Zobrazeno 1 - 10
of 193
pro vyhledávání: '"Yoshiya Shimada"'
Autor:
Takafumi Nakayama, Masaaki Sunaoshi, Yi Shang, Mizuki Takahashi, Takato Saito, Benjamin J Blyth, Yoshiko Amasaki, Kazuhiro Daino, Yoshiya Shimada, Akira Tachibana, Shizuko Kakinuma
Publikováno v:
PLoS ONE, Vol 18, Iss 1, p e0280560 (2023)
Calorie restriction (CR) suppresses not only spontaneous but also chemical- and radiation-induced carcinogenesis. Our previous study revealed that the cancer-preventive effect of CR is tissue dependent and that CR does not effectively prevent the dev
Externí odkaz:
https://doaj.org/article/d593dc7b262f475e8791f1b1924e1242
Autor:
Sae Sakama, Keisuke Kurusu, Mayu Morita, Takashi Oizumi, Shinya Masugata, Shohei Oka, Shinya Yokomizo, Mayumi Nishimura, Takamitsu Morioka, Shizuko Kakinuma, Yoshiya Shimada, Asako J. Nakamura
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
After the Fukushima Daiichi Nuclear Power Plant accident, there is growing concern about radiation-induced carcinogenesis. In addition, living in a long-term shelter or temporary housing due to disasters might cause unpleasant stress, which adversely
Externí odkaz:
https://doaj.org/article/a5f0afbb28bc46d5adcfce26bed4353b
Autor:
Mayumi Nishimura, Kazuhiro Daino, Maki Fukuda, Ikuya Tanaka, Hitomi Moriyama, Kaye Showler, Yukiko Nishimura, Masaru Takabatake, Toshiaki Kokubo, Atsuko Ishikawa, Kazumasa Inoue, Masahiro Fukushi, Shizuko Kakinuma, Tatsuhiko Imaoka, Yoshiya Shimada
Publikováno v:
PLoS ONE, Vol 16, Iss 8, p e0255968 (2021)
Copenhagen rats are highly resistant to mammary carcinogenesis, even after treatment with chemical carcinogens and hormones; most studies indicate that this is a dominant genetic trait. To test whether this trait is also dominant after radiation expo
Externí odkaz:
https://doaj.org/article/f809fc58fb0444b397ec183fc7dd069b
Autor:
Masaaki Sunaoshi, Benjamin J. Blyth, Yi Shang, Chizuru Tsuruoka, Takamitsu Morioka, Mayumi Shinagawa, Mari Ogawa, Yoshiya Shimada, Akira Tachibana, Daisuke Iizuka, Shizuko Kakinuma
Publikováno v:
Biology, Vol 11, Iss 3, p 449 (2022)
The risk of radiation-induced carcinogenesis depends on age at exposure. We previously reported principal causative genes in lymphomas arising after infant or adult exposure to 4-fractionated irradiation as Pten or Ikzf1, respectively, suggesting tha
Externí odkaz:
https://doaj.org/article/34d20e1ece824a28b25eaefa2a5f640a
Autor:
Shino Homma-Takeda, Chiya Numako, Keisuke Kitahara, Takanori Yoshida, Masakazu Oikawa, Yasuko Terada, Toshiaki Kokubo, Yoshiya Shimada
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 19, p 4677 (2019)
Although the kidneys comprise a critical target of uranium exposure, the dynamics of renal uranium distribution have remained obscure. Uranium is considered to function physiologically in the form of uranyl ions that have high affinity for phosphate
Externí odkaz:
https://doaj.org/article/5035613eefdc413a8b660ed0f878f105
Autor:
Masaru Takabatake, Benjamin J Blyth, Kazuhiro Daino, Tatsuhiko Imaoka, Mayumi Nishimura, Masahiro Fukushi, Yoshiya Shimada
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164194 (2016)
Several lines of evidence indicate one's age at exposure to radiation strongly modifies the risk of radiation-induced breast cancer. We previously reported that rat mammary carcinomas induced by pre- and post-pubertal irradiation have distinct gene e
Externí odkaz:
https://doaj.org/article/e16ff4143a364e40b9e5fdeb7b040cab
Autor:
Benjamin J Blyth, Shizuko Kakinuma, Masaaki Sunaoshi, Yoshiko Amasaki, Shinobu Hirano-Sakairi, Kanae Ogawa, Ayana Shirakami, Yi Shang, Chizuru Tsuruoka, Mayumi Nishimura, Yoshiya Shimada
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0130666 (2015)
Monitoring mice exposed to carbon ion radiotherapy provides an indirect method to evaluate the potential for second cancer induction in normal tissues outside the radiotherapy target volume, since such estimates are not yet possible from historical p
Externí odkaz:
https://doaj.org/article/e95c58c780cf4c2fb5189b0c3629c6e8
Autor:
Kazuhiro Daino, Tatsuhiko Imaoka, Takamitsu Morioka, Shusuke Tani, Daisuke Iizuka, Mayumi Nishimura, Yoshiya Shimada
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74013 (2013)
BRIP1 is a DNA helicase that directly interacts with the C-terminal BRCT repeat of the breast cancer susceptibility protein BRCA1 and plays an important role in BRCA1-dependent DNA repair and DNA damage-induced checkpoint control. Recent studies impl
Externí odkaz:
https://doaj.org/article/19b645967b984f8d880a28b2ab0adad7
Autor:
Hisakatsu Nawata, Genro Kashino, Keizo Tano, Kazuhiro Daino, Yoshiya Shimada, Hiroyuki Kugoh, Mitsuo Oshimura, Masami Watanabe
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25319 (2011)
A change in chromosome number, known as aneuploidy, is a common characteristic of cancer. Aneuploidy disrupts gene expression in human cancer cells and immortalized human epithelial cells, but not in normal human cells. However, the relationship betw
Externí odkaz:
https://doaj.org/article/0358b9329afd4f8783c9611da9383958
Autor:
Nishimura, Mayumi, Imaoka, Tatsuhiko, Daino, Kazuhiro, Nishimura, Yukiko, Kokubo, Toshiaki, Takabatake, Masaru, Kakinuma, Shizuko, Shimada, Yoshiya, Mayumi, Nishimura, Tatsuhiko, Imaoka, Kazuhiro, Daino, Yukiko, Nishimura, Toshiaki, Kokubo, Masaru, Takabatake, Shizuko, Kakinuma, Yoshiya, Shimada
Publikováno v:
Anticancer Research. 42(5):2415-2423
Background/Aim: Genetic and environmental factors interact to dictate the risk of cancer, and animal models are expected to provide avenues for identifying such interactions. The aim of the study was to clarify the genetic susceptibility of Copenhage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=jairo_______::d24e9b177192c7ec73ff3286b2c990c5
https://repo.qst.go.jp/records/86160
https://repo.qst.go.jp/records/86160