Zobrazeno 1 - 10
of 314
pro vyhledávání: '"Yoshitaka HIROOKA"'
Autor:
Kanyarat Boonpeng, Tatsuki Shibuta, Yoshitaka Hirooka, Kasem Kulkeaw, Duangdao Palasuwan, Tsukuru Umemura
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Glucose-6-phosphate dehydrogenase (G6PD) deficiency is one of the most common enzymopathies worldwide. Patients with G6PD deficiency are usually asymptomatic throughout their life but can develop acute hemolysis after exposure to free radica
Externí odkaz:
https://doaj.org/article/2fd747ff5e4e45da902b22f9e3a0c878
Autor:
Risa Shibata, Keisuke Shinohara, Shota Ikeda, Takeshi Iyonaga, Taku Matsuura, Soichiro Kashihara, Koji Ito, Takuya Kishi, Yoshitaka Hirooka, Hiroyuki Tsutsui
Publikováno v:
Clinical and Experimental Hypertension, Vol 44, Iss 3, Pp 249-257 (2022)
Introduction Increased sympathetic output contributes to cardiac hypertrophy. Sympathoexcitation is induced by activating the cardiac sympathetic afferent nerves through transient receptor potential vanilloid 1 (TRPV1) in cardiac afferent endings. Br
Externí odkaz:
https://doaj.org/article/1103016b01374d6186998884a8a948de
Publikováno v:
Clinical and Experimental Hypertension, Vol 41, Iss 3, Pp 211-219 (2019)
Background: Augmented sympathetic nerve activity (SNA) and renin-angiotensin-aldosterone system (RAAS) activity are involved in the pathogenesis of hypertension (HT) accompanied by chronic kidney disease (CKD). Oxidative stress in the hypothalamus in
Externí odkaz:
https://doaj.org/article/7fe1932221d04ad4b6b193e4c7fd11e4
Publikováno v:
International Journal of Hypertension, Vol 2015 (2015)
Abnormal blood pressure (BP) elevation in early morning is known to cause cardiovascular events. Previous studies have suggested that one of the reasons in abnormal dairy BP variability is sympathoexcitation. We have demonstrated that brain angiotens
Externí odkaz:
https://doaj.org/article/eb5b2a263ffa4d19acfc8b3b6d0bb047
Autor:
Tomomi Nagayama, Yoshitaka Hirooka, Akiko Chishaki, Masao Takemoto, Yasushi Mukai, Shujiro Inoue, Takuya Kishi, Kenji Sunagawa
Publikováno v:
International Journal of Hypertension, Vol 2014 (2014)
Objective. Many previous clinical studies have suggested that atrial fibrillation (AF) is closely associated with hypertension. However, the benefits of antihypertensive therapy on AF are still inconsistent, and it is necessary to explore the factors
Externí odkaz:
https://doaj.org/article/25dba169ab034b7fa769d0c31863d5f0
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69053 (2013)
BACKGROUND: Left ventricular (LV) remodeling and activation of sympathetic nervous system (SNS) are cardinal features of heart failure. We previously demonstrated that enhanced central sympathetic outflow is associated with brain toll-like receptor 4
Externí odkaz:
https://doaj.org/article/299c3d1a13784db3a24393ef3b19f00a
Autor:
Takuya Kishi, Yoshitaka Hirooka
Publikováno v:
International Journal of Hypertension, Vol 2013 (2013)
Renin-angiotensin system (RAS) is activated in metabolic syndrome (MetS), and RAS inhibitors are preferred for the treatments of hypertension with MetS. Although RAS activation is important for the therapeutic target, underlying sympathetic nervous s
Externí odkaz:
https://doaj.org/article/52dd421fbc914e23af6abf612d1e1f1e
Autor:
Takuya Kishi, Yoshitaka Hirooka
Publikováno v:
Cardiology Research and Practice, Vol 2012 (2012)
It has been recognized that the sympathetic nervous system is abnormally activated in chronic heart failure, and leads to further worsening chronic heart failure. In the treatment of chronic heart failure many clinical studies have already suggested
Externí odkaz:
https://doaj.org/article/55f0d685ec6c4755bbb9e98e0063e494
Autor:
Fumiaki Nakashima, Tsukasa Watanabe, Yoshiyuki Tomiyoshi, Kazuhisa Ejima, Takateru Ootsuka, Junichi Nojiri, Kazuma Fujimoto, Yoshitaka Hirooka
Publikováno v:
International Heart Journal. 64:109-113
Autor:
Futoshi Kawaura, Takuya Kishi, Tadashi Yamamoto, Shiki Nakayama, Taku Goto, Reimi Tsurusawa, Toshio Katagiri, Kohei Yamanouchi, Ayako Matsuo, Naomi Kobayashi-Watanabe, Tomohiro Imamura, Yoshitaka Hirooka, Kuniyasu Takagi, Tsukuru Umemura, Kazuma Fujimoto, Shinichiro Hayashi, Ayako Takamori
Publikováno v:
Drug Discoveries & Therapeutics. 17:60-65