Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Yoshiyuki WAKABAYASHI"'
Autor:
Xiaoling Zhang, Jeroen G. J. van Rooij, Yoshiyuki Wakabayashi, Shih-Jen Hwang, Yanqin Yang, Mohsen Ghanbari, Daniel Bos, BIOS Consortium, Daniel Levy, Andrew D. Johnson, Joyce B. J. van Meurs, Maryam Kavousi, Jun Zhu, Christopher J. O’Donnell
Publikováno v:
BMC Medical Genomics, Vol 14, Iss 1, Pp 1-17 (2021)
Abstract Background Coronary artery calcification (CAC) is a noninvasive measure of coronary atherosclerosis, the proximal pathophysiology underlying most cases of myocardial infarction (MI). We sought to identify expression signatures of early MI an
Externí odkaz:
https://doaj.org/article/b7211bfdee3c4baf8f459b842514e5fc
Autor:
Julian C Lui, Youn Hee Jee, Presley Garrison, James R Iben, Shanna Yue, Michal Ad, Quang Nguyen, Bijal Kikani, Yoshiyuki Wakabayashi, Jeffrey Baron
Publikováno v:
PLoS Biology, Vol 16, Iss 7, p e2005263 (2018)
Bones at different anatomical locations vary dramatically in size. For example, human femurs are 20-fold longer than the phalanges in the fingers and toes. The mechanisms responsible for these size differences are poorly understood. Bone elongation o
Externí odkaz:
https://doaj.org/article/5c6aa04e995a44a1aedfff68841de73b
Autor:
Xiaoling Zhang, Jeroen G. J. van Rooij, Yoshiyuki Wakabayashi, Shih-Jen Hwang, Yanqin Yang, Mohsen Ghanbari, Daniel Bos, BIOS Consortium, Daniel Levy, Andrew D. Johnson, Joyce B. J. van Meurs, Maryam Kavousi, Jun Zhu, Christopher J. O’Donnell
Publikováno v:
BMC Medical Genomics
BMC Medical Genomics, 14(1):45. BioMed Central Ltd.
BMC Medical Genomics, Vol 14, Iss 1, Pp 1-17 (2021)
BMC Medical Genomics, 14(1):45. BioMed Central Ltd.
BMC Medical Genomics, Vol 14, Iss 1, Pp 1-17 (2021)
Background Coronary artery calcification (CAC) is a noninvasive measure of coronary atherosclerosis, the proximal pathophysiology underlying most cases of myocardial infarction (MI). We sought to identify expression signatures of early MI and subclin
Autor:
Jun Zhu, Shigetoshi Yokoyama, Tsubasa Murata, Shioko Kimura, Wenjing Yang, Yoshiyuki Wakabayashi, Masaaki Miyakoshi, Yoshinori Takizawa, Kunio Nagashima, Yan Cai, Suguru Hayase, Manabu Iwadate
Publikováno v:
Thyroid. 27:460-474
Studies of thyroid stem/progenitor cells have been hampered due to the small organ size and lack of tissue, which limits the yield of these cells. A continuous source that allows the study and characterization of thyroid stem/progenitor cells is desi
Publikováno v:
Landscape Research Japan Online. 10:31-36
Autor:
Kazuyasu Sakaguchi, Yubo Zhang, Takashi Fujita, Yoshiyuki Wakabayashi, Keiko Ozato, Anup Dey, Rui Kamada, Jun Zhu, Mira C. Patel, Ryota Ouda, Yanqin Yang, Tomohiko Tamura, Wenjing Yang
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 115(39)
Epigenetic memory for signal-dependent transcription has remained elusive. So far, the concept of epigenetic memory has been largely limited to cell-autonomous, preprogrammed processes such as development and metabolism. Here we show that IFN beta st
Autor:
Klaus Okkenhaug, Yuka Kanno, Luca Gattinoni, Han-Yu Shih, Peng Li, Giulia Fabozzi, Kylie M. Quinn, Yun Ji, Derek C. Macallan, Jun Zhu, Yoshiyuki Wakabayashi, Shashank J. Patel, Warren J. Leonard, Robert L. Eil, Akihiko Muto, Zhiya Yu, Christopher A. Klebanoff, Kazuhiko Igarashi, Douglas C. Palmer, Rosanne Spolski, Rahul Roychoudhuri, Jenny H. Pan, David Clever, Madhusudhanan Sukumar, Nicholas P. Restifo, John J. O'Shea
Publikováno v:
Nature immunology
T cell antigen receptor (TCR) signaling drives distinct responses depending upon the differentiation state and context of CD8+ T cells. We hypothesized that access of signal-dependent transcription factors (TFs) to enhancers is dynamically regulated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9b64fd302e6120de4824520677dca2b
Autor:
Olga Vitseva, Nada Esa, David D. McManus, Yanqin Yang, Yoshiyuki Wakabayashi, Andrew D. Johnson, John D. Eicher, Jane E. Freedman, Jun Zhu
Publikováno v:
Platelets. 27:230-239
Transcripts in platelets are largely produced in precursor megakaryocytes but remain physiologically active as platelets translate RNAs and regulate protein/RNA levels. Recent studies using transcriptome sequencing (RNA-seq) characterized the platele
Autor:
Eilene Duberow, Alexander Meissner, Derek T. Peters, Poching Liu, Jihoon Choi, Xiaoling Zhang, Curtis R. Warren, Max Friesen, Mary H.C. Florido, Caroline E. Becker, Chad A. Cowan, Jun Zhu, Fang Xia, Robert E. Gerszten, Sekar Kathiresan, Xu Shi, Lauren Comisar, Ramachandran S. Vasan, Laurence Daheron, Alexander M. Tsankov, Jennifer Shay, Yoshiyuki Wakabayashi, Kiran Musunuru, John F. O'Sullivan, Jordan Morningstar, Rahul C. Deo, Xin Jiang, Christopher J. O'Donnell
Publikováno v:
Cell Stem Cell
Genome-wide association studies (GWAS) have highlighted a large number of genetic variants with potential disease association, but functional analysis remains a challenge. Here we describe an approach to functionally validate identified variants thro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16a79878e8d6e4ea6c9980bcc5259fa5
https://hdl.handle.net/11858/00-001M-0000-002D-DCED-911858/00-001M-0000-002D-DCEF-5
https://hdl.handle.net/11858/00-001M-0000-002D-DCED-911858/00-001M-0000-002D-DCEF-5
Autor:
Yoshiyuki Wakabayashi, Irene Riz, Robert G. Hawley, Jun Zhu, Louis DePalma, Wenjing Yang, Teresa S. Hawley, Weiqun Peng, Young-Tae Chang
Publikováno v:
American Journal of Hematology. 88:265-272
Multiple myeloma (MM) is characterized by the malignant expansion of differentiated plasma cells. Although many chemotherapeutic agents display cytotoxic activity toward MM cells, patients inevitably succumb to their disease because the tumor cells b