Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Yoshiyuki Ohsawa"'
Autor:
Takashi Ueno, Hikari Taka, Reiko Mineki, Junji Ezaki, Yoshiyuki Ohsawa, Eiki Kominami, Masato Koike, Yasuo Uchiyama, Kimie Murayama, Mitsue Takeda-Ezaki
Publikováno v:
Journal of Neurochemistry. 87:1296-1308
Juvenile neuronal ceroid lipofuscinosis (JNCL) is an autosomal recessively inherited lysosomal storage disease involving a mutation in the CLN3 gene. The sequence of CLN3 was determined in 1995; however, the localization of the CLN3 gene product (Cln
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a63602bd5870f807a391be31cd5a975c
https://doi.org/10.1046/j.1471-4159.2003.02132.x
https://doi.org/10.1046/j.1471-4159.2003.02132.x
Autor:
Shigekazu Nagata, Yasuo Tano, Rie Watanabe-Fukunaga, Hidehiro Fukuyama, Takeshi Morimoto, Nobuyuki Ohguro, Yoshiyuki Ohsawa, Yasuo Uchiyama, Sogo Nishimoto, Noriyasu Hashida, Yutaka Fukuda, Kohki Kawane
Publikováno v:
Nature. 424:1071-1074
The eye lens is composed of fibre cells, which develop from the epithelial cells on the anterior surface of the lens1,2,3. Differentiation into a lens fibre cell is accompanied by changes in cell shape, the expression of crystallins4 and the degradat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01925ee62e5b72ba8925628e2444592e
https://doi.org/10.1038/nature01895
https://doi.org/10.1038/nature01895
Autor:
Hua Wang, Yuko Sakai, Tatsuo Harumi, Masahiro Hosaka, Tsuyoshi Watanabe, Yoshiyuki Ohsawa, Toshiyuki Takeuchi, Yoshiki Hira, Yasuo Uchiyama
Publikováno v:
Journal of Histochemistry & Cytochemistry. 51:227-238
Secretogranin III (SgIII) is one of the acidic secretory proteins, designated as granins, which are specifically expressed in neuronal and endocrine cells. To clarify its precise distribution in the anterior lobe of the rat pituitary gland, we raised
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::479e7aac48f147b77175f678ed1f8a41
https://doi.org/10.1177/002215540305100211
https://doi.org/10.1177/002215540305100211
Autor:
Satoshi Waguri, Yasuo Uchiyama, Satoshi Kametaka, Masahiro Shibata, Masato Koike, Yoshiyuki Ohsawa, Eiki Kominami
Publikováno v:
Archives of Histology and Cytology. 65:219-232
To understand the precise distribution of tripeptidyl peptidase I (TPP-I), a defect of which has been shown to induce late infantile neuronal ceroid lipofuscinosis, various tissues from rats and mice were analyzed using biochemical and immunohistoche
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8330b12936137205a89c9ad4ea1b6dbf
https://doi.org/10.1679/aohc.65.219
https://doi.org/10.1679/aohc.65.219
Autor:
Yasuo Uchiyama, Yuji Tomiyama, Satoshi Waguri, Masaki Wakasugi, Tsuyoshi Watanabe, Masato Koike, Mari Kohmura, Yoshiyuki Ohsawa, Eiki Kominami, Shiro Kanamori
Publikováno v:
Europe PubMed Central
Two mannose 6-phosphate receptors, cation-dependent and -independent receptors (CDMPR and CIMPR), play an important role in the intracellular transport of lysosomal enzymes. To investigate functional differences between the two in vivo, their distrib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48d52a9017fa580a4306b1765ff7deba
https://doi.org/10.1177/002215540104901108
https://doi.org/10.1177/002215540104901108
Autor:
K Nakadate, Akira Kakizuka, Kiyoshi Inoue, Yoshiyuki Ohsawa, A Iwamatsu, Yasuo Uchiyama, A Sinohara, Y Kamei, Yoko Kimura, S Hori, A H Popiel, K Tanaka, Miho Hirabayashi
Publikováno v:
Cell Death & Differentiation. 8:977-984
Neuronal cell death, abnormal protein aggregates, and cytoplasmic vacuolization are major pathologies observed in many neurodegenerative disorders such as the polyglutamine (polyQ) diseases, prion disease, Alzheimer disease, and the Lewy body disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2e7deea046bca720032470e9473e793
https://doi.org/10.1038/sj.cdd.4400907
https://doi.org/10.1038/sj.cdd.4400907
Autor:
Yoshihiro Yayoi, Masayuki Miura, Tsuyoshi Watanabe, Yasuo Uchiyama, Yoshiyuki Ohsawa, Eiki Kominami, Masahiro Shibata, Shiro Kanamori
Publikováno v:
Archives of Histology and Cytology. 64:17-28
CED-9 prevents apoptosis in embryonic cells of Caenorhabditis elegans but not in mammalian cells. We show here that the prevention of apoptosis in mammalian cells requires a CED-3-cleaved form (68-280) of CED-9 which is localized in the inner mitocho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62c9db069cc36c02a137e9e459148142
https://doi.org/10.1679/aohc.64.17
https://doi.org/10.1679/aohc.64.17
Autor:
Yasuo Uchiyama, Atsuo Kawahara, Yusuke Shimizu, Shigekazu Nagata, Yoshiyuki Ohsawa, Hirotaka Matsumura
Publikováno v:
The Journal of Cell Biology
A caspase 8-deficient subline (JB6) of human Jurkat cells can be killed by the oligomerization of Fas-associated protein with death domain (FADD). This cell death process is not accompanied by caspase activation, but by necrotic morphological changes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7995abfca13a9490a81067dc6531e85e
https://doi.org/10.1083/jcb.151.6.1247
https://doi.org/10.1083/jcb.151.6.1247
Autor:
Yasuo Uchiyama, Yoshiyuki Ohsawa, Eiki Kominami, Kyoko Isahara, Tsuyoshi Watanabe, Shiro Kanamori, Monica Lindén, Masahiro Shibata, Takahiro Gotow, O Tokuno, Naoyuki Sato, Yoshihiro Yayoi, Jean-Francois Leterrier
Publikováno v:
Cell Death & Differentiation. 7:666-674
Bcl-2, an anti-apoptotic protein, is believed to be localized in the outer mitochondrial membrane, endoplasmic reticulum, and nuclear envelope. However, Bcl-2 has also been suggested as playing a role in the maintenance of mitochondrial membrane pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::437ae584fee2f103cc3604c2e7af232a
https://doi.org/10.1038/sj.cdd.4400694
https://doi.org/10.1038/sj.cdd.4400694
Autor:
Takahiro Gotow, Tsuyoshi Watanabe, Yasuo Uchiyama, Kazuhiro Ikenaka, Riichi Shibata, Yoshiyuki Ohsawa, Jean François Leterrier, Kyoko Isahara
Publikováno v:
European Journal of Neuroscience. 11:3893-3903
Myelination in the peripheral nervous system is considered to increase the phosphorylation level of neurofilament proteins in the axon, resulting in an increase in axonal calibre. To understand the relationship between myelination and neurofilament p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc2af7772ee49cf955071848bf926b95
https://doi.org/10.1046/j.1460-9568.1999.00820.x
https://doi.org/10.1046/j.1460-9568.1999.00820.x