Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Yoshitaka Maki"'
Publikováno v:
Gastroenterology. 81:719-725
Indomethacin produces gastric corpus erosions in the fasted rat and small intestinal ulcers in the conventionally fed rat. We found that in rats fed chow pellets for 1 h after a 24-h fast, indomethacin given within 2 h after refeeding produced lesion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::145e85f6cdcb584dfb3f5dbcb2857abe
https://doi.org/10.1016/0016-5085(81)90497-2
https://doi.org/10.1016/0016-5085(81)90497-2
Autor:
Nobuhiro Inatomi, Nobuhiro Sato, Takenobu Kamada, Nobuto Nakamura, Hiroshi Satoh, Yoshitaka Maki
Publikováno v:
Journal of Gastroenterology and Hepatology. 1:87-96
Changes in gastric mucosal haemoglobin concentration (mucosal blood volume), mucosal haemoglobin oxygenation, mucosal blood flow and gastric arterial blood flow caused by indomethacin, an ulcerogenic agent, and anti-ulcer agents were investigated in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f512137b54dc0539777e058526781504
https://doi.org/10.1111/j.1440-1746.1986.tb00103.x
https://doi.org/10.1111/j.1440-1746.1986.tb00103.x
Autor:
Mikio Honjo, Tsuyoshi Suzuki, Osamu Miyashita, Ryuji Marumoto, Yoshio Yoshioka, Shunsuke Shima, Yoshitaka Maki, Takehiko Naka
Publikováno v:
Chemical and Pharmaceutical Bulletin. 27:990-1003
2-Mono-and 2, 6-di-substituted cAMP (cAMP : adenosine 3', 5'-cyclic phosphate) were derived from the corresponding adenosine analogs via the 5'-phosphates. 2-Substituted cAMP and aristeromycin 3', 6'-cyclic phosphate were led to the 8-bromo derivativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::776a482c3c655a339827251d6340e909
https://doi.org/10.1248/cpb.27.990
https://doi.org/10.1248/cpb.27.990
Publikováno v:
European Journal of Pharmacology. 112:81-87
The protective effect of spizofurone (AG-629) on the rat gastric mucosa was studied in the presence of various stimuli. Spizofurone given orally markedly inhibited gastric lesions induced by ethanol (ED 50 = 6.5 mg/kg). Spizofurone inhibited ethanol-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f36d75823d0a0fbe676e74318dfab025
https://doi.org/10.1016/0014-2999(85)90241-9
https://doi.org/10.1016/0014-2999(85)90241-9
Publikováno v:
European Journal of Pharmacology. 141:299-304
The effect on guinea pig airways of the inhalation of leukotrienes, histamine or antigen was investigated by measuring changes in lung volume and analyzing the airway area on bronchograms with the Zeiss interactive image analysis system (IBAS). LTC 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21e6bec054e99c88541c06caef9ab9c4
https://doi.org/10.1016/0014-2999(87)90275-5
https://doi.org/10.1016/0014-2999(87)90275-5
Publikováno v:
Japanese Journal of Pharmacology. 31:593-599
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16f24d1da81baa1d0cdb2335f5493698
https://doi.org/10.1016/s0021-5198(19)52823-2
https://doi.org/10.1016/s0021-5198(19)52823-2
Autor:
Taketoshi Saijo, Hisashi Kuriki, Yasushi Sanno, Kiyoshi Ukawa, Toshihiro Ishiguro, Akira Nohara, Yoshitaka Maki
Publikováno v:
Journal of Medicinal Chemistry. 22:290-295
The metabolites of 6-ethyl-3-(1H-tetrazol-5-yl)chromone (AA-344) (1), an orally effective antiallergic agent, and their analogues were synthesized to confirm the proposed structures and to determine their activity in the rat passive cutaneous anaphyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f1529c61fcbd544e0f2fb60e7aefa56
https://doi.org/10.1021/jm00189a014
https://doi.org/10.1021/jm00189a014
Publikováno v:
European Journal of Pharmacology. 124:149-155
The effect of spizofurone, a new anti-ulcer agent, on alkaline secretion was studied in an isolated sheet of bullfrog proximal duodenal mucosa mounted in an Ussing chamber. Spizofurone (10−4-10−3 M) as well as prostaglandin E2 (PGE2, 10−8-10−
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74bb3d4ca0afb1ada2b841654fa50454
https://doi.org/10.1016/0014-2999(86)90135-4
https://doi.org/10.1016/0014-2999(86)90135-4
Publikováno v:
Ensho. 7:563-567
Bromelain-induced edema in rats was studied and compared to carrageenin-induced edema. The edema reached a maximum 30 min after Bromelain was injected subcutaneously into the rat paw, then decreased slowly, and had almost disappeared 24 hr later. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d5be1ca73c0556047f6dd56f7b1809b
https://doi.org/10.2492/jsir1981.7.563
https://doi.org/10.2492/jsir1981.7.563
Publikováno v:
Chemical and Pharmaceutical Bulletin. 31:560-569
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b09fe216979fda5def984eb18ecd2b5c
https://doi.org/10.1248/cpb.31.560
https://doi.org/10.1248/cpb.31.560