Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Yoshito Nagashima"'
Autor:
Yoshito Nagashima, Masamichi Hirose, Yasuyuki Furukawa, Shigetoshi Chiba, Manoj Lakhe, Yuji Hoyano
Publikováno v:
Journal of Cardiovascular Pharmacology. 31:18-24
Prolongation of the functional recovery of the sinoatrial (SA) nodal pacemaker activity after overdrive, "overdrive suppression," is determined by intrinsic pacemaker activity, pacemaker site, and SA conduction. We investigated the effects of E-4031,
Publikováno v:
Fundamental & Clinical Pharmacology. 11:331-338
We investigated the effects of terikalant, which blocks inward rectifier K+ current, on the sinus rate, atrial and ventricular contractile force in the isolated, blood-perfused right atrial and left ventricular preparations of dogs, and the effects o
Publikováno v:
Japanese Journal of Electrocardiology. 16:324-331
生体内心臓において洞調律を選択的に調節する心臓内副交感神経刺激 (SAP刺激) によるアセチルコリン依存性Kチャネル活性化と遅延整流K電流 (IK) 阻害薬, E-4031によるIK遮断の洞房結節の歩
Publikováno v:
Journal of anesthesia. 14(1)
Autor:
Manoj Lakhe, Masamichi Hirose, Yasuyuki Furukawa, Takanori Yonezawa, Yoshito Nagashima, Yusuke Miyashita, Shigetoshi Chiba
Publikováno v:
Japanese journal of pharmacology. 76(4)
To investigate whether a Ca2+ sensitizer increases sinus rate, we studied the effects of racemic thiadiazinone, EMD 53998 (a Ca2+ sensitizer with phosphodiesterase inhibitory action) and its (+)-enantiomer EMD 57033 (a relatively pure Ca2+ sensitizer
Autor:
Yoshito Nagashima, Shigetoshi Chiba, Yusuke Miyashita, Masamichi Hirose, Yasuyuki Furukawa, Manoj Lakhe
Publikováno v:
European journal of pharmacology. 338(1)
While pituitary adenylate cyclase-activating polypeptide (PACAP) has been identified radioimmunologically in the rat heart, the physiological role of PACAP has not been elucidated in the regulation of the atrioventricular conduction in the heart. We,
Autor:
Yasuyuki Furukawa, Masamichi Hirose, Yuji Hoyano, Kyouhei Yamazaki, Shigetoshi Chiba, Yoshito Nagashima
Publikováno v:
Journal of cardiovascular pharmacology. 29(2)
Pituitary adenylate cyclase-activating polypeptide (PACAP) receptors exist, but the physiologic role of PACAP is unclear in the heart in situ. We investigated effects of PACAP-38 on sinus rate and on the negative chronotropic response to acetylcholin
Autor:
Takanori Yonezawa, Masamichi Hirose, Yasuyuki Furukawa, Yoshito Nagashima, Shigetoshi Chiba, Manoj Lakhe
Publikováno v:
European journal of pharmacology. 315(3)
A pituitary adenylate cyclase-activating polypeptide (PACAP) activates PACAP and vasoactive intestinal peptide (VIP) receptors. We investigated the effects of PACAP-38 on the sinus rate and atrial contractile force in isolated, blood-perfused dog hea
Autor:
Yasuyuki Furukawa, Yoshito Nagashima, Masamichi Hirose, Shigetoshi Chiba, Manoj Lakhe, Takanori Yonezawa
Publikováno v:
Japanese journal of pharmacology. 71(4)
We investigated the effects of U-92032 ((7-((bis-4-fluorophenyl)methyl)-1-piperazinyl)-2-2(2-hydroxyethylamino)-4-(1-methylethyl)-2,4,6-cycloheptatrien-1-one), a novel T-type Ca2+ channel blocker, on sinus rate and atrial contractile force in the iso
Publikováno v:
Journal of Anesthesia. 9
Laparoscopic cholecystectomy is rapidly gaining popularity with surgeons and patients, but as the popularity of this technique increases and the selection of patients widens to older and sicker people, careful considerations in anesthetic management