Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Yosra Aljawai"'
Autor:
Oren Pasvolsky, Zhongya Wang, Denái R. Milton, Mark R. Tanner, Qaiser Bashir, Samer Srour, Neeraj Saini, Paul Lin, Jeremy Ramdial, Yago Nieto, Guilin Tang, Partow Kebriaei, Yosra Aljawai, Hina N. Khan, Hans C. Lee, Christine Ye, Krina K. Patel, Sheeba K. Thomas, Robert Z. Orlowski, Elizabeth J. Shpall, Richard E. Champlin, Muzaffar H. Qazilbash
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-7 (2024)
Abstract Autologous stem cell transplantation (autoHCT) is considered standard of care for newly diagnosed multiple myeloma (MM). Although most patients eventually progress after autoHCT, a small proportion achieve a durable response. In this retrosp
Externí odkaz:
https://doaj.org/article/3d1f121b74294e0b9db9cfd7898d3a03
Autor:
Oren Pasvolsky, Sassine Ghanem, Denái R. Milton, Mikael Rauf, Mark R. Tanner, Qaiser Bashir, Samer Srour, Neeraj Saini, Paul Lin, Jeremy Ramdial, Yago Nieto, Guilin Tang, Yosra Aljawai, Hina N. Khan, Partow Kebriaei, Hans C. Lee, Krina K. Patel, Sheeba K. Thomas, Donna M. Weber, Robert Z. Orlowski, Elizabeth J. Shpall, Richard E. Champlin, Muzaffar H. Qazilbash
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract The prognostic impact of additional copies of chromosome 1q (1q + ) on outcomes of newly-diagnosed multiple myeloma (NDMM) patients undergoing autologous transplantation (autoSCT) is unclear. We conducted a retrospective single-center analys
Externí odkaz:
https://doaj.org/article/2b3316c0594542dcb9798be18ab86993
Autor:
Yuji Mishima, Bruno Paiva, Jiantao Shi, Jihye Park, Salomon Manier, Satoshi Takagi, Mira Massoud, Adriana Perilla-Glen, Yosra Aljawai, Daisy Huynh, Aldo M. Roccaro, Antonio Sacco, Marzia Capelletti, Alexandre Detappe, Diego Alignani, Kenneth C. Anderson, Nikhil C. Munshi, Felipe Prosper, Jens G. Lohr, Gavin Ha, Samuel S. Freeman, Eliezer M. Van Allen, Viktor A. Adalsteinsson, Franziska Michor, Jesus F. San Miguel, Irene M. Ghobrial
Publikováno v:
Cell Reports, Vol 19, Iss 1, Pp 218-224 (2017)
The development of sensitive and non-invasive “liquid biopsies” presents new opportunities for longitudinal monitoring of tumor dissemination and clonal evolution. The number of circulating tumor cells (CTCs) is prognostic in multiple myeloma (MM
Externí odkaz:
https://doaj.org/article/0ab1ac700cc547768b8dbcbc3419651a
Autor:
Juliette M Bouyssou, Chia-Jen Liu, Mark Bustoros, Romanos Sklavenitis-Pistofidis, Yosra Aljawai, Salomon Manier, Amir Yosef, Antonio Sacco, Katsutoshi Kokubun, Shokichi Tsukamoto, Adriana Perilla Glen, Daisy Huynh, Jorge J Castillo, Steven P Treon, Véronique Leblond, Olivier Hermine, Aldo M Roccaro, Irene M Ghobrial, Marzia Capelletti
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0204589 (2018)
Waldenström Macroglobulinemia (WM) is a low-grade B-cell lymphoma characterized by disease progression from IgM MGUS to asymptomatic and then symptomatic disease states. We profiled exosomes from the peripheral blood of patients with WM at different
Externí odkaz:
https://doaj.org/article/600097cc443b4097b787bc4abb1d1891
Autor:
Aldo M. Roccaro, Yuji Mishima, Antonio Sacco, Michele Moschetta, Yu-Tzu Tai, Jiantao Shi, Yong Zhang, Michaela R. Reagan, Daisy Huynh, Yawara Kawano, Ilyas Sahin, Marco Chiarini, Salomon Manier, Michele Cea, Yosra Aljawai, Siobhan Glavey, Elizabeth Morgan, Chin Pan, Franziska Michor, Pina Cardarelli, Michelle Kuhne, Irene M. Ghobrial
Publikováno v:
Cell Reports, Vol 12, Iss 4, Pp 622-635 (2015)
