Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Yoshiteru Miyauchi"'
Autor:
Yuiko Sato, Yoshiteru Miyauchi, Shigeyuki Yoshida, Mayu Morita, Tami Kobayashi, Hiroya Kanagawa, Eri Katsuyama, Atsuhiro Fujie, Wu Hao, Toshimi Tando, Ryuichi Watanabe, Kana Miyamoto, Hideo Morioka, Morio Matsumoto, Yoshiaki Toyama, Takeshi Miyamoto
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e111845 (2014)
Although both an active form of the vitamin D metabolite, 1,25(OH)2D3, and the vitamin D analogue, ED71 have been used to treat osteoporosis, anti-bone resorbing activity is reportedly seen only in ED71- but not in 1,25(OH)2D3 -treated patients. In a
Externí odkaz:
https://doaj.org/article/0a3fea07b10e4bb7810718a5c7291c3a
Autor:
Hirono Iriuchishima, Keiyo Takubo, Yoshitaka Miyakawa, Ayako Nakamura-Ishizu, Yoshiteru Miyauchi, Nobuyuki Fujita, Kana Miyamoto, Takeshi Miyamoto, Eiji Ikeda, Masahiro Kizaki, Yoshihisa Nojima, Toshio Suda
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e30557 (2012)
The interaction with bone marrow (BM) plays a crucial role in pathophysiological features of multiple myeloma (MM), including cell proliferation, chemoresistance, and bone lesion progression. To characterize the MM-BM interactions, we utilized an in
Externí odkaz:
https://doaj.org/article/136cbdb31e1b4d92a247dae635faa08a
Autor:
Takeshi Miyamoto, Randall S. Johnson, Pierre Chambon, Hiroya Kanagawa, Yoshiteru Miyauchi, Toshimi Tando, Yuiko Sato, Atsuhiro Fujie, Kana Miyamoto, Hideo Morioka, Tami Kobayashi, Shigeaki Kato, Yoshiaki Toyama, Morio Matsumoto, Wu Hao, Tomoaki Mori, Shigeyuki Yoshida, Eri Katsuyama
Publikováno v:
Proceedings of the National Academy of Sciences. 110:16568-16573
In women, estrogen deficiency after menopause frequently accelerates osteoclastic bone resorption, leading to osteoporosis, the most common skeletal disorder. However, mechanisms underlying osteoporosis resulting from estrogen deficiency remain large
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0922180bf541b8a7623a6afa82ed868
https://doi.org/10.1073/pnas.1308755110
https://doi.org/10.1073/pnas.1308755110
Autor:
Ryotaro Iwasaki, Yoshiteru Miyauchi, Hiroko Hoshi, Hiroya Miyamoto, Tomoaki Mori, Yuiko Sato, Takeshi Miyamoto, Wu Hao, Tami Kobayashi, Eri Katsuyama, Hiroya Kanagawa, Yoshiaki Toyama, Shigeyuki Yoshida, Kana Miyamoto, Hideo Morioka, Morio Matsumoto, Atsuhiro Fujie
Publikováno v:
Journal of Biological Chemistry. 287:32479-32484
Macrophage lineage cells such as osteoclasts and foreign body giant cells (FBGCs) form multinuclear cells by cell-cell fusion of mononuclear cells. Recently, we reported that two seven-transmembrane molecules, osteoclast stimulatory transmembrane pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b267b4159e8e1a78dd1b477f1dd2895
https://doi.org/10.1074/jbc.m112.358226
https://doi.org/10.1074/jbc.m112.358226
Autor:
Yoshiaki Toyama, Yoshiteru Miyauchi, Hiroya Miyamoto, Tami Kobayashi, Haruhiko Akiyama, Shigeyuki Yoshida, Hideo Morioka, Tomoaki Mori, Yuiko Sato, Wu Hao, Morio Matsumoto, Eri Katsuyama, Kana Miyamoto, Takeshi Miyamoto, Hiroya Kanagawa, Atsuhiro Fujie, Hiroko Hoshi
Publikováno v:
Journal of Biological Chemistry. 287:28508-28517
Bone resorption, which is regulated by osteoclasts, is excessively activated in bone destructive diseases such as osteoporosis. Thus, controlling osteoclasts would be an effective strategy to prevent pathological bone loss. Although several transcrip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cce07d72882d23a9943b2e57280f03d7
