Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Yoshiyasu Ogihara"'
Autor:
Toshihide Nukada, Tadashi Shiotani, Masao Nishimura, Yasuro Ishikawa, Taiji Furukawa, Mitsunobu Yoshii, Shigeo Watabe, Yoshiyasu Ogihara
Publikováno v:
Annals of the New York Academy of Sciences. 1025:389-397
It has recently been reported that nefiracetam, a nootropic agent, is capable of attenuating the development of morphine dependence and tolerance in mice. The mechanism of this antimorphine action is not clear. The present study was designed to addre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a2362ef359672e9a76b6416a759430c
https://doi.org/10.1196/annals.1316.048
https://doi.org/10.1196/annals.1316.048
Autor:
Yasuyuki TAKEDA, Keiichi KAWAGOE, Aki YOKOMIZO, Yoshihiro YOKOMIZO, Toru HOSOKAMI, Yoshimasa SHIMOTO, Yoshiaki TABUCHI, Yoshiyasu OGIHARA, Yuko HONDA, Keiko KAWARABAYASHI, Miki ISERI, Shuichi YOKOHAMA
Publikováno v:
Chemical and Pharmaceutical Bulletin. 47:755-771
In order to improve the biological characteristics of DA-3934 (5), a novel gastrin/cholecystokinin (CCK)-B receptor antagonist, phenoxyacetic acid derivatives replacing the N-methyl-N-phenylcarbamoylmethyl moiety of 5 with various alkyl chains have b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f40ab67adeb5103712825d89a2a0cd8
https://doi.org/10.1248/cpb.47.755
https://doi.org/10.1248/cpb.47.755
Autor:
Haruhiro Higashida, Toshihide Nukada, Kazuyuki Suzuki, Reiko Miura, Yasuo Mori, Taiji Furukawa, Mark Strobeck, Yoshiyasu Ogihara, Tomiko Asano, Mitsunobu Yoshii, Minako Hashii, Rika Morishita
Publikováno v:
Journal of Biological Chemistry. 273:17595-17603
The present study was designed to obtain evidence for direct interactions of G-protein α (Gα) and βγ subunits (Gβγ) with N- (α1B) and P/Q-type (α1A) Ca2+ channels, using synthetic peptides and fusion proteins derived from loop 1 (cytoplasmic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c449e8fd98223de2b1fc74dd87df902
https://doi.org/10.1074/jbc.273.28.17595
https://doi.org/10.1074/jbc.273.28.17595
Autor:
Yoshiyasu Ogihara, Susumu Okabe
Publikováno v:
Japanese Journal of Pharmacology. 61:123-131
Repeated administration of indomethacin delays the healing of acetic acid-induced gastric ulcers in rats, but the underlying mechanism remains unclear. We examined the effect of indomethacin on the contraction of the connective tissue isolated from t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb46efe6098f16f08bb9a7f4bc515a5e
https://doi.org/10.1254/jjp.61.123
https://doi.org/10.1254/jjp.61.123
Publikováno v:
Japanese Journal of Pharmacology. 54:333-338
A crude extract of Crypthecodinium cohnii and its main component, dimethyl-beta-propiothetin, significantly and dose-dependently protected the gastric mucosa against HCl.ethanol-induced lesions in rats. Since indomethacin pretreatment reduced the pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f950de42f5221651ff4581aed1b1de6
https://doi.org/10.1254/jjp.54.333
https://doi.org/10.1254/jjp.54.333
Autor:
Kei-ichi Kawagoe, Toru Hosokami, Yasuyuki Takeda, Yoshiyasu Ogihara, Yoshiaki Tabuchi, Yokomizo Aki, Rira Otsubo, Shuichi Yokohama, Yuko Honda, Yoshihiro Yokomizo, Yoshimasa Shimoto
Publikováno v:
Chemicalpharmaceutical bulletin. 46(6)
A novel series of phenoxyacetic acid derivatives was synthesized based on considerations of the three-dimensional structural similarity of YM022 and RP72540. The gastrin/cholecystokinin (CCK)-B and CCK-A receptor antagonist activities of these compou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97ccf6c810200c83b984bd7e9a0fafc2
https://pubmed.ncbi.nlm.nih.gov/9658573
https://pubmed.ncbi.nlm.nih.gov/9658573
Autor:
Yasuyuki TAKEDA, Keiichi KAWAGOE, Aki YOKOMIZO, Yoshihiro YOKOMIZO, Toru HOSOKAMI, Yoshiyasu OGIHARA, Yuko HONDA, Shuichi YOKOHAMA
Publikováno v:
Chemicalpharmaceutical bulletin. 46(3)
A novel series of phenoxyacetic acid derivatives was synthesized based on considerations of the three-dimensional structural similarity of YM022 and RP72540. The gastrin/cholecystokinin (CCK)-B and CCK-A receptor antagonist activities of these compou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb3b39d475ce697554e274a199a5a257
https://pubmed.ncbi.nlm.nih.gov/9549885
https://pubmed.ncbi.nlm.nih.gov/9549885
Publikováno v:
Sucralfate ISBN: 9780306447402
Sucralfate is one of the best-known drugs which is frequently used for the treatment of peptic ulcers. 1,2 The mechanisms of action of sucralfate have been described in the preceding chapters. In this chapter, a detailed account will be given of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6866fec31bdada96e00f5dc9f234a6dc
https://doi.org/10.1007/978-0-585-32154-7_19
https://doi.org/10.1007/978-0-585-32154-7_19
Autor:
Yoshiyasu Ogihara, Susumu Okabe
Publikováno v:
Japanese journal of pharmacology. 61(2)
Repeated administration of indomethacin or prednisolone for 2 weeks apparently delayed the healing of initial gastric ulcers induced by acetic acid injection in rats. While indomethacin significantly interfered with the healing of partially healed 2-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3253f86d972d9fc4866fca5d36f4ef75
https://pubmed.ncbi.nlm.nih.gov/8459650
https://pubmed.ncbi.nlm.nih.gov/8459650
Autor:
Sumie Muramatsu, Toshiro Shibano, Takako Iijima, Tomoko Shibutani, Yoshiyasu Ogihara, Yuki Kaneda
Publikováno v:
Blood. 106:1875-1875
Introduction: Bleeding risk accompanied with anti-platelet drugs is an ultimate dilemma in the treatment of thrombosis patient. Under high shear condition of blood flow, vWF- and collagen-induced signaling pathways are likely to trigger the platelet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c500192ebe6a52fb2f004c6196d6ad1
https://doi.org/10.1182/blood.v106.11.1875.1875
https://doi.org/10.1182/blood.v106.11.1875.1875