Zobrazeno 1 - 10
of 136
pro vyhledávání: '"Yoshiyuki Rikitake"'
Autor:
Toru Tanaka, Naoto Sasaki, Aga Krisnanda, Masakazu Shinohara, Hilman Zulkifli Amin, Sayo Horibe, Ken Ito, Motoaki Iwaya, Atsushi Fukunaga, Ken‐ichi Hirata, Yoshiyuki Rikitake
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 2 (2024)
Background Ultraviolet B (UV‐B) irradiation is an effective treatment for human cutaneous disorders and was shown to reduce experimental atherosclerosis by attenuating immunoinflammatory responses. The aim of this study was to clarify the effect of
Externí odkaz:
https://doaj.org/article/74fcc8bc176745c2b3ba9232dff9f5b7
Autor:
Kazuyuki Kasahara, Naoto Sasaki, Hilman Zulkifli Amin, Toru Tanaka, Sayo Horibe, Tomoya Yamashita, Ken-ichi Hirata, Yoshiyuki Rikitake
Publikováno v:
Heliyon, Vol 8, Iss 7, Pp e09981- (2022)
Compelling evidence suggests a crucial role for Foxp3+ regulatory T cells (Tregs) in the control of atherosclerosis. Although suppression of pro-inflammatory CD4+ T cell immune responses is supposed to be important for athero-protective action of Fox
Externí odkaz:
https://doaj.org/article/757cab1f1efd4d83b12af3d69ef62cb4
Publikováno v:
Journal of Clinical Medicine, Vol 10, Iss 24, p 5907 (2021)
Atherosclerotic diseases, including ischemic heart disease and stroke, are a main cause of mortality worldwide. Chronic vascular inflammation via immune dysregulation is critically involved in the pathogenesis of atherosclerosis. Accumulating evidenc
Externí odkaz:
https://doaj.org/article/57bc300a95f54a0ea0f8a96977b868cc
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-9 (2018)
Abstract Background Exosomes, small-membrane vesicles, are secreted by cells and include several types of proteins and nucleic acids. Exosomes transfer cellular information derived from donor cells and are involved in various physiological and pathol
Externí odkaz:
https://doaj.org/article/19199d62f4b84482b65132dfdbeb671a
Autor:
Tomohiro Hayashi, Naoto Sasaki, Tomoya Yamashita, Taiji Mizoguchi, Takuo Emoto, Hilman Zulkifli Amin, Keiko Yodoi, Takuya Matsumoto, Kazuyuki Kasahara, Naofumi Yoshida, Tokiko Tabata, Naoki Kitano, Atsushi Fukunaga, Chikako Nishigori, Yoshiyuki Rikitake, Ken‐ichi Hirata
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 9 (2017)
BackgroundPathogenic immune responses are known to play an important role in abdominal aortic aneurysm (AAA) development. Ultraviolet B (UVB) irradiation has been demonstrated to have therapeutic potential not only for cutaneous diseases but also for
Externí odkaz:
https://doaj.org/article/df3149403569467c9cb843a2131dc221
Autor:
Shoji Kawauchi, Sayo Horibe, Naoto Sasaki, Toshihito Tanahashi, Shigeto Mizuno, Tsuneo Hamaguchi, Yoshiyuki Rikitake
Publikováno v:
Marine Drugs, Vol 17, Iss 2, p 104 (2019)
Nonalcoholic steatohepatitis (NASH) progresses from nonalcoholic fatty liver disease (NAFLD); however, efficacious drugs for NASH treatment are lacking. Sodium alginate (SA), a soluble dietary fiber extracted from brown algae, could protect the small
Externí odkaz:
https://doaj.org/article/2c938b7bdf25412bb72cd2956e540f33
Autor:
Shota Yamana, Amina Tokiyama, Kiyohito Mizutani, Ken-ichi Hirata, Yoshimi Takai, Yoshiyuki Rikitake
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0124259 (2015)
Contact inhibition of cell movement and proliferation is critical for proper organogenesis and tissue remodeling. We show here a novel regulatory mechanism for this contact inhibition using cultured vascular endothelial cells. When the cells were con
Externí odkaz:
https://doaj.org/article/2f7ec5b8b48745ea9cc666ceb859dcf2
Autor:
Junya Sato, Mitsuo Kinugasa, Seimi Satomi-Kobayashi, Kinta Hatakeyama, Aaron J Knox, Yujiro Asada, Margaret E Wierman, Ken-ichi Hirata, Yoshiyuki Rikitake
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107236 (2014)
Identification of the regulators of vascular inflammation is important if we are to understand the molecular mechanisms leading to atherosclerosis and consequent ischemic heart disease, including acute myocardial infarction. Gene polymorphisms in fam
Externí odkaz:
https://doaj.org/article/497e48f693d7428e943bf510647afebe
Autor:
Shoji Kawauchi, Taiji Mizoguchi, Sayo Horibe, Toru Tanaka, Naoto Sasaki, Koji Ikeda, Noriaki Emoto, Ken‐ichi Hirata, Yoshiyuki Rikitake
Publikováno v:
Glia. 71:467-479
In the brain, neurons, glial cells, vascular endothelial cells (ECs), and mural cells form a functional structure referred to as the neurovascular unit (NVU). The functions of the NVU become impaired with aging. To gain insight into the mechanism und
Autor:
Yoshiyuki Rikitake
Publikováno v:
The Journal of Biochemistry. 172:337-340
For proper intracellular vesicle transport, it is essential for transport vesicle membranes to fuse with the appropriate target membranes. Ykt6 is a SNARE protein with functions in diverse vesicle transport pathways, including secretory, endocytotic