Zobrazeno 1 - 10 of 155 pro vyhledávání: '"Yoshiyuki Koyama"'
1
Akademický článek
Water-Absorbing Bioadhesive Poly(Acrylic Acid)/Polyvinylpyrrolidone Complex Sponge for Hemostatic Agents
Autor: Tomoko Ito, Shingo Yamaguchi, Daisuke Soga, Keisuke Ueda, Takayuki Yoshimoto, Yoshiyuki Koyama
Publikováno v: Bioengineering, Vol 9, Iss 12, p 755 (2022)
Background: Poly(acrylic acid) (PAA) is a water-soluble synthetic polymer with tissue-adhesive properties. When PAA is mixed with polyvinylpyrrolidone (PVP) in water, it forms a water-insoluble precipitate that neither swells nor adheres to tissues.
Externí odkaz: https://doaj.org/article/db70a940d567498e9ad172d1f9228a0e
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2
Akademický článek
Preparation of a Bioadhesive Poly(Acrylic Acid)/Polyvinylpyrrolidone Complex Gel and Its Clinical Effect on Dental Hemostasis
Autor: Tomoko Ito, Shingo Yamaguchi, Daisuke Soga, Takayuki Yoshimoto, Yoshiyuki Koyama
Publikováno v: Gels, Vol 8, Iss 8, p 462 (2022)
Poly(acrylic acid) (PAA) is a water-soluble synthetic polymer that exhibits bioadhesive properties and has been applied in various novel medical devices, such as drug-delivery carriers and hemostatic agents. PAA forms a water-insoluble complex when m
Externí odkaz: https://doaj.org/article/c16aef171e084ab3bb429c7dd2ae8f03
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3
Akademický článek
Microbial Antigen-Presenting Extracellular Vesicles Derived from Genetically Modified Tumor Cells Promote Antitumor Activity of Dendritic Cells
Autor: Tomoko Ito, Kikuya Sugiura, Aya Hasegawa, Wakana Ouchi, Takayuki Yoshimoto, Izuru Mizoguchi, Toshio Inaba, Katsuyuki Hamada, Masazumi Eriguchi, Yoshiyuki Koyama
Publikováno v: Pharmaceutics, Vol 13, Iss 1, p 57 (2021)
Tumor-derived extracellular vesicles (EVs), as tumor vaccines, carry tumor-associated antigens (TAAs), and were expected to transfer TAAs to antigen-presenting cells. However, treatment with tumor-derived EVs exhibited no obvious antitumor effect on
Externí odkaz: https://doaj.org/article/0cd0b7d8775b4d938f809aa0add8bc9f
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4
Akademický článek
Highly Effective Non-Viral Antitumor Gene Therapy System Comprised of Biocompatible Small Plasmid Complex Particles Consisting of pDNA, Anionic Polysaccharide, and Fully Deprotected Linear Polyethylenimine
Autor: Yoshiyuki Koyama, Kikuya Sugiura, Chieko Yoshihara, Toshio Inaba, Tomoko Ito
Publikováno v: Pharmaceutics, Vol 7, Iss 3, Pp 152-164 (2015)
We have reported that ternary complexes of plasmid DNA with conventional linear polyethylenimine (l-PEI) and certain polyanions were very stably dispersed, and, with no cryoprotectant, they could be freeze-dried and re-hydrated without the loss of tr
Externí odkaz: https://doaj.org/article/4af7de40c1144628ace9801f5fe45834
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5
Akademický článek
Novel Antitumor Strategy Utilizing a Plasmid Expressing a Mycobacterium tuberculosis Antigen as a 'Danger Signal' to Block Immune Escape of Tumor Cells
Autor: Yoshiyuki Koyama, Chieko Yoshihara, Tomoko Ito
Publikováno v: Pharmaceutics, Vol 7, Iss 3, Pp 165-174 (2015)
Immune escape of tumor cells is one of the main obstacles hindering the effectiveness of cancer immunotherapy. We developed a novel strategy to block immune escape by transfecting tumor cells in vivo with genes of pathogenic antigens from Mycobacteri
Externí odkaz: https://doaj.org/article/9dbd04dcb7584697a260262826b328fc
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6
Akademický článek
Velocity Measurement of Sub-Millimeter-Scale Gas Flow by Spark Tracing Method
Autor: Mitsuhisa ICHIYANAGI, Yoshiyuki KOYAMA, Yohei SATO, Koichi HISHIDA
Publikováno v: Journal of Thermal Science and Technology, Vol 8, Iss 3, Pp 517-532 (2013)
A molecular tagging technique using the spark tracing method has been applied to measure velocity distributions in sub-millimeter-scale gas flows, formed as air jet flows through a sub-millimeter channel. Spark lines are generated by air ionization w
Externí odkaz: https://doaj.org/article/4458c8ff607a4b40bc1859e21afce8fd
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10
Bioadhesive and biodissolvable hydrogels consisting of water‐swellable poly(acrylic acid)/poly(vinylpyrrolidone) complexes
Autor: Kentaro Mori, Kazuya Fujii, Naoki Otani, Tomoko Ito, Yoshiyuki Koyama, Masazumi Eriguchi
Publikováno v: Journal of Biomedical Materials Research Part B: Applied Biomaterials. 108:503-512
Films that can form bioadhesive hydrogels on wet biotissues absorbing blood or body fluids are useful for medical devices such as hemostats, adhesion barriers, wound dressings, and drug release devices. We focused on a hydrogen-bonding polymer comple
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f266498143e3c103d0de579c0f880d4
https://doi.org/10.1002/jbm.b.34407
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