Výsledky vyhledávání - "Yoshitaka HIROOKA"

Akademický článek

Serum microRNAs as new biomarkers for detecting subclinical hemolysis in the nonacute phase of G6PD deficiency

Autor: Kanyarat Boonpeng, Tatsuki Shibuta, Yoshitaka Hirooka, Kasem Kulkeaw, Duangdao Palasuwan, Tsukuru Umemura

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)

Abstract Glucose-6-phosphate dehydrogenase (G6PD) deficiency is one of the most common enzymopathies worldwide. Patients with G6PD deficiency are usually asymptomatic throughout their life but can develop acute hemolysis after exposure to free radica

Externí odkaz: https://doaj.org/article/2fd747ff5e4e45da902b22f9e3a0c878

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Akademický článek

Transient receptor potential vanilloid 1-expressing cardiac afferent nerves may contribute to cardiac hypertrophy in accompany with an increased expression of brain-derived neurotrophic factor within nucleus tractus solitarius in a pressure overload model

Autor: Risa Shibata, Keisuke Shinohara, Shota Ikeda, Takeshi Iyonaga, Taku Matsuura, Soichiro Kashihara, Koji Ito, Takuya Kishi, Yoshitaka Hirooka, Hiroyuki Tsutsui

Publikováno v: Clinical and Experimental Hypertension, Vol 44, Iss 3, Pp 249-257 (2022)

Introduction Increased sympathetic output contributes to cardiac hypertrophy. Sympathoexcitation is induced by activating the cardiac sympathetic afferent nerves through transient receptor potential vanilloid 1 (TRPV1) in cardiac afferent endings. Br

Externí odkaz: https://doaj.org/article/1103016b01374d6186998884a8a948de

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Akademický článek

Olmesartan combined with renal denervation reduces blood pressure in association with sympatho-inhibitory and aldosterone-reducing effects in hypertensive mice with chronic kidney disease

Autor: Masaaki Nishihara, Ko Takesue, Yoshitaka Hirooka

Publikováno v: Clinical and Experimental Hypertension, Vol 41, Iss 3, Pp 211-219 (2019)

Background: Augmented sympathetic nerve activity (SNA) and renin-angiotensin-aldosterone system (RAAS) activity are involved in the pathogenesis of hypertension (HT) accompanied by chronic kidney disease (CKD). Oxidative stress in the hypothalamus in

Externí odkaz: https://doaj.org/article/7fe1932221d04ad4b6b193e4c7fd11e4

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Serum High-Sensitivity C-Reactive Protein Levels and the Development of Atrial Fibrillation in a General Japanese Population ― The Hisayama Study ―

Autor: Takanari Kitazono, Toshiharu Ninomiya, Satoko Sakata, Takuya Nagata, Tomoko Yoshikawa, Yoichiro Hirakawa, Yoshitaka Hirooka, Hiroyuki Tsutsui, Jun Hata

Publikováno v: Circulation Journal. 85:1365-1372

BACKGROUND Atrial fibrillation (AF) is a common arrhythmia in the elderly, and causes complications such as cardioembolic stroke. Serum high-sensitivity C-reactive protein (hs-CRP), a marker of systemic inflammation, has been reported to be a risk fa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a207d5faae169ccf36fe8f9322123b7
https://doi.org/10.1253/circj.cj-20-0751

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Diagnosis of type 2 Diabetes Mellitus (T2DM) using Paired microRNAs

Autor: Yukichi Takada, Yasuhiro Ono, Tatsuki Shibuta, Ayaka Ishibashi, Ayako Takamori, Kazuma Fujimoto, Yoshitaka Hirooka, Tsukuru Umemura

Type 2 Diabetes mellitus (T2DM) is one of the most common diseases in the world and its prevalence ratio is still increasing. Patients with T2DM have diverse pathophysiological changes like as macrovascular, microvascular diseases, cancers as well as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::10686130a0a8bb0857c06612a2c6a90f
https://doi.org/10.1101/2022.09.29.510072

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A Retrospective Analysis of Risk Factors for Mortality during Hemodialysis at a General Hospital that Treats Comprehensive Diseases

Autor: Akira Kitajima, Takuya Kishi, Kohei Yamanouchi, Yoshitaka Hirooka, Shuji Toda, Ayako Takamori, Kazuma Fujimoto, Chie Kishi, Yoshiyuki Tomiyoshi

Publikováno v: Internal medicine (Tokyo, Japan).

Objective We analyzed adverse events retrospectively during a three-year follow-up of patients undergoing hemodialysis at the dialysis center of our general hospital that can treat comprehensive diseases and conducted an exploratory study focusing on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5a22b51ac05346124a48e1cd5e8b73d
https://pubmed.ncbi.nlm.nih.gov/36104191

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