Carp, Inbal Maniv, Dotan Zuri, Tali Lev, Yossi Gottfried, Tali-Haviv Reingewertz, Natalia Edison
Purpose: XIAP [X-linked inhibitor of apoptosis (IAP) protein] is the best characterized mammalian caspase inhibitor. XIAP is frequently overexpressed in a variety of human tumors, and genetic inactivation of XIAP in mice protects against lymphoma. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::482ec3cd072044d896c584286b229916
https://doi.org/10.1158/1078-0432.c.6520109.v1
https://doi.org/10.1158/1078-0432.c.6520109.v1
Autor:
Sarit Larisch, Assaf Friedler, Gil Shalev, Marie-Jeanne Carp, Inbal Maniv, Dotan Zuri, Tali Lev, Yossi Gottfried, Tali-Haviv Reingewertz, Natalia Edison
PDF file - 1.5MB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c6737ec3b6935a6ffe8d0e4e2c64230
https://doi.org/10.1158/1078-0432.22444229.v1
https://doi.org/10.1158/1078-0432.22444229.v1
Autor:
Ronald G. Udasin, Yossi Gottfried, Tamar Ziv, Aaron Ciechanover, Bertrand Fabre, Beatrice Bercovich
Publikováno v:
Biochemical and biophysical research communications. 558
The NF-κB transcription factor is involved in inflammation and cell proliferation, survival, and transformation. It is a heterodimer made of p50 or p52 and a member of the Rel family of proteins. p50 and p52 are derived from limited ubiquitin- and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9d0e24dc6e8c67c76343224f1ab2957
https://pubmed.ncbi.nlm.nih.gov/32933748
https://pubmed.ncbi.nlm.nih.gov/32933748
Autor:
Tali Lev, Yossi Gottfried, Anna Shekhtman, Natalia Edison, Hedva Gonen, Sarit Larisch, Bavat Bornstein, Krishnaraj Rajalingam
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 44:489-495
ARTS (Sept4_i2) is a mitochondrial pro-apoptotic tumor suppressor protein. In response to apoptotic signals, ARTS translocates to the cytosol where it promotes caspase activation through caspase de-repression and proteasome mediated degradation of X-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e60ba85db3bb002a93547ed477d26e0c
https://doi.org/10.1016/j.biocel.2011.12.005
https://doi.org/10.1016/j.biocel.2011.12.005
Autor:
Fabian Glaser, Anna Shekhtman, Bavat Bornstein, Yossi Gottfried, Sarit Larisch, Tali Lev, Natalia Edison
Publikováno v:
Apoptosis. 16:869-881
ARTS (Sept4_i2), is a pro-apoptotic protein localized at the mitochondria of living cells. In response to apoptotic signals, ARTS rapidly translocates to the cytosol where it binds and antagonizes XIAP to promote caspase activation. However, the mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3de281e9a3da96f0e489d55e28385cc6
https://doi.org/10.1007/s10495-011-0622-0
https://doi.org/10.1007/s10495-011-0622-0
Publikováno v:
The EMBO Journal. 23:1627-1635
ARTS is an unusual septin-like mitochondrial protein that was originally shown to mediate TGF-beta-induced apoptosis. Recently, we found that ARTS is also important for cell killing by other pro-apoptotic factors, such as arabinoside, etoposide, stau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec340a7b6da55833ece987f1762dedd8
https://doi.org/10.1038/sj.emboj.7600155
https://doi.org/10.1038/sj.emboj.7600155
Autor:
Sarit Larisch, Zipora Kra-Oz, Eli Khankin, Yardena Segev, Yossi Gottfried, Michal Yalon-Hacohen, Rachel Ofir, Karl Skorecki, Shraga Blazer
Publikováno v:
Biochemical and Biophysical Research Communications. 296:93-101
Primary human cells enter senescence after a characteristic number of population doublings (PDs). In the current study, human skin fibroblasts were propagated in culture under 5.5mM glucose (normoglycemia); addition of 16.5mM D-glucose to a concentra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fc8320200f00bc3f62dedbaf805cb63
https://doi.org/10.1016/s0006-291x(02)00818-5
https://doi.org/10.1016/s0006-291x(02)00818-5
Publikováno v:
Schizophrenia research. 96(1-3)
Schizophrenic brains exhibit various neuro-pathological changes in size, volume and structure as compared to normal brains. These structural abnormalities could be the result of apoptotic cell death. ARTS/Sept4 protein plays an important role in indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9a4190ef3da4ef5a0f5190ba853a545
https://pubmed.ncbi.nlm.nih.gov/17644312
https://pubmed.ncbi.nlm.nih.gov/17644312
Autor:
David Danielpour, Anita B. Roberts, Rina Timberg, Youngsuk Yi, Hedviga Kerner, Hermann Steller, Sarah Eimerl, Sarit Larisch, Colin S. Duckett, Yossi Gottfried, W. Tony Parks, Rona Lotan, Stephanie Birkey Reffey, Robert J. Lechleider, Joseph Orly, Mark P. de Caestecker, Naomi Book-Melamed, Seong-Jin Kim
Publikováno v:
Nature cell biology. 2(12)
Here we describe a protein product of the human septin H5/PNUTL2/CDCrel2b gene, which we call ARTS (for apoptosis-related protein in the TGF-beta signalling pathway). ARTS is expressed in many cells and acts to enhance cell death induced by TGF-beta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c13a3a68219899c0c0f1d7c95a2670c
https://pubmed.ncbi.nlm.nih.gov/11146668
https://pubmed.ncbi.nlm.nih.gov/11146668