Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Yoshitaka Tayama"'
Autor:
Yoshitaka Tayama, Kazumi Sugihara, Seigo Sanoh, Katsushi Miyake, Shigeyuki Kitamura, Shigeru Ohta
Publikováno v:
Journal of Pharmaceutical Health Care and Sciences, Vol 8, Iss 1, Pp 1-11 (2022)
Abstract Background Allopurinol is used to treat hyperuricemia and gout. It is metabolized to oxypurinol by xanthine oxidase (XO), and aldehyde oxidase (AO). Allopurinol and oxypurinol are potent XO inhibitors that reduce the plasma uric acid levels.
Externí odkaz:
https://doaj.org/article/ce6e3b2e3f434a01ad80302182c4c6a3
Autor:
Masako Yasuhara, Yoshitaka Tayama, Takehiro Kashiwagi, Akihiro Sawa, Kenji Kihira, Katsushi Miyake
Publikováno v:
Journal of King Saud University: Science, Vol 28, Iss 2, Pp 198-202 (2016)
Bakumondo-to is a traditional herbal medicine. It has been widely used for the treatment of chronic airway diseases. Recently, it was reported that several herbal medicines affected cytochrome P450 (CYP). However, there is little information about th
Externí odkaz:
https://doaj.org/article/3a9d37c0a5c54df8bdfaa0abf36f7976
Autor:
Seigo Sanoh, Yoshitaka Tayama, Hiromitsu Watanabe, Ryo Shimizu, Kazumi Sugihara, Shigeru Ohta, Masumi Motonaga, Yaichiro Kotake, Shigeyuki Kitamura
Publikováno v:
BPB Reports. 4:148-154
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be8a429c475a35aedf69649fba9a8601
https://doi.org/10.1248/bpbreports.4.5_148
https://doi.org/10.1248/bpbreports.4.5_148
Autor:
Ryuto Maeda, Hidetomo Kobayashi, Mami Higashidani, Tetsuaki Matsuhisa, Akihiro Sawa, Katsushi Miyake, Yoshitaka Tayama, Kouji Kimura, Hiroyuki Itoh, Taichi Okano, Soshi Seike, Hiroyasu Yamanaka
Publikováno v:
Access Microbiology. 4
Introduction. Methicillin-resistant Staphylococcus aureus (MRSA) is one of the major pathogens of nosocomial infections throughout the world. In the medical field, it is extremely important to this pathogen’s trends when considering infection contr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::363f00db5c78c7f514779ad03300fb03
https://doi.org/10.1099/acmi.0.000319
https://doi.org/10.1099/acmi.0.000319
Autor:
Ryuto, Maeda, Hidetomo, Kobayashi, Mami, Higashidani, Tetsuaki, Matsuhisa, Akihiro, Sawa, Katsushi, Miyake, Yoshitaka, Tayama, Kouji, Kimura, Hiroyuki, Itoh, Taichi, Okano, Soshi, Seike, Hiroyasu, Yamanaka
Publikováno v:
Access microbiology. 4(2)
Methicillin-resistantWe hypothesized that clarifying the characteristics of clinically isolated MRSA would contribute to infection control and proper use of antimicrobial agents against MRSA.The purpose of this study is to elucidate the genetic and b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6ec88a9b603786e67010793588e2e4aa
https://pubmed.ncbi.nlm.nih.gov/35355871
https://pubmed.ncbi.nlm.nih.gov/35355871
Autor:
Kazumi Sugihara, Yoshitaka Tayama, Yaichiro Kotake, Mineko Terao, Katsuhiro Okuda, Shigeru Ohta, Naoki Takaoka, Seigo Sanoh, Shigeyuki Kitamura, Go Sugahara, Chise Tateno, Enrico Garattini, Ami Yanagi, Mami Kurosaki, Yuji Ishida
Publikováno v:
Biochemical Pharmacology. 154:28-38
As aldehyde oxidase (AOX) plays an emerging role in drug metabolism, understanding its significance for drug–drug interactions (DDI) is important. Therefore, we tested 10 compounds for species-specific and substrate-dependent differences in the inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7314a9da94e03a427ea92dece402b9b
https://doi.org/10.1016/j.bcp.2018.04.017
https://doi.org/10.1016/j.bcp.2018.04.017
Autor:
Shigeru Ohta, Kazumi Sugihara, Naoto Uramaru, Shigeyuki Kitamura, Yoshitaka Tayama, Yoko Watanabe, Chiaki Tanoue
Publikováno v:
Drug Metabolism Letters. 10:278-285
Background: Zaleplon (ZAL) is a sedative-hypnotic agent, which is mainly metabolized to inactive 5-oxidized zaleplon (5-oxo-ZAL) and N-des-ethylated ZAL (des-ethyl-ZAL) in mice and humans. The former reaction is considered to be catalyzed by aldehyde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa7564eec4a3c446553b6542c544e6f1
https://doi.org/10.2174/1872312810666161227145358
https://doi.org/10.2174/1872312810666161227145358
Autor:
Katsushi Miyake, Shigeyuki Kitamura, Shizuko Maeda, Toyohisa Tsukamoto, Eiko Takahashi, Yoshitaka Tayama, Kazumi Sugihara
Publikováno v:
Fundamental Toxicological Sciences. 3:177-183
In hospitals and pharmacies, many kinds of pharmaceutical tablets are frequently crushed to powder in order to facilitate administration. However, there is concern about the influence of this process on the health of pharmacy workers. In this study,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89377deb14900ab58aad648b43ebadec
https://doi.org/10.2131/fts.3.177
https://doi.org/10.2131/fts.3.177
Publikováno v:
Drug Metabolism and Pharmacokinetics. 30:52-63
Aldehyde oxidase contributes to drug metabolism and pharmacokinetics (PK), and a few clinical studies were discontinued because of aldehyde oxidase metabolism. Its AOX1, AOX3, AOX3L1, and AOX4 isoforms are expressed in mammals, and species difference
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b93b339a9f34b6b840fbe05ad8bd8cf
https://doi.org/10.1016/j.dmpk.2014.10.009
https://doi.org/10.1016/j.dmpk.2014.10.009
Autor:
Yoko Watanabe, Chiaki Tanoue, Yoshitaka Tayama, Kazumi Sugihara, Naoto Uramaru, Shigeyuki Kitamura, Shigeru Ohta, Toru Horie
Publikováno v:
Xenobiotica. 43:956-962
1. Human chimeric mice (h-PXB mice) having humanized liver, constructed by transplantation of human hepatocytes, were evaluated as an experimental model for predicting human drug metabolism. Metabolism of zaleplon in h-PXB mice was compared with that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fd08ec8b334d9170b59c368d833e8ae
https://doi.org/10.3109/00498254.2013.788232
https://doi.org/10.3109/00498254.2013.788232