https://doi.org/10.1074/jbc.m112.356634
https://doi.org/10.1074/jbc.m112.356634
Autor:
Naobumi Hosogane, Morio Matsumoto, Guanyu Cui, Kazuhiro Chiba, Yoshiaki Toyama, Masaya Nakamura, Yoshiteru Miyauchi, Takashi Tsuji, Kota Watanabe, Takeshi Miyamoto, Ken Ishii
Publikováno v:
Journal of Orthopaedic Science. 16:785-790
Lumbar spinal canal stenosis (LSCS) is one of the most common spinal disorders in the elderly, and ligamentum flavum (LF) hypertrophy is an important cause of LSCS. Matrix metalloproteinase 13 (MMP13) can degrade fibrillar collagens and elastic micro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7571d16d0fdd779e40483482696aa863
https://doi.org/10.1007/s00776-011-0135-2
https://doi.org/10.1007/s00776-011-0135-2
Autor:
Yoshiaki Toyama, Ken Ninomiya, Toshio Suda, Yoshiteru Miyauchi, Koh Hei Sonoda, Ryotaro Iwasaki, Yuiko Sato, Kensuke Egashira, Hiroko Hoshi, Hiroya Miyamoto, Takeshi Miyamoto, Shigeyuki Yoshida, Kana Miyamoto, Kazuhiro Chiba, Hideo Morioka
Publikováno v:
Biochemical and Biophysical Research Communications. 383:373-377
Monocyte chemoattractant protein-1 (MCP-1) is a chemokine that plays a critical role in the recruitment and activation of leukocytes. Here, we describe that multinuclear osteoclast formation was significantly inhibited in cells derived from MCP-1-def
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2abbde574ea0d4e944b1182196a47e02
https://doi.org/10.1016/j.bbrc.2009.04.020
https://doi.org/10.1016/j.bbrc.2009.04.020
Autor:
Hironori Kaneko, Tadatsugu Taniguchi, Yoshiaki Toyama, Takeshi Miyamoto, Yoshiteru Miyauchi, Ayako Shiraishi, Akio Tanaka, Toshio Suda, Kenichiro Matsuzaki, Sadaoki Sakai, Mitsuru Furukawa, Keiji Saito, Hironari Takaishi
Publikováno v:
Journal of Bone and Mineral Metabolism. 27:643-652
1-Alpha, 25-dihydroxy vitamin D(3) (1alpha,25(OH)(2)D(3)), an active form of vitamin D(3), plays a critical role in calcium and bone metabolism. Although 1alpha,25(OH)(2)D(3) has been used for osteoporosis therapy, the direct role of 1alpha,25(OH)(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f4339764dc9001f99a77e9cc8d8b470
https://doi.org/10.1007/s00774-009-0084-4
https://doi.org/10.1007/s00774-009-0084-4
Autor:
Takeshi Miyamoto, Yoshiaki Toyama, Naoto Kosaki, Keisuke Horiuchi, Jiro Takito, Akihiro Hakozaki, Mitsuru Furukawa, Kenichiro Matsuzaki, Hironari Takaishi, Yoshiteru Miyauchi, Hideo Morioka, Hironori Kaneko, Carl P. Blobel
Publikováno v:
Scopus-Elsevier
CSF-1 is a hemopoietic growth factor, which plays an essential role in macrophage and osteoclast development. Alternative splice variants of CSF-1 are synthesized as soluble or membrane-anchored molecules, although membrane CSF-1 (mCSF-1) can be clea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbc94387468112fe6fbe2490269d417b
https://doi.org/10.4049/jimmunol.179.10.6715
https://doi.org/10.4049/jimmunol.179.10.6715
Autor:
Hiroki Kondou, Toshimi Michigami, Masayo Yamagata, Keiichi Ozono, Yoshiteru Miyauchi, Yuta Hashimoto
Publikováno v:
Journal of the American Society of Nephrology. 16:2338-2345
Megalin is a multifunctional endocytic receptor that is expressed in renal proximal tubules and plays critical roles in the renal uptake of various proteins. It was hypothesized that megalin-dependent endocytosis might play a role in renal phosphate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca2ad072c185781ef818f0fe15e45982
https://doi.org/10.1681/asn.2004070599
https://doi.org/10.1681/asn.2004070599