Extra-medullary disease (EMD) in multiple myeloma (MM) is associated with poor prognosis and resistance to chemotherapy. However, molecular alterations that lead to EMD have not been well defined. We developed bone marrow (BM)- and EMD-prone MM synge
Externí odkaz:
https://doaj.org/article/c17cc3846a7d44b0a97692c30372fb41
Autor:
Irene M. Ghobrial, Alec C. Kimmelman, Aldo M. Roccaro, John M. Asara, Yuji Mishima, Yosra Aljawai, Antonio Sacco, Michele Moschetta, Daisy Huynh, Patricia Maiso
Supplemental Figure 1. Hypoxia-induced drug resistance on MM cells. Supplemental Figure 2. HK2, PFKFB3, PFKFB4 and LDHA expression in MM cell lines. Supplemental Figure 3. (A-B) HIF1A expression in MM1S-shHIF1A. (C) HIF2A expression in MM1S-shHIF2A.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b64b6fafdb369aa7663994c4d2dea9f0
https://doi.org/10.1158/0008-5472.22405524
https://doi.org/10.1158/0008-5472.22405524
Autor:
Franziska Michor, Irene M. Ghobrial, Jiantao Shi, Kenneth C. Anderson, Felipe Prosper, Jesús F. San Miguel, Bruno Paiva, Samuel S. Freeman, Alexandre Detappe, Yuji Mishima, Satoshi Takagi, Aldo M. Roccaro, Salomon Manier, Adriana Perilla-Glen, Gavin Ha, Nikhil C. Munshi, Diego Alignani, Jihye Park, Marzia Capelletti, Daisy Huynh, Antonio Sacco, Yosra Aljawai, Eliezer M. Van Allen, Viktor A. Adalsteinsson, Jens G. Lohr, Mira Massoud
Publikováno v:
Cell Reports, Vol 19, Iss 1, Pp 218-224 (2017)
Cell Reports
Cell reports
Dadun. Depósito Académico Digital de la Universidad de Navarra
instname
Elsevier
Cell Reports
Cell reports
Dadun. Depósito Académico Digital de la Universidad de Navarra
instname
Elsevier
The development of sensitive and non-invasive “liquid biopsies” presents new opportunities for longitudinal monitoring of tumor dissemination and clonal evolution. The number of circulating tumor cells (CTCs) is prognostic in multiple myeloma (MM
Autor:
Angelo Vacca, Luis Palomera, Yawara Kawano, Irene M. Ghobrial, Marta Chesi, Antonio Sacco, Siobhan Glavey, Michele Moschetta, Ilyas Sahin, Felipe Prosper, Bruno Paiva, Leif Bergsagel, Matteo Bellone, Salomon Manier, Jiantao Shi, Yosra Aljawai, Michaela R. Reagan, Aldo M. Roccaro, Arianna Calcinotto, Yuji Mishima, C Unitt
Publikováno v:
Leukemia. 30:1103-1115
The role of endothelial progenitor cell (EPC)-mediated vasculogenesis in hematological malignancies is not well explored. Here, we showed that EPCs are mobilized from the bone marrow (BM) to the peripheral blood at early stages of multiple myeloma (M
Autor:
Michele Moschetta, Irene M. Ghobrial, Michelle Kuhne, Salomon Manier, Elizabeth A. Morgan, Michele Cea, Ilyas Sahin, Yu-Tzu Tai, Jiantao Shi, Franziska Michor, Aldo M. Roccaro, Yuji Mishima, Yong Zhang, Daisy Huynh, Siobhan Glavey, Michaela R. Reagan, Yosra Aljawai, Chin Pan, Yawara Kawano, Marco Chiarini, Pina M. Cardarelli, Antonio Sacco
Publikováno v:
Cell Reports, Vol 12, Iss 4, Pp 622-635 (2015)
Extra-medullary disease (EMD) in Multiple Myeloma (MM) is associated with poor prognosis and resistance to chemotherapy. However, molecular alterations that lead to EMD have not been well defined. We developed bone marrow (BM)- and EMD-prone MM synge
Autor:
Patricia Maiso, John M. Asara, Aldo M. Roccaro, Irene M. Ghobrial, Daisy Huynh, Alec C. Kimmelman, Yuji Mishima, Yosra Aljawai, Antonio Sacco, Michele Moschetta
Publikováno v:
Cancer Research. 75:2071-2082
Drug resistance remains a major clinical challenge for cancer treatment. Multiple myeloma is an incurable plasma cell cancer selectively localized in the bone marrow. The main cause of resistance in myeloma is the minimal residual disease cells that