Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Yoshitomo Notsu"'
Autor:
Jubo Bhuiya, Yoshitomo Notsu, Hironori Kobayashi, Abu Zaffar Shibly, Abdullah Md. Sheikh, Ryota Okazaki, Kazuto Yamaguchi, Atsushi Nagai, Toru Nabika, Takafumi Abe, Masayuki Yamasaki, Minoru Isomura, Shozo Yano
Publikováno v:
Nutrients, Vol 15, Iss 3, p 759 (2023)
Recent evidence suggests that trimethylamine-N-oxide (TMAO), a metabolite of L-carnitine and choline, is linked to atherosclerosis and cardiovascular diseases. As TMAO content is very high in fish, we raised the following question: why do Japanese pe
Externí odkaz:
https://doaj.org/article/aa043cbf3a5c426f8e25c682af08b999
Autor:
Takanari Hattori, Yoshitomo Notsu, Misa Tanaka, Miki Matsui, Tetsuo Iida, Jun Watanabe, Yoshimitsu Osawa, Seiji Yamaguchi, Shozo Yano, Takeshi Taketani, Hironori Kobayashi
Publikováno v:
Children, Vol 9, Iss 5, p 694 (2022)
Flow injection analysis–tandem mass spectrometry (FIA-TMS) has been applied in a first-tier test of newborn screening (NBS). Although isovalerylcarnitine (i-C5), which is a diagnostic indicator of isovaleric acidemia (IVA), is isobaric with pivaloy
Externí odkaz:
https://doaj.org/article/d6852a94f40043b7ad2bbcf79dea0972
Autor:
Hiroshi Tobita, Hiromichi Sakai, Akane Yamaguchi, Yoshitomo Notsu, Masatoshi Kataoka, Tomotaka Yazaki, Toru Nabika, Shunji Ishihara, Hironori Kobayashi
Aim: Lysophosphatidic acid (LPA), which is produced by autotaxin (ATX) known as a marker of liver fibrosis, is a member of the group of lysophospholipids that function as extracellular mediators to activate specific G‐protein‐coupled receptors. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46307c18ba9040587cca84b50158d484
https://doi.org/10.21203/rs.3.rs-2755870/v1
https://doi.org/10.21203/rs.3.rs-2755870/v1
Autor:
Tsubasa Oguni, Shunji Tomatsu, Misa Tanaka, Kenji Orii, Toshiyuki Fukao, Jun Watanabe, Seiji Fukuda, Yoshitomo Notsu, Dung Chi Vu, Thi Bich Ngoc Can, Atsushi Nagai, Seiji Yamaguchi, Takeshi Taketani, Michael H. Gelb, Hironori Kobayashi
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 6, p 2025 (2020)
Mucopolysaccharidoses (MPSs) are rare lysosomal storage diseases caused by the accumulation of undegraded glycosaminoglycans in cells and tissues. The effectiveness of early intervention for MPS has been reported. Multiple-assay formats using tandem
Externí odkaz:
https://doaj.org/article/168d95bf9c244438b04a3d1ddcb9ebba
Autor:
Kazunari Ishitobi, Hitoshi Kotani, Yuichi Iida, Takahito Taniura, Yoshitomo Notsu, Yoshitsugu Tajima, Mamoru Harada
Publikováno v:
International immunopharmacology. 113
Myeloid-derived suppressor cells (MDSCs) and regulatory T cells (Tregs) are increased in cancer-bearing aged hosts. Arginase-I in MDSCs degrades L-arginine, an amino acid required for T cell activation and proliferation. In this study, we compared th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4f303c34bab30bc13fcc3bfcede6e9c
https://pubmed.ncbi.nlm.nih.gov/36461608
https://pubmed.ncbi.nlm.nih.gov/36461608
Publikováno v:
Cancer Science
Myeloid‐derived suppressor cells (MDSCs) play a crucial role in immunosuppression in tumor‐bearing hosts. MDSCs express arginase‐I and indoleamine 2,3‐dioxygenase; they suppress T‐cell function by reducing the levels of l‐arginine and l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b48689698a2a5213b1d928e41508f20f
http://europepmc.org/articles/PMC7484823
http://europepmc.org/articles/PMC7484823
Autor:
Zinat Mahal, Hiroyuki Matsuo, Hasan M. Zahid, Yoshitomo Notsu, Hiroki Ohara, Kenji Okamoto, Toru Nabika
Publikováno v:
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. 31(5)
In a previous study, a mushroom was shown to digest milk protein to a mixture of oligopeptides and free amino acids. The aim of this study was to examine effects of this mixture, i.e., mushroom-fermented milk, on blood pressure and stroke susceptibil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::481cd3766067b2984558350a8838605e
https://pubmed.ncbi.nlm.nih.gov/35255289
https://pubmed.ncbi.nlm.nih.gov/35255289
Publikováno v:
Atherosclerosis. 315:e134
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec13951da0181760b38345806e9e1eb3
https://doi.org/10.1016/j.atherosclerosis.2020.10.414
https://doi.org/10.1016/j.atherosclerosis.2020.10.414
Autor:
Hironori Kobayashi, Shunji Tomatsu, Takeshi Taketani, Kenji E. Orii, Atsushi Nagai, Yoshitomo Notsu, Toshiyuki Fukao, Jun Watanabe, Tsubasa Oguni, Misa Tanaka, Thi Bich Ngoc Can, Michael H. Gelb, Dung Chi Vu, Seiji Yamaguchi, Seiji Fukuda
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 6
International Journal of Molecular Sciences, Vol 21, Iss 6, p 2025 (2020)
Volume 21
Issue 6
International Journal of Molecular Sciences, Vol 21, Iss 6, p 2025 (2020)
Mucopolysaccharidoses (MPSs) are rare lysosomal storage diseases caused by the accumulation of undegraded glycosaminoglycans in cells and tissues. The effectiveness of early intervention for MPS has been reported. Multiple-assay formats using tandem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93a3c9498eec675bd056e1964f65f57a
https://doi.org/10.3390/ijms21062025
https://doi.org/10.3390/ijms21062025
Publikováno v:
Atherosclerosis. 239:61-66
Background: Asymmetric dimethylarginine (ADMA), which acts an endogenous inhibitor of nitric oxide synthase (NOS), is involved in the pathogenesis of cardiovascular disease. Arginine (Arg) may regulate vascular endothelial function, since Arg is the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eba46bf5775c1b85b6c7ec3380923cb
https://doi.org/10.1016/j.atherosclerosis.2014.12.030
https://doi.org/10.1016/j.atherosclerosis.2014.12.030