Zobrazeno 1 - 10
of 166
pro vyhledávání: '"Yoshito Abe"'
Autor:
Chinatsu Shinozaki, Keita Kohno, Mitsunori Shiroishi, Daisuke Takahashi, Yu Yoshikawa, Yoshito Abe, Kenji Hamase, Makoto Nakakido, Kohei Tsumoto, Kazuhide Inoue, Makoto Tsuda, Tadashi Ueda
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract We have recently developed a mouse monoclonal antibody (12–10H) binding to the head domain region in rat P2X4 receptor (rP2X4R, which is crucial for the pathogenesis of neuropathic pain) expressed on the cell with the highest binding affin
Externí odkaz:
https://doaj.org/article/56486021f0394e62b51df59f5de03618
Autor:
Afsal Kareekunnan, Tatsufumi Agari, Takeshi Kudo, Shunsuke Niwa, Yoshito Abe, Takeshi Maruyama, Hiroshi Mizuta, Manoharan Muruganathan
Publikováno v:
AIP Advances, Vol 12, Iss 9, Pp 095209-095209-4 (2022)
Graphene is widely used in various real-life applications due to its high sensitivity to the change in the carrier concentration. Here, we demonstrate that graphene can be used for implementing a reliable lightning detection network as it shows excel
Externí odkaz:
https://doaj.org/article/daf303ce6d92465db709782023afe605
Autor:
Tanapati Phakham, Christine Joy I. Bulaon, Narach Khorattanakulchai, Balamurugan Shanmugaraj, Supranee Buranapraditkun, Chatikorn Boonkrai, Sarintip Sooksai, Nattiya Hirankarn, Yoshito Abe, Richard Strasser, Kaewta Rattanapisit, Waranyoo Phoolcharoen
Publikováno v:
Frontiers in Plant Science, Vol 12 (2021)
The striking innovation and clinical success of immune checkpoint inhibitors (ICIs) have undoubtedly contributed to a breakthrough in cancer immunotherapy. Generally, ICIs produced in mammalian cells requires high investment, production costs, and in
Externí odkaz:
https://doaj.org/article/4f30ab7d642e457f8e5f8b886945bb9e
Autor:
Wanuttha Boonyayothin, Sirorut Sinnung, Balamurugan Shanmugaraj, Yoshito Abe, Richard Strasser, Prasit Pavasant, Waranyoo Phoolcharoen
Publikováno v:
Frontiers in Plant Science, Vol 12 (2021)
Denosumab, an anti-receptor activator of nuclear factor-kappa B ligand antibody (anti-RANKL), is a fully human monoclonal antibody (mAb) available for the treatment of osteoporosis. In the present study, an anti-RANKL mAb was transiently expressed us
Externí odkaz:
https://doaj.org/article/a88a5bc7054246f9b68f294281f57a34
Autor:
Junichiro Futami, Haruna Fujiyama, Rie Kinoshita, Hidenori Nonomura, Tomoko Honjo, Hiroko Tada, Hirokazu Matsushita, Yoshito Abe, Kazuhiro Kakimi
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e113295 (2014)
Preventing protein aggregation is a major goal of biotechnology. Since protein aggregates are mainly comprised of unfolded proteins, protecting against denaturation is likely to assist solubility in an aqueous medium. Contrary to this concept, we fou
Externí odkaz:
https://doaj.org/article/b8f4c1796482454d8992bfa2af594769
Publikováno v:
The Protein Journal. 41:71-78
Protein structures fluctuate in solution; therefore, proteins have multiple stable structures that are slightly different from each other. In this study, we determined the crystal structure of hen egg lysozyme refolded after denaturation at acidic pH
Publikováno v:
International Journal of Biological Macromolecules. 166:342-351
Glycosylation is one of the major post-translational modifications in eukaryotic cells and has been reported to affect the amyloid fibril formation in several amyloidogenic proteins and peptides. In this study, we expressed a Vλ6 light chain mutant,
Publikováno v:
FEBS Letters. 595:341-350
In Escherichia coli, DNA replication is restarted following DNA repair by the PriA-dependent pathway, in which the binding and dissociation of proteins such as PriA, PriB, and DnaT on ssDNA lead to the formation of a protein-DNA complex for recruitin
Publikováno v:
The Journal of Biochemistry. 169:491-496
P2X4 receptor is known to be involved in neuropathic pain. In order to detect the expression of P2X4 receptor on microglia at the time of onset of neuropathic pain, one approach consists on the preparation of the monoclonal antibodies with both selec
Autor:
Daisuke Takahashi, Eri Matsunaga, Tomohiro Yamashita, Jose M.M. Caaveiro, Yoshito Abe, Tadashi Ueda
Publikováno v:
Biochemical and biophysical research communications. 596
AL amyloidosis is a life-threatening disease characterized by the deposition of amyloidogenic immunoglobulin light chain secreted from clonal plasma cells. Here we established an in-vitro screening system of amyloid inhibition of a variable domain in