Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Yoshitomo Hamada"'
Autor:
Yoshitomo Hamada, Syota Takano, Yoshihiro Ayano, Masahiro Tokunaga, Takahiro Koashi, Syuhei Okamoto, Syoma Doi, Masahiko Ishida, Takashi Kawasaki, Masahiro Hamada, Noriyuki Nakajima, Akiko Saito
Publikováno v:
Molecules, Vol 20, Iss 10, Pp 18870-18885 (2015)
Proanthocyanidins, which are composed of oligomeric flavan-3-ol units, are contained in various foodstuffs (e.g., fruits, vegetables, and drinks) and are strongly biologically active compounds. We investigated which element of the proanthocyanidin st
Externí odkaz:
https://doaj.org/article/0bded6dcf306453cb954adc097f2c95f
Autor:
Kaori Miura, Hidekazu Ouchi, Akihiro Tai, Yoshitomo Hamada, Toshiro Noshita, Yuki Nishino, Ryoya Onishi
Publikováno v:
Phytochemistry Letters. 27:214-218
We herein describe the syntheses of 3,5-dimethoxy-4-{2-methoxy-4-[(1E)-3-oxoprop-1-en-1-yl]phenoxy}benzaldehyde (1) (the proposed structure for the naturally occurring protein tyrosine phosphatase 1B (PTP1B) inhibitor isolated from Acanthopanax senti
Autor:
Syuhei Okamoto, Masahiko Ishida, Akiko Saito, Takashi Kawasaki, Takahiro Koashi, Yoshitomo Hamada, Yoshihiro Ayano, Masahiro Hamada, Masahiro Tokunaga, Noriyuki Nakajima, Syoma Doi, Syota Takano
Publikováno v:
Molecules
Molecules, Vol 20, Iss 10, Pp 18870-18885 (2015)
Volume 20
Issue 10
Pages 18870-18885
Molecules, Vol 20, Iss 10, Pp 18870-18885 (2015)
Volume 20
Issue 10
Pages 18870-18885
Proanthocyanidins, which are composed of oligomeric flavan-3-ol units, are contained in various foodstuffs (e.g., fruits, vegetables, and drinks) and are strongly biologically active compounds. We investigated which element of the proanthocyanidin st
Publikováno v:
Natural product research. 31(18)
A series of 7-O-substituted hesperetins was evaluated for degranulation-inhibiting activity in rat basophil leukaemia cells. 7-O-Methyl and 7-O-ethyl hesperetin exhibited potent anti-degranulation activity compared with the original hesperetin.
Autor:
Yoshitomo Hamada, Teiko Yamada, Toshiro Noshita, Hidekazu Ouchi, Kohei Matsumoto, Akiko Saito, Hikaru Nishikawa
We describe the synthesis of 4,4′-oxyneolignan, the proposed structure for naturally occurring apteniol D. The diphenyl ether moiety in 4,4′-oxyneolignan was formed via classical Ullmann ether synthesis using excess copper powder in N,N-dimethyla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71e6933112f62c90deb599a493fdfc7f
Autor:
Yoshitomo Hamada, Kaoru Ikeda, Hikaru Nishikawa, Akiko Saito, Toshiro Noshita, Akihiro Tai, Teiko Yamada, Hidekazu Ouchi
Publikováno v:
Bioscience, biotechnology, and biochemistry. 79(11)
The synthesis of compounds with the structures proposed for the oxyneolignan apteniols B, C, and G is described. The diphenyl ether skeletons of the proposed apteniols were formed via Ullmann ether synthesis. In particular, the spectral data for the
Autor:
Masahiro Hamada, Yusuke Higashino, Noriyuki Nakajima, Ryuta Tanaka, Taichi Hojima, Takashi Kawasaki, Yoshitomo Hamada, Akiko Saito, Kazuki Mori, Mayu Izuno, Taisuke Okamoto, Yoshihiro Ayano
Publikováno v:
Natural Products Chemistry & Research. 3
Flavan-3-ol, which is primarily found in tea, is able to inhibit the proliferation of the human cancer cell line HeLa S3; in this study, we investigate the importance of the 2,3-cis structure in this inhibition. We synthesized six (−)-epicatechin a