Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Yoshiya J Matsubara"'
Autor:
Sandeep Ameta, Manoj Kumar, Nayan Chakraborty, Yoshiya J. Matsubara, Prashanth S, Dhanush Gandavadi, Shashi Thutupalli
Publikováno v:
Communications Chemistry, Vol 6, Iss 1, Pp 1-10 (2023)
Abstract Robust localization of self-reproducing autocatalytic chemistries is a key step in the realization of heritable and evolvable chemical systems. While autocatalytic chemical reaction networks already possess attributes such as heritable self-
Externí odkaz:
https://doaj.org/article/56adabf365db48f58f2062f7644616a0
Publikováno v:
Physical Review Research, Vol 5, Iss 1, p 013170 (2023)
An important issue for the origins of life is ensuring the accurate maintenance of information in replicating polymers in the face of inevitable errors. Here, we investigated how this maintenance depends on reaction kinetics by incorporating the elem
Externí odkaz:
https://doaj.org/article/0a2980e21dd74ee99bc50a7494fccddf
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 6, p e1007094 (2019)
The emergence of replicases that can replicate themselves is a central issue in the origin of life. Recent experiments suggest that such replicases can be realized if an RNA polymerase ribozyme is divided into fragments short enough to be replicable
Externí odkaz:
https://doaj.org/article/8172248f55c54f299f90f1267c5b6b1a
Publikováno v:
Life, Vol 11, Iss 4, p 308 (2021)
Understanding the emergence of life from (primitive) abiotic components has arguably been one of the deepest and yet one of the most elusive scientific questions. Notwithstanding the lack of a clear definition for a living system, it is widely argued
Externí odkaz:
https://doaj.org/article/04af11acb2c34f9ab6fe9cf96ce339fa
Autor:
Sandeep Ameta, Manoj Kumar, Nayan Chakraborty, Yoshiya J. Matsubara, Prashanth S, Dhanush Gandavadi, Shashi Thutupalli
Robust localization of self-reproducing autocatalytic chemistries is a key step in the realization of heritable and evolvable chemical systems. While autocatalytic chemical reaction networks already possess attributes such as heritable self-reproduct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a66e83edc80e1929e56cf4f7f37f28a7
https://doi.org/10.1101/2022.11.01.514660
https://doi.org/10.1101/2022.11.01.514660
RNA diversification by a self-reproducing ribozyme revealed by deep sequencing and kinetic modelling
Autor:
Sandeep Ameta, Camille N Lambert, Alex Blokhuis, Cyrille Jeancolas, Thomas Alline, Andrew D. Griffiths, Sandeep Krishna, Mykhailo Vybornyi, Philippe Nghe, Yoshiya J. Matsubara
Publikováno v:
Chemical Communications, 57(61), 7517-7520. ROYAL SOC CHEMISTRY
Chemical Communications (Cambridge, England)
Chemical Communications (Cambridge, England)
We demonstrate that a recombinase ribozyme achieves multiple functions in the same reaction network: self-reproduction, iterative elongation and circularization of other RNAs, leading to synthesis of diverse products predicted by a kinetic model. Thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eefbf9689632270e6facb197771c13b
https://doi.org/10.1039/d1cc02290c
https://doi.org/10.1039/d1cc02290c
Autor:
Yoshiya J. Matsubara, Kunihiko Kaneko
Publikováno v:
Physical Review Letters. 121
Emergence and maintenance of polymers with complex sequences is a major question in the study of origins of life. To answer this, we studied a model polymerization reaction, where polymers are synthesized by stepwise ligation from two types of monome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be140430eeea859f405ded4315c1d202
https://doi.org/10.1103/physrevlett.121.118101
https://doi.org/10.1103/physrevlett.121.118101
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 6, p e1007094 (2019)
PLoS Computational Biology
PLoS Computational Biology
The emergence of replicases that can replicate themselves is a central issue in the origin of life. Recent experiments suggest that such replicases can be realized if an RNA polymerase ribozyme is divided into fragments short enough to be replicable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed8922d74f3bf02eb3b0e2976ef4cd10
https://doi.org/10.1371/journal.pcbi.1007094
https://doi.org/10.1371/journal.pcbi.1007094
Autor:
Yoshiya J. Matsubara, Kunihiko Kaneko
Publikováno v:
Physical Review E. 93
A biological system consists of a variety of polymers that are synthesized from monomers, by catalysis that exists only for some long polymers. It is important to elucidate the emergence and sustenance of such autocatalytic polymerization. We analyze
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b78ebf17dc27d4a4067f68814da2118
https://doi.org/10.1103/physreve.93.032503
https://doi.org/10.1103/physreve.93.032503
Autor:
Ameta, Sandeep1,2 (AUTHOR) sandeep.ameta@ashoka.edu.in, Kumar, Manoj1 (AUTHOR), Chakraborty, Nayan1 (AUTHOR), Matsubara, Yoshiya J.1 (AUTHOR), S, Prashanth1 (AUTHOR), Gandavadi, Dhanush1 (AUTHOR), Thutupalli, Shashi1,3 (AUTHOR) shashi@ncbs.res.in
Publikováno v:
Communications Chemistry. 5/8/2023, Vol. 6 Issue 1, p1-10. 10p.