Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Yoshiyuki Mishima"'
Autor:
Akihiko Oka, Kousaku Kawashima, Kenichi Kishimoto, Satoshi Kotani, Mai Fukunaga, Nobuhiko Fukuba, Yoshiyuki Mishima, Naoki Oshima, Norihisa Ishimura, Muyiwa Awoniyi, Shunji Ishihara
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Fecal calprotectin (FC) is a promising biomarker for diagnosis and treatment of inflammatory bowel disease, ulcerative colitis (UC), and Crohn’s disease. An enzyme immunoassay (EIA) is widely used for FC detection, though the considerable
Externí odkaz:
https://doaj.org/article/0b6eddd18296403b939f53d8d6b20451
Autor:
Kenjiro Matsumoto, Kana Takata, Daisuke Yamada, Haruki Usuda, Koichiro Wada, Maaya Tada, Yoshiyuki Mishima, Shunji Ishihara, Syunji Horie, Akiyoshi Saitoh, Shinichi Kato
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Irritable bowel syndrome (IBS) is the most common functional gastrointestinal disorder. Traumatic stress during adolescence increases the risk of IBS in adults. The aim of this study was to characterize the juvenile social defeat stress (SDS
Externí odkaz:
https://doaj.org/article/4fb9e575fcde4cd0be3226169baa42ca
Autor:
Naoki Oshima, Yoshiyuki Mishima, Kotaro Shibagaki, Kousaku Kawashima, Norihisa Ishimura, Fumiyoshi Ikejiri, Chie Onishi, Takahiro Okada, Masaya Inoue, Ichiro Moriyama, Junji Suzumiya, Yoshikazu Kinoshita, Shunji Ishihara
Publikováno v:
BMC Gastroenterology, Vol 21, Iss 1, Pp 1-7 (2021)
Abstract Background Dasatinib is a second-generation tyrosine kinase inhibitor (TKI) developed for treatment of patients with chronic myeloid leukemia (CML). The drug has been shown to act as a potent multikinase inhibitor by blocking not only the BC
Externí odkaz:
https://doaj.org/article/852456db15cd41d6b298d2b41507975a
Autor:
Yoshiyuki Mishima, Shunji Ishihara
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 19, p 10235 (2021)
Irritable bowel syndrome (IBS) is a chronic functional disorder that affects the gastrointestinal tract. Details regarding the pathogenesis of IBS remain largely unknown, though the dysfunction of the brain-gut-microbiome (BGM) axis is a major etiolo
Externí odkaz:
https://doaj.org/article/21fef190e6a447cfa3e341800727eaae
Autor:
Yoshiyuki Mishima, Shunji Ishihara
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 22, p 8664 (2020)
Irritable bowel syndrome (IBS) is one of the most prevalent functional gastrointestinal disorders, and accumulating evidence gained in both preclinical and clinical studies indicate the involvement of enteric microbiota in its pathogenesis. Gut resid
Externí odkaz:
https://doaj.org/article/ec95f9613e9d4caf90af3baa3685f9bd
Autor:
Nobuhiko Fukuba, Shunji Ishihara, Kousaku Kawashima, Yoshiyuki Mishima, Naoki Oshima, Yoshikazu Kinoshita
Publikováno v:
Intestinal Research, Vol 15, Iss 4, Pp 543-545 (2017)
Externí odkaz:
https://doaj.org/article/236b74abf1bd4a00b8f47433eb7af00e
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 1, Iss 3, Pp 295-310 (2015)
Background & Aims: The regulatory roles of interleukin-10 (IL10)-producing B cells in colitis are not fully understood, so we explored the molecular mechanisms by which these cells modulate mucosal homeostasis. Methods: CD4+ T cells from wild-type (W
Externí odkaz:
https://doaj.org/article/6f13dc50f5bf471ca1d1227964e723fe
Autor:
Nobuhiko Fukuba, Shunji Ishihara, Hiroki Sonoyama, Noritsugu Yamashita, Masahito Aimi, Yoshiyuki Mishima, Tsuyoshi Mishiro, Hiroshi Tobita, Koutarou Shibagaki, Naoki Oshima, Ichiro Moriyama, Kousaku Kawashima, Tatsuya Miyake, Norihisa Ishimura, Shuichi Sato, Yoshikazu Kinoshita
Publikováno v:
Endoscopy International Open, Vol 05, Iss 04, Pp E291-E296 (2017)
Background and study aims Recurrence of common bile duct stones (CBDS) in patients treated with endoscopic sphincterotomy (ES) can lead to deterioration in their quality of life. Although the pathology and related factors are unclear, we speculated t
Externí odkaz:
https://doaj.org/article/899d0683fe5a4a829148140da361db4d
Autor:
Akihiko Oka, Yoshiyuki Mishima, Bo Liu, Jeremy W. Herzog, Erin C. Steinbach, Taku Kobayashi, Scott E. Plevy, R. Balfour Sartor
Publikováno v:
Cells, Vol 8, Iss 10, p 1121 (2019)
The phosphoinositide 3-kinase catalytic subunit p110δ (PI3Kδ) gene maps to a human inflammatory bowel diseases (IBD) susceptibility locus, and genetic deletion of PI3Kδ signaling causes spontaneous colitis in mice. However, little is known regardi
Externí odkaz:
https://doaj.org/article/cc4f1296b76b4c0a8195deab593d7696
Autor:
Yoshiyuki Mishima, Shunji Ishihara, Akihiko Oka, Nobuhiko Fukuba, Naoki Oshima, Hiroki Sonoyama, Noritsugu Yamashita, Yasumasa Tada, Ryusaku Kusunoki, Ichiro Moriyama, Takafumi Yuki, Kousaku Kawashima, Yoshikazu Kinoshita
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146191 (2016)
BACKGROUND:CD5+ B cells are a type of regulatory immune cells, though the involvement of this B cell subset in intestinal inflammation and immune regulation is not fully understood. METHODS:We examined the distribution of CD5+ B cells in various mous
Externí odkaz:
https://doaj.org/article/e2e9acdb1be34e07a8e5487cd6ce7240