Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Yoshitaka Higa"'
Publikováno v:
Aerospace Science and Technology. 130:107879
Autor:
Kyoko Nabae, Yoshitaka Higa, Yosuke Toda, Takumi Hara, Noriho Tanaka, Mayumi Kawabe, Sachiko Kitamoto, Kimio Kariya, Michihito Takahashi
Publikováno v:
The Journal of Toxicological Sciences. 32:143-159
Kojic acid (KA) has been widely used as a quasi-drug ingredient. Possible promotion activity of KA was suggested on livers of mouse and rat by findings obtained in genotoxicity and carcinogenicity studies performed thus far. Therefore, in order to ex
Publikováno v:
The Journal of Toxicological Sciences. 25:167-175
To elucidate the effects of kojic acid on thyroid function, the compound was given orally to male rats for 4 weeks at 0, 4, 15, 62.5, 250 and 1,000 mg/kg. In 1,000 mg/kg treatment of kojic acid, the rats showed a slight decrease in motility, inhibiti
Autor:
Sumiko Ohashi-Kunihiro, Eiji Ohshima, Hideaki Koike, Tomohiro Ando, Junichiro Marui, Yoshitaka Higa, Shinichi Ohashi, Masayuki Machida, Noriko Yamane, Yasunobu Terabayashi, Motoaki Sano, Marie Nishimura, Kuniharu Tachibana
Publikováno v:
Journal of bioscience and bioengineering. 112(1)
A gene encoding the Zn(II)(2)Cys(6) transcriptional factor is clustered with two genes involved in biosynthesis of a secondary metabolite, kojic acid (KA), in Aspergillus oryzae. We determined that the gene was essential for KA production and the tra
Autor:
Ken Oda, Yasunobu Terabayashi, Motoaki Sano, Eiji Ohshima, Koichi Tamano, Junichiro Marui, Masayuki Machida, Mitsuko Dohmoto, Hideaki Koike, Kuniharu Tachibana, Jun-Ichi Sagara, Noriko Yamane, Yoshitaka Higa, Shinichi Ohashi
Publikováno v:
Fungal genetics and biology : FGB. 47(12)
Kojic acid is produced in large amounts by Aspergillus oryzae as a secondary metabolite and is widely used in the cosmetic industry. Glucose can be converted to kojic acid, perhaps by only a few steps, but no genes for the conversion have thus far be
Publikováno v:
The Journal of toxicological sciences. 27(5)
The effects of kojic acid (KA) on thyroidal function were studied by single-dose administration in rats and in cultured rat thyroid cells (FRTL-5 cells). In rats receiving a single dose of 1,000 mg/kg KA orally, the 125I uptake from blood into the th