Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Yoshitaka OHNO"'
Autor:
Tatsuro Egawa, Yoshitaka Ohno, Shingo Yokoyama, Ayumi Goto, Rika Ito, Tatsuya Hayashi, Katsumasa Goto
Publikováno v:
Journal of Physical Fitness and Sports Medicine, Vol 7, Iss 4, Pp 229-238 (2018)
The accumulation of advanced glycation end products (AGEs) in the body causes the pathogenesis of aging-related diseases by inhibiting the normal properties and functions of proteins and the modulation of cellular signal transduction. Glycation stres
Externí odkaz:
https://doaj.org/article/a6647d6600a84c449b0d246d2bacbf3b
MBNL1-Associated Mitochondrial Dysfunction and Apoptosis in C2C12 Myotubes and Mouse Skeletal Muscle
Autor:
Shingo Yokoyama, Yoshitaka Ohno, Tatsuro Egawa, Kazuya Ohashi, Rika Ito, Huascar Pedro Ortuste Quiroga, Tomohiro Yamashita, Katsumasa Goto
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 17, p 6376 (2020)
We explored the interrelationship between a tissue-specific alternative splicing factor muscleblind-like 1 (MBNL1) and peroxisome proliferator-activated receptor-γ coactivator 1-α (PGC-1α), B-cell lymphoma 2 (Bcl-2) or Bcl-2-associated X protein (
Externí odkaz:
https://doaj.org/article/ac37fc5584164f84a013f4827b50ea74
Autor:
Tomoya Hayashi, Masatoshi Momota, Etsushi Kuroda, Takato Kusakabe, Shingo Kobari, Kotaro Makisaka, Yoshitaka Ohno, Yusuke Suzuki, Fumika Nakagawa, Michelle S. J. Lee, Cevayir Coban, Risako Onodera, Taishi Higashi, Keiichi Motoyama, Ken J. Ishii, Hidetoshi Arima
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Recently, it was reported that 2-hydroxypropyl-β-cyclodextrin (HP-β-CyD), a common pharmaceutical additive, can act as a vaccine adjuvant to enhance protective type-2 immunogenicity to co-administered seasonal influenza split vaccine by inducing ho
Externí odkaz:
https://doaj.org/article/ad7b4fe64f98488ebd2bc9094ccbfdcc
Autor:
Rika Ito, Masaki Higa, Ayumi Goto, Megumi Aoshima, Akihiro Ikuta, Kazuya Ohashi, Shingo Yokoyama, Yoshitaka Ohno, Tatsuro Egawa, Hirofumi Miyata, Katsumasa Goto
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0205645 (2018)
This study investigated the effects of AdipoRon, which is an agonist for adiponectin receptor 1 (AdipoR1) and AdipoR2, on the protein content, myotube diameter, and number of nuclei per myotube of C2C12 cells and skeletal muscle mass in C57BL/6J mice
Externí odkaz:
https://doaj.org/article/5b49abfca3f64a95847ba4a4cc97994c
Autor:
Tatsuro Egawa, Yoshitaka Ohno, Shingo Yokoyama, Takumi Yokokawa, Satoshi Tsuda, Katsumasa Goto, Tatsuya Hayashi
Publikováno v:
Foods, Vol 8, Iss 10, p 439 (2019)
We investigated the protective effect of Brazilian propolis, a natural resinous substance produced by honeybees, against glycation stress in mouse skeletal muscles. Mice were divided into four groups: (1) Normal diet + drinking water, (2) Brazilian p
Externí odkaz:
https://doaj.org/article/7670b83fcc964ed698b3ac04433cdc16
Autor:
Yoshitaka Ohno, Koki Ando, Takafumi Ito, Yohei Suda, Yuki Matsui, Akiko Oyama, Hikari Kaneko, Shingo Yokoyama, Tatsuro Egawa, Katsumasa Goto
Publikováno v:
Nutrients, Vol 11, Iss 4, p 869 (2019)
The effects of lactate on muscle mass and regeneration were investigated using mouse skeletal muscle tissue and cultured C2C12 cells. Male C57BL/6J mice were randomly divided into (1) control, (2) lactate (1 mol/L in distilled water, 8.9 mL/g body we
Externí odkaz:
https://doaj.org/article/74383635144746a68136501148b28c89
Autor:
Katsumasa Goto, Yoshitaka Ohno, Ayumi Goto, Akihiro Ikuta, Miho Suzuki, Tomotaka Ohira, Noriko Tsuchiya, Sono Nishizawa, Tomoyuki Koya, Tatsuro Egawa, Takao Sugiura, Yoshinobu Ohira, Toshitada Yoshioka
Publikováno v:
Journal of Physical Fitness and Sports Medicine, Vol 1, Iss 2, Pp 197-204 (2012)
Hypertrophic stimuli, such as strength training and exercise, induce the up-regulation of heat shock proteins (HSPs), called stress proteins, in skeletal muscles. However, the physiological roles for induction of HSPs in skeletal muscles are still no
Externí odkaz:
https://doaj.org/article/a8cba5a2675c410eba7e58fcdc330ee5
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 10, p 2954 (2018)
5′AMP-activated protein kinase (AMPK) plays an important role in the regulation of skeletal muscle mass and fiber-type distribution. However, it is unclear whether AMPK is involved in muscle mass change or transition of myosin heavy chain (MyHC) is
Externí odkaz:
https://doaj.org/article/bc7d75ca5c4e493e956257605bb29605
Autor:
Tomoyuki Koya, Sono Nishizawa, Yoshitaka Ohno, Ayumi Goto, Akihiro Ikuta, Miho Suzuki, Tomotaka Ohira, Tatsuro Egawa, Akira Nakai, Takao Sugiura, Yoshinobu Ohira, Toshitada Yoshioka, Moroe Beppu, Katsumasa Goto
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77788 (2013)
Hypertrophic stimuli, such as mechanical stress and overloading, induce stress response, which is mediated by heat shock transcription factor 1 (HSF1), and up-regulate heat shock proteins (HSPs) in mammalian skeletal muscles. Therefore, HSF1-associat
Externí odkaz:
https://doaj.org/article/90b32974e9c94f95ac18ac62a1c1899d
Autor:
Ayumi Goto, Yoshitaka Ohno, Akihiro Ikuta, Miho Suzuki, Tomotaka Ohira, Tatsuro Egawa, Takao Sugiura, Toshitada Yoshioka, Yoshinobu Ohira, Katsumasa Goto
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e81929 (2013)
The purpose of this study was to investigate the expression level of adiponectin and its related molecules in hypertrophied and atrophied skeletal muscle in mice. The expression was also evaluated in C2C12 myoblasts and myotubes. Both mRNA and protei
Externí odkaz:
https://doaj.org/article/7fc7930424ee40fc9630bb7361ca4874