Výsledky vyhledávání - "Yoshitaka MATSUSHIMA"

Akademický článek

Mass spectrometric profiling of DNA adducts in the human stomach associated with damage from environmental factors

Autor: Ippei Ohnishi, Yuji Iwashita, Yuto Matsushita, Shunsuke Ohtsuka, Takashi Yamashita, Keisuke Inaba, Atsuko Fukazawa, Hideto Ochiai, Keigo Matsumoto, Nobuhito Kurono, Yoshitaka Matsushima, Hiroki Mori, Shioto Suzuki, Shohachi Suzuki, Fumihiko Tanioka, Haruhiko Sugimura

Publikováno v: Genes and Environment, Vol 43, Iss 1, Pp 1-13 (2021)

Abstract Background A comprehensive understanding of DNA adducts, one of the most plausible origins of cancer mutations, is still elusive, especially in human tissues in clinical settings. Recent technological developments have facilitated the identi

Externí odkaz: https://doaj.org/article/ddd4e21bbe964e13bed448c0e7778f0d

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Akademický článek

Concise and scalable synthesis of (±)-phosphonothrixin

Autor: Yoshitaka Matsushima, Koki Nakamura

Publikováno v: Results in Chemistry, Vol 3, Iss , Pp 100251- (2021)

A concise and scalable method for the synthesis of (±)-phosphonothrixin (1), an herbicidal antibiotic containing a C–P bond, was developed. We developed a simpler and more responsible method for the synthetic precursor, epoxy alcohol 2. The synthe

Externí odkaz: https://doaj.org/article/ec4723d48c37437ab9e9599e3bf9f9cc

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Concise synthesis of amino acid component of amicoumacins via dihydrooxazine formation through intramolecular conjugate addition

Autor: Yoshitaka, Matsushima, Yukako, Ogawa, Katsuya, Nishi, Kyosuke, Nakata

Publikováno v: Bioscience, Biotechnology, and Biochemistry. 87:131-137

Amicoumacins are a family of antibiotics with a variety of important bioactivities. A concise and efficient method was developed for synthesizing the amino acid component of amicoumacins via the corresponding dihydrooxazine intermediate. The dihydroo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d15601adeb6495668942f2331a89c766
https://doi.org/10.1093/bbb/zbac182

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Enantioselective total syntheses of (S)-phosphonothrixin and unexpected cyclic derivative (S)-cyclic phosphonothrixin via enzymatic resolution

Autor: Koki, Nakamura, Yoshitaka, Matsushima

Publikováno v: Bioscience, Biotechnology, and Biochemistry. 87:138-147

(S)-Phosphonothrixin is a phosphonate natural product produced by Saccharothrix sp. ST-888 that exhibits herbicidal activity. The previously reported asymmetric synthesis of (S)-phosphonothrixin is laborious and difficult to reproduce. In this study,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9909c357fa98cfbf5e7c9874c0d4df75
https://doi.org/10.1093/bbb/zbac188

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Isolation of phenolic acids and tannin acids from Mangifera indica L. kernels as inhibitors of lipid accumulation in 3T3-L1 cells

Autor: Takahiro Fujimaki, Chikako Sato, Rei Yamamoto, Sayo Watanabe, Hikaru Fujita, Hidehiko Kikuno, Masayuki Sue, Yoshitaka Matsushima

Publikováno v: Bioscience, Biotechnology, and Biochemistry. 86:665-671

Mango (Mangifera indica L.) kernels are usually discarded as waste, but they contain many pharmacological properties and bioactivities. In this study, we isolated antiobesity agents from mango kernels that inhibit intracellular lipid formation in 3T3

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b36891f8dc18cbdbacf1468d2853df6c
https://doi.org/10.1093/bbb/zbac030

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Mass spectrometric profiling of DNA adducts in the human stomach associated with damage from environmental factors

Autor: Fumihiko Tanioka, Shioto Suzuki, Yuji Iwashita, Hiroki Mori, Haruhiko Sugimura, Keigo Matsumoto, Hideto Ochiai, Yoshitaka Matsushima, Ippei Ohnishi, Keisuke Inaba, Atsuko Fukazawa, Shohachi Suzuki, Yuto Matsushita, Takashi Yamashita, Nobuhito Kurono, Shunsuke Ohtsuka

Publikováno v: Genes and Environment, Vol 43, Iss 1, Pp 1-13 (2021)
Genes and Environment

Background A comprehensive understanding of DNA adducts, one of the most plausible origins of cancer mutations, is still elusive, especially in human tissues in clinical settings. Recent technological developments have facilitated the identification

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5338cf05dc955f6d158918e950922319
https://doaj.org/article/ddd4e21bbe964e13bed448c0e7778f0d

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