Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Yoshiyasu Ogata"'
Autor:
Rie Shirayama, Harumi Kakuda, Masataka Ishimura, Yoshiyasu Ogata, Yushi Chikasawa, Hideyuki Takedani, Akira Shirahata, Akira Ishiguro, Kiyotaka Isobe, Mitsuhiro Uchiba, Koichi Kusuhara
Publikováno v:
Blood coagulationfibrinolysis : an international journal in haemostasis and thrombosis. 30(8)
The novel agent pd-FVIIa/FX is a 1 : 10 protein weight mixture of activated factor VII (FVIIa) and factor X (FX) derived from donated blood plasma. A phase III clinical trial of pd-FVIIa/FX revealed high efficacy for bleeding episodes in haemophilia
Publikováno v:
Pediatrics international : official journal of the Japan Pediatric Society. 59(2)
Hemophilic pseudotumor is a rare complication, even in patients with severe hemophilia. Herein we report on a case of hemophilic pseudotumor in a patient with mild hemophilia A and allergic rhinitis, initially suspected to be a nasal tumor. The pseud
Autor:
Naohiko Moriguchi, Yuji Miyajima, Kimiaki Uetake, Akira Ohtake, Yatio Ota, Taro Yamazaki, Shouichi Ohga, Masahiko Okada, Tomohito Takimoto, Nozomu Sasaki, Shin Amemiya, Ryuichiro Araki, Yoshiyasu Ogata, Koji Kato, Masanori Nishi, Keigo Hamahata, Kiyoshi Kawakami, Mitsuhiro Fujiwara, Saori Ishii, Hidemi Toyoda, Nobuyuki Miura, Atsushi Shibuya, Shigeru Ohta
Publikováno v:
Pediatrics international : official journal of the Japan Pediatric Society. 59(3)
Background A nationwide, multicenter and observational study was retrospectively conducted to evaluate the clinical utility of cepharanthin (CEP) therapy for pediatric patients with chronic immune thrombocytopenia (ITP). Methods Clinical and laborato
Autor:
Shinsaku Imashuku, Ikuyo Ueda, Eiichi Ishii, Akira Morimoto, Masanori Nishi, Shouichi Ohga, Ken Yamamoto, Takehiko Sasazuki, Masafumi Zaitsu, Hisanori Horiuchi, Masaki Yasukawa, Yoshiyasu Ogata, Toshiro Hara
Publikováno v:
Journal of Human Genetics. 50:600-603
Although mutations of perforin, MUNC13-4 and syntaxin 11 genes have been found in children with familial hemophagocytic lymphohistiocytosis (FHL), the incidence of each genetic subtype varies in different ethnic groups. We evaluated mutations of synt
Publikováno v:
Journal of Biological Chemistry. 278:14978-14984
The c-fps/fes proto-oncogene encodes a 92-kDa protein-tyrosine kinase that is involved in myeloid cell development and function. We have recently shown that expression of an activated allele of Fes (Fes(act)) in monocyte precursors resulted in their
Publikováno v:
Bone. 28:474-483
A member of the tumor necrosis factor (TNF) family, receptor activator of nuclear factor kappaB ligand (RANKL; also known as ODF, OPGL, and TRANCE), plays critical roles in osteoclast differentiation and activation in the presence of macrophage colon
Publikováno v:
Cellular Immunology. 175:67-75
The effects of oral administration of ovalbumin (OVA) on acute OVA-induced arthritis (OIA) in rats, which is mediated by Arthus reaction to the antigen in the joint space, were investigated. The oral administration of OVA before immunization with OVA
Autor:
Shuichi Yamamoto, Miyoko Imayoshi, Manabu Iwanaga, Kazuto Taniguchi, Yuhei Hamasaki, Eiichi Ishii, Yoshiyasu Ogata, Masanori Nishi, Nana Sakai
Publikováno v:
American journal of hematology. 80(1)
Translocation 11q23 and MLL gene rearrangements are commonly observed in acute myeloid leukemia (AML) in association with the myelomonocytic or monocytic feature. We describe a case involving a 15-year-old patient with AML characterized by leukemic c
Autor:
Hidetoshi Takada, Masahiro Sako, Akifumi Sakata, Toshiro Hara, Kenichi Koike, Shouichi Ohga, Takehiko Sasazuki, Hisanori Horiuchi, Kenji Furuno, Shinsaku Imashuku, Akira Morimoto, Masaki Yasukawa, Ken Yamamoto, Yoshiyasu Ogata, Eiichi Ishii, Ikuyo Ueda, Miyoko Imayoshi, Ryutaro Shirakawa, Masafumi Zaitsu
Publikováno v:
Blood. 105(9)
Mutations of the perforin (PRF1) and MUNC13-4 genes distinguish 2 forms of familial hemophagocytic lymphohistiocytosis (FHL2 and FHL3, respectively), but the clinical and biologic correlates of these genotypes remain in question. We studied the prese
Autor:
Masaki Yasukawa, Ken Yamamoto, Eiichi Ishii, Hiroshi Wakiguchi, Shinsaku Imashuku, N. Nakadate, M. Hirose, Masahiro Sako, Yuhei Hamasaki, T. Teramura, Yoshiyasu Ogata, Miyoko Imayoshi, Naoki Sakata, Masafumi Zaitsu
Publikováno v:
Tissue antigens. 64(5)
Mediation of Epstein-Barr virus (EBV)-specific cytotoxicity in T lymphocyte via the perforin/granzyme pathway has been demonstrated; therefore, a study involving cytolytic molecules was essential for the clarification of hemophagocytic lymphohistiocy