Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Yoshiyuki Moriguchi"'
Autor:
Hirokazu Sudo, Michinori Hirata, Hirotaka Kanada, Keigo Yorozu, Yoshihito Tashiro, Ken-ichi Serizawa, Kenji Yogo, Motoyuki Kataoka, Yoshiyuki Moriguchi, Nobuhiko Ishizuka
Publikováno v:
Journal of Pharmacological Sciences, Vol 111, Iss 1, Pp 53-59 (2009)
Recent clinical studies on chronic kidney disease (CKD) reported that renal dysfunction was a critical risk factor for cardiovascular events (CVE), which lead us to reconsider the effect of cardioprotective agents on the kidney. Glomerulonephritis, w
Externí odkaz:
https://doaj.org/article/1a56a6cb8d454a61a82f6d64ec1884c0
Autor:
Yusuke Sasaki, Katsuya Ikuta, Hirotaka Kanada, Katsunori Sasaki, Yutaka Kohgo, Yoshihiro Torimoto, Takaaki Hosoki, Yasushi Shimonaka, Yoshiyuki Moriguchi
Publikováno v:
International Journal of Hematology. 99:12-20
Hepcidin, which is mainly produced by the liver, is the key regulator in iron homeostasis. Hepcidin expression is up-regulated by iron loading in vivo, but the mechanism underlying this process is not completely understood. In the present study, we i
Autor:
Keigo Yorozu, Satoshi Takeda, Ken Aizawa, Yoshiyuki Moriguchi, Koichi Endo, Michinori Hirata, Hirotaka Kanada, Yoshihito Tashiro
Publikováno v:
American Journal of Nephrology. 36:419-426
Background/Aims: Recent studies have demonstrated that erythropoiesis-stimulating agents (ESAs) induce a tissue-protective effect in the kidney. In this study, we examined whether continuous erythropoietin receptor activator (CERA), a long-acting ESA
Autor:
Kenichi Serizawa, Ken Aizawa, Keigo Yorozu, Sadahiro Iwabuchi, Kenji Yogo, Yoshiyuki Moriguchi, Yoshihito Tashiro, Hidemitsu Kitamura, Nobuhiko Ishizuka, Takashi Nishimura
Publikováno v:
Biomedical Research. 32:83-90
The pathological influences of inflammation on left ventricular hypertrophy (LVH) were studied in subtotal nephrectomized (SNx) rats after 0.3% NaCl loading for 5 weeks. We found that mild hypertension, increased plasma levels of creatinine, inorgani
Autor:
Shigeki Komoda, Makoto Kozuka, Yuzuru Minamidate, Masayoshi Yamaha, Shingo Nagai, Eizo Hasegawa, Atsushi Kawai, Shinichi Hattori, Yoshiyuki Moriguchi, Masahiro Hasegawa, Masanobu Horie, Kenichi Minoshima
Publikováno v:
Nihon Toseki Igakkai Zasshi. 45:163-169
透析患者のESA反応性には,炎症,栄養状態,二次性副甲状腺機能亢進症,鉄代謝の状態等のさまざまな背景が影響を及ぼすと考えられている.近年,hepcidin-25が造血反応での鉄利用障害
Autor:
Yoshiyuki Moriguchi, Hideki Saito, Hiromitsu Kanamori, Atsushi Ogino, Rumi Maruyama, Genzou Takemura, Toshiaki Takeyama, Akiko Tsujimoto, Itta Kawamura, Shinya Minatoguchi, Takako Fujiwara, Kazuko Goto, Tomonori Kawaguchi, Takatomo Watanabe, Longhu Li, Hisayoshi Fujiwara, Masanori Kawasaki
Publikováno v:
Journal of the American College of Cardiology. 56(23):1949-1958
Objectives We examined the effect of asialoerythropoietin (asialoEPO), a nonerythrogenic derivative of erythropoietin (EPO), on renal dysfunction-associated heart failure. Background Although EPO is known to exert beneficial effects on cardiac functi
Autor:
Toshifumi Sakaguchi, Kazuhiro Shiizaki, Fumie Saji, Tadao Akizawa, Shigeaki Kato, Eiji Kusano, Eiko Nakazawa, Yoshiyuki Moriguchi, Ikuo Imazeki, Ikuji Hatamura
Publikováno v:
Bone. 45:964-971
Vitamin D plays a major role in mineral and skeletal homeostasis through interaction with the nuclear vitamin D receptor (VDR) of target cells. Recent reports have indicated that some cellular effects of vitamin D may occur via alternative signaling
Autor:
Jun-ichi Miyazaki, Yasuko Ishikawa, Junichiro James Kazama, Yoshiyuki Moriguchi, Noboru Higuchi, Makoto Sugawa, Fumitake Gejyo, Ikuo Imazeki, Ken Ataka, Hiroki Maruyama, Susumu Hasegawa, Yumi Ito
Publikováno v:
Human Gene Therapy. 11:429-437
It has been demonstrated that gene transfer by in vivo electroporation of mouse muscle increases the level of gene expression by more than 100-fold over simple plasmid DNA injection. We tested continuous rat erythropoietin (Epo) delivery by this meth
Autor:
Masafumi Fukagawa, Yoshiyuki Moriguchi, Yoshihito Tashiro, Ken Aizawa, Michinori Hirata, Kenichi Serizawa, Kenji Yogo, Satoshi Takeda, Koichi Endo
Publikováno v:
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 28(5)
BACKGROUND Vitamin D deficiency is associated with endothelial dysfunction in type 2 diabetes patients, but the effectiveness of vitamin D supplementation remains controversial. We assessed whether 22-oxacalcitriol (OCT) could prevent endothelial dys
Publikováno v:
Journal of Reproduction and Development. 40:107-116
A decline in fertility rate is observed in aged mice of an inbred IVCS strain. This study was conducted if the rate of in vitro fertilization is also decreased with age. If male and female mice of the same age were used for natural matings, the highe