Zobrazeno 1 - 10
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pro vyhledávání: '"Yoshitsugu Tobe"'
Autor:
Toru Goyagi, Yoshitsugu Tobe
Publikováno v:
British Journal of Medicine and Medical Research. 4:5238-5247
Aims: Dexmedetomidine, anα2adrenergicagonist, provides neuroprotection in various cerebral ischemia models and against anesthesia-related neurotoxicity. Dexmedetomidine also improves paraplegia induced by intrathecal morphine after short-term spinal
Publikováno v:
Acta Anaesthesiologica Scandinavica. 57:1245-1252
Background The current study was conducted to compare the effects of post-treatment with oestrogen on histological and neurological outcomes after short (7-day) and long (28-day) recovery periods in rats subjected to transient forebrain ischaemia. Me
Publikováno v:
Brain Research. 1461:96-101
Although selective beta-1 adrenoceptor antagonists are known to provide neuroprotective effects after brain ischemia, dose-response relationships of their neuroprotective effects have not been examined. The present study was conducted to evaluate whe
Publikováno v:
Brain Research. 1343:213-217
We have reported the neuroprotective effects of pre-treatment with beta-adrenoceptor antagonists on the cerebral infarction at 1 and 7 days after focal ischemia in rats. However, the protective effect of post-treatment with beta-adrenoceptor antagoni
Publikováno v:
Acta Anaesthesiologica Scandinavica. 54:377-382
BACKGROUND Dexmedetomidine and hypothermia are known to reduce neuronal injury following cerebral ischemia. We examined whether a combination of dexmedetomidine and hypothermia reduces brain injury after transient forebrain ischemia in rats to a grea
Publikováno v:
Acta Anaesthesiologica Scandinavica. 52:997-1002
BACKGROUND: We have previously reported that mivazerol, a alpha(2)-agonist, possibly provides neuroprotection against transient forebrain ischemia in rats. This study was designed to investigate the ability of mivazerol to attenuate ischemia-induced
Publikováno v:
Acta Anaesthesiologica Scandinavica. 49:1117-1123
Background: We examined whether mivazerol, an α2-agonist, had neuroprotective effects after transient forebrain ischemia in rats. Methods: Male Sprague-Dawley rats, anesthetized with halothane, were assigned to one of four groups (n = 10 each): cont
Autor:
Yoshitsugu Tobe, Toru Goyagi
Publikováno v:
Brain research. 1566
Dexmedetomidine, an α2 adrenoceptor agonist, provides neuroprotection against various cerebral ischemia models through its anti-apoptotic effects. Dexmedetomidine also improves paraplegia induced by intrathecal morphine after short-term spinal ische
Publikováno v:
British journal of anaesthesia. 109(3)
Although various reports have shown that β-antagonists provide neuroprotective effects after cerebral ischaemia, their effect on spatial memory after transient focal ischaemia is not known. We investigated the treatment of β1-antagonists on neurolo
Publikováno v:
Journal of neurosurgical anesthesiology. 23(2)
Background β-Adrenoreceptor antagonists provide neuroprotective effects after focal cerebral ischemia in experimental settings. This study was conducted to compare the neuroprotective effects of low-dose and high-dose of selective β1-adrenoreceptor