Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Yoshito Nishihata"'
Autor:
Takahiro Kitazawa, Daisuke Kishi, Satomi Shimizu, Yoshito Nishihata, Emi Okazaki, Masahiro Mochizuki, Takumi Ohishi, Yuri Kidokoro, Takashi Kamata
Publikováno v:
The Journal of Toxicological Sciences. 34:603-610
Effects of repeated administration of phenobarbital (PB) on blood coagulation-related parameters were examined in non-pregnant, pregnant and lactating rats, and also in pups born to PB-treated lactating dams. PB was orally administered at a dose leve
Autor:
Yoshito Nishihata, Yoshinaka Urasoko, Takashi Kamata, Satomi Shimizu, Hiroshi Edamoto, Masahiro Mochizuki, Takahiro Kitazawa, Takumi Ohishi, Daichi Nakamura, Kazuhiko Umeshita
Publikováno v:
The Journal of toxicological sciences. 34(2)
Carbon tetrachloride (CCl4) is well known to induce hepatotoxicity after being metabolized to trichloromethyl free radical ((.)CCl3) by CYP2E1. In the present study, the hepatotoxicity induced by a single oral dose (2,000 mg/kg) of CCl4 was compared