Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Yoshitomi Nakane"'
Autor:
Takuya Iyoda, Yumi Nagamine, Yoshitomi Nakane, Yuya Tokita, Shougo Akari, Kazuki Otsuka, Motomichi Fujita, Keisuke Itagaki, You-Ichi Takizawa, Hiroaki Orita, Toshiyuki Owaki, Jyunichi Taira, Ryo Hayashi, Hiroaki Kodama, Fumio Fukai
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162525 (2016)
The acquisition of drug resistance mediated by the interaction of tumor cells with the extracellular matrix (ECM), commonly referred to as cell adhesion-mediated drug resistance (CAM-DR), has been observed not only in hematopoietic tumor cells but al
Externí odkaz:
https://doaj.org/article/7ca555ab31244a85abea6be1068b9b8c
Autor:
Yoshitomi Nakane1,2,3 yoshitomi.nakane@jt.com, Yusuke Kemmochi1, Naoto Ogawa1, Tomohiko Sasase1, Takeshi Ohta4, Yoshikazu Higami2, Fumio Fukai3
Publikováno v:
Journal of Toxicologic Pathology. 2020, Vol. 33 Issue 2, p121-129. 9p.
Autor:
Naoto Ogawa, Tomohiko Sasase, Fumio Fukai, Yoshitomi Nakane, Yoshikazu Higami, Yusuke Kemmochi, Takeshi Ohta
Publikováno v:
Journal of Toxicologic Pathology
Spontaneously Diabetic Torii (SDT) rats are a well-known animal model of non-obese type 2 diabetes mellitus. Although this animal model has been studied extensively over the last decade, the incidence rates of Leydig cell hyperplasia and tumors in th
Autor:
Yasuo Terasako, Takahisa Motomura, Genki Mori, Satoki Doi, Yoshitomi Nakane, Takuya Orita, Tomoko Iwanaga, Tatsuo Akaki, Shingo Obika, Ayumi Fujishima, Hiroshi Ueno, Yuki Bessho, Tsuyoshi Adachi, Maki Yamakawa, Yoshinori Hara, Katsutaka Yasue, Minoru Ubukata
Publikováno v:
Bioorganicmedicinal chemistry. 52
Pyruvate dehydrogenase kinases (PDHKs) are fascinating drug targets for numerous diseases, including diabetes and cancers. In this report, we describe the result of our structure-based drug design from tricyclic lead compounds that led to the discove
Autor:
You-ichi Takizawa, Keisuke Itagaki, Toshiyuki Owaki, Shougo Akari, Ryo Hayashi, Hiroaki Kodama, Takuya Iyoda, Fumio Fukai, Hiroaki Orita, Jyunichi Taira, Yuya Tokita, Yumi Nagamine, Yoshitomi Nakane, Motomichi Fujita, Kazuki Otsuka
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 9, p e0162525 (2016)
PLoS ONE, Vol 11, Iss 9, p e0162525 (2016)
The acquisition of drug resistance mediated by the interaction of tumor cells with the extracellular matrix (ECM), commonly referred to as cell adhesion-mediated drug resistance (CAM-DR), has been observed not only in hematopoietic tumor cells but al