Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Yoshitomo Nagasawa"'
Autor:
Takahiro Kawajiri, Akihito Kijima, Atsuhiro Iimuro, Eisaku Ohashi, Katsuya Yamakawa, Kazushi Agura, Kengo Masuda, Kensuke Kouki, Koji Kasamatsu, Shuichi Yanagisawa, Sho Nakashima, Setsuya Shibahara, Takashi Toyota, Takafumi Higuchi, Takahiro Suto, Tadashi Oohara, Toshikatsu Maki, Naoto Sahara, Nobuaki Fukui, Hisayuki Wakamori, Hidaka Ikemoto, Hiroaki Murakami, Hiroyasu Ando, Masahiro Hosoya, Mizuki Sato, Yusuke Suzuki, Yuta Nakagawa, Yuto Unoh, Yoichi Hirano, Yoshitomo Nagasawa, Satoshi Goda, Takafumi Ohara, Takayuki Tsuritani
Publikováno v:
ACS Central Science, Vol 9, Iss 4, Pp 836-843 (2023)
Externí odkaz:
https://doaj.org/article/9f38b46b1b194cdaac85377b26776798
Autor:
Takahiro Kawajiri, Akihito Kijima, Atsuhiro Iimuro, Eisaku Ohashi, Katsuya Yamakawa, Kazushi Agura, Kengo Masuda, Kensuke Kouki, Koji Kasamatsu, Shuichi Yanagisawa, Sho Nakashima, Setsuya Shibahara, Takashi Toyota, Takafumi Higuchi, Takahiro Suto, Tadashi Oohara, Toshikatsu Maki, Naoto Sahara, Nobuaki Fukui, Hisayuki Wakamori, Hidaka Ikemoto, Hiroaki Murakami, Hiroyasu Ando, Masahiro Hosoya, Mizuki Sato, Yusuke Suzuki, Yuta Nakagawa, Yuto Unoh, Yoichi Hirano, Yoshitomo Nagasawa, Satoshi Goda, Takafumi Ohara, Takayuki Tsuritani
We describe the development of the practical manufacturing of Ensitrelvir, which was discovered as a SARS-CoV-2 antiviral candidate. Scalable synthetic methods of indazole, 1,2,4-triazole and 1,3,5-triazinone structures were established, and converge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6fe8efc31eb0dbe319232ced6f96b7a
https://doi.org/10.26434/chemrxiv-2022-wx3nl
https://doi.org/10.26434/chemrxiv-2022-wx3nl
Publikováno v:
Synthesis. 48:2845-2850
Styrenes reacted with sulfonamide in the presence of potassium carbonate and iodine in CHCl3 under visible light irradiation to produce the corresponding aziridines in moderate to good yields. A reaction mechanism to explain the formation of aziridin
Autor:
Yoshitomo Nagasawa, Tsuyoshi Miura, Norihiro Tada, Akichika Itoh, Eiji Yamaguchi, Akifumi Okada, Tomoaki Yamaguchi
Publikováno v:
RSC Advances. 6:42596-42599
This report describes a mild method for the direct transformation of β-oxoesters to the corresponding 2-hydroxymalonic esters, tartronic esters, using singlet oxygen produced by a catalytic amount of methylene blue and visible light irradiation usin
Publikováno v:
Organic Letters. 18:8-11
The intermolecular cyclopropanation of aromatic olefins with activated methylene compounds using iodine and visible light irradiation was described. This reaction proceeds under rare-metal-free conditions. Styrenes with various substituted groups (al
Publikováno v:
Chemistry, an Asian journal. 13(4)
Transition-metal-free synthesis of β-alkoxy monohydroperoxides via aerobic photooxidation using an acridinium photocatalyst was developed. This method enables the synthesis of some novel hydroperoxides. The peroxide source is molecular oxygen, which
Publikováno v:
Synlett. 26:412-415
We report the development of an aerobic photooxidation process with a continuous-flow microreactor that can form a slug flow region on the chip. The approach solved several problems raised by using batch systems.
Autor:
Tsuyoshi Miura, Norihiro Tada, Yoshitomo Nagasawa, Eiji Yamaguchi, Miyabi Taguchi, Akichika Itoh
Publikováno v:
Tetrahedron Letters. 57:230-232
We developed an aerobic photooxidative synthesis of peroxybenzoic acids from toluenes using anthraquinone-2-carboxylic acid (AQN-2-CO2H) as a photocatalyst. We also found a one-pot epoxidation reaction of alkenes using 4-tert-butylperoxybenzoic acid
Autor:
Norihiro Tada, Akichika Itoh, Tsuyoshi Miura, Toshiyuki Hotta, Yoshitomo Nagasawa, Yoko Matsusaki, Tomoya Nobuta
Publikováno v:
Tetrahedron Letters. 55:6543-6546
This Letter proposes a safe, mild, and environmentally benign method for the synthesis of benzimidazoles from aromatic aldehydes and diamines by aerobic photooxidation using irradiation with visible light, a catalytic amount of magnesium iodide, whic
Autor:
Sohei Furuhashi, Tsuyoshi Miura, Yuma Tachikawa, Lei Cui, Norihiro Tada, Yoshitomo Nagasawa, Akichika Itoh, Eiji Yamaguchi
Publikováno v:
RSC Advances. 5:9591-9593
We have developed a metal-free synthetic method for 3-nitroimidazo[1,2-a]pyridines from nitroalkenes and 2-aminopyridines using catalytic amounts of iodine and aqueous hydrogen peroxide as a terminal oxidant.