Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Yoshiteru Sasaki"'
Autor:
Katsuya Endo, Tomonori Satoh, Yuki Yoshino, Shiho Kondo, Yoko Kawakami, Tomofumi Katayama, Yoshiteru Sasaki, Atsuko Takasu, Takayuki Kogure, Morihisa Hirota, Takayoshi Meguro, Kennichi Satoh
Publikováno v:
Inflammatory Intestinal Diseases, Vol 6, Iss 4, Pp 218-224 (2021)
Introduction: Predictive biomarkers for the therapeutic outcome of induction therapy with systemic corticosteroid for active ulcerative colitis (UC) have not been established. This study aimed to investigate whether neutrophil-to-lymphocyte ratio (NL
Externí odkaz:
https://doaj.org/article/0a0124e7a6ef4c5c93cd987316a6ee45
Autor:
Katsuhiro Sasaki, Ai Himeno, Tomoko Nakagawa, Yoshiteru Sasaki, Hiroshi Kiyonari, Kazuhiro Iwai
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Many forms of autoimmune disorder involve abnormal T cell functions, but how this versatility is achieved is not fully clear. Here the authors show that Sharpin-deficient Treg cells induce the death of local keratinocytes via multiple programmed cell
Externí odkaz:
https://doaj.org/article/716b05e17f3c43fa880e9ce7ddca92ca
Autor:
Katsuya Endo, Takehito Ito, Jun Nomura, Keigo Murakami, Shiho Kondo, Tomonori Satoh, Daisuke Fukushi, Yuki Yoshino, Yoshiteru Sasaki, Atsuko Takasu, Takayuki Kogure, Morihisa Hirota, Takayoshi Meguro, Kazuhiro Murakami, Junichi Kameoka, Kennichi Satoh
Publikováno v:
Case Reports in Gastrointestinal Medicine, Vol 2021 (2021)
Multiple myeloma is a type of plasma cell neoplasm that produces monoclonal immunoglobulin. Multiple myeloma is known to cause immunoglobulin light-chain (AL) amyloidosis, which frequently involves the kidney and heart. Bone pain or fractures caused
Externí odkaz:
https://doaj.org/article/6f02059977ac476e8b36d6612adb6b66
Autor:
Hiroaki Fujita, Akira Tokunaga, Satoshi Shimizu, Amanda L. Whiting, Francisco Aguilar-Alonso, Kenji Takagi, Erik Walinda, Yoshiteru Sasaki, Taketo Shimokawa, Tsunehiro Mizushima, Izuru Ohki, Mariko Ariyoshi, Hidehito Tochio, Federico Bernal, Masahiro Shirakawa, Kazuhiro Iwai
Publikováno v:
Cell Reports, Vol 23, Iss 4, Pp 1192-1204 (2018)
Summary: The linear ubiquitin chain assembly complex (LUBAC) participates in inflammatory and oncogenic signaling by conjugating linear ubiquitin chains to target proteins. LUBAC consists of the catalytic HOIP subunit and two accessory subunits, HOIL
Externí odkaz:
https://doaj.org/article/7c862e83f5e5418699f786a096c66df4
Autor:
Özlem Akilli Öztürk, Hubert Pakula, Jolanta Chmielowiec, Jingjing Qi, Simone Stein, Linxiang Lan, Yoshiteru Sasaki, Klaus Rajewsky, Walter Birchmeier
Publikováno v:
Cell Reports, Vol 13, Iss 3, Pp 561-572 (2015)
Gab1 is a scaffold protein that acts downstream of receptor tyrosine kinases. Here, we produced conditional Gab1 mutant mice (by K14- and Krox20-cre) and show that Gab1 mediates crucial signals in the control of both the hair cycle and the self-renew
Externí odkaz:
https://doaj.org/article/f2b5ea800f4f49809bc188cdff8eafcd
An Oncogenic Role for Alternative NF-κB Signaling in DLBCL Revealed upon Deregulated BCL6 Expression
Autor:
Baochun Zhang, Dinis Pedro Calado, Zhe Wang, Sebastian Fröhler, Karl Köchert, Yu Qian, Sergei B. Koralov, Marc Schmidt-Supprian, Yoshiteru Sasaki, Christine Unitt, Scott Rodig, Wei Chen, Riccardo Dalla-Favera, Frederick W. Alt, Laura Pasqualucci, Klaus Rajewsky
Publikováno v:
Cell Reports, Vol 11, Iss 5, Pp 715-726 (2015)
Diffuse large B cell lymphoma (DLBCL) is a complex disease comprising diverse subtypes and genetic profiles. Possibly because of the prevalence of genetic alterations activating canonical NF-κB activity, a role for oncogenic lesions that activate th
Externí odkaz:
https://doaj.org/article/0adde42dafeb4648b4fdce0be395be80
Autor:
Chang Yang, Kathleen McCoy, Jennifer L Davis, Marc Schmidt-Supprian, Yoshiteru Sasaki, Roberta Faccio, Deborah Veis Novack
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e15383 (2010)
Maintenance of healthy bone requires the balanced activities of osteoclasts (OCs), which resorb bone, and osteoblasts, which build bone. Disproportionate action of OCs is responsible for the bone loss associated with postmenopausal osteoporosis and r
Externí odkaz:
https://doaj.org/article/9cd15979dfd046b4b56175dc790f7dab
Autor:
Kazuhiro Murakami, Takayoshi Meguro, Yoshiteru Sasaki, Akinobu Koiwai, Morihisa Hirota, Takayuki Kogure, Atsuko Takasu, Keita Kawamura, Katsuya Endo, Keigo Murakami, Ken Nihei, Kennichi Satoh
Publikováno v:
Internal Medicine
Acute pancreatitis is an extraintestinal manifestation of inflammatory bowel disease. There have been few reports describing acute pancreatitis preceding a diagnosis of inflammatory bowel disease. We herein report a rare case of a 16-year-old boy wit
Autor:
Michael Haap, Lothar Kanz, Alexander R. Fuchs, Martin Müller, Hans-Georg Kopp, Stefan Wirths, David J. Müller, Yoshiteru Sasaki, Marc Sturm, Andreas Kirschniak, Melanie Märklin, Jonas S. Heitmann
Publikováno v:
Journal of Leukocyte Biology. 105:531-538
Chronic lymphocytic leukemia (CLL) can be defined as a clonal expansion of B cells with stereotypic BCRs. Somatic hypermutation of the BCR heavy chains (IGVH) defines a subgroup of patients with a better prognosis. In up to 10% of CLL cases, a transf
Autor:
Jun Nomura, Yoshiteru Sasaki, Morihisa Hirota, Kazuhiro Murakami, Junichi Kameoka, Tomonori Satoh, Yuki Yoshino, Katsuya Endo, Atsuko Takasu, Shiho Kondo, Keigo Murakami, Daisuke Fukushi, Takayoshi Meguro, Takehito Ito, Kennichi Satoh, Takayuki Kogure
Publikováno v:
Case Reports in Gastrointestinal Medicine, Vol 2021 (2021)
Case Reports in Gastrointestinal Medicine
Case Reports in Gastrointestinal Medicine
Multiple myeloma is a type of plasma cell neoplasm that produces monoclonal immunoglobulin. Multiple myeloma is known to cause immunoglobulin light-chain (AL) amyloidosis, which frequently involves the kidney and heart. Bone pain or fractures